D.

Pharm Ist year

PHARMACEUTICS
( ER20 – 11P )

PRACTICAL LAB MANUAL

Prepared By :

Mr. Pankaj Gill

( Assistant Professor)
M.Pharm (Pharmaceutics), P.hD*
School of Pharmaceutical Science
Shri Venkateshwara University
 Contents
Syllabus… ....................................................................................................................................................
Preparation of simple syrup… .......................................................................................................................
Preparation of Piperazine citrate elixir ...........................................................................................................
Preparation of aqueous iodine solution .........................................................................................................
Preparation of Castor oil emulsion ................................................................................................................
Preparation of Cod Liver Oil emulsion .........................................................................................................
Preparation of Calamine lotion ......................................................................................................................
Preparation of Magnesium Hydroxide mixture ..............................................................................................
Preparation of Simple ointment .....................................................................................................................
Preparation of Sulphur ointment ....................................................................................................................
Preparation of Cetrimide cream .....................................................................................................................
Preparation of Sodium alginate gel… ............................................................................................................
Preparation of Turpentine Liniment..............................................................................................................
Preparation of White Liniment ......................................................................................................................
Preparation of Effervescent granules .............................................................................................................
Preparation of Dusting powder ......................................................................................................................
Preparation of Sodium chloride injection.......................................................................................................
Preparation of Calcium gluconate injection ..................................................................................................
Preparation of Tetracycline Capsule ..............................................................................................................
Preparation of Paracetamol Tablet.................................................................................................................
Preparation of Shampoo ...............................................................................................................................
Preparation of Cold cream .............................................................................................................................
Preparation of Lipsticks ................................................................................................................................
Preparation of Vanishing cream ...................................................................................................................
Preparation of Face powder...........................................................................................................................
Preparation of Toothpaste .............................................................................................................................
 SYLLABUS
1. Handling and referring the official references: Pharmacopoeias, Formularies, etc. for retrieving
formulas, procedures, etc.

2. Formulation of the following dosage forms as per monograph standards and dispensing with
appropriate packaging and labelling.
 Liquid Oral: Simple syrup, Piperazine citrate elixir, Aqueous Iodine solution.
 Emulsion: Castor oil emulsion, Cod liver oil emulsion.
 Suspension: Calamine lotion, Magnesium hydroxide mixture.
 Ointment: Simple ointment base, Sulphur ointment.
 Cream: Cetrimide cream.
 Gel: Sodium alginate gel.
 Liniment: Turpentine liniment, White liniment BPC.
 Dry powder: Effervescent powder granules, dusting powder.
 Sterile Injection: Normal Saline, Calcium Gluconate Injection.
 Hard Gelatin Capsule: Tetracycline capsules.
 Tablet: Paracetamol tablets.

3. Formulation of at least five commonly used cosmetic preparations – e. g. cold cream, shampoo,
lotion, tooth paste etc.

4. Demonstration on various stages of tablet manufacturing processes.

5. Appropriate methods of usage and storage of all dosage forms including special dosage such as
different types of inhalers, spacers, insulin pens.

6. Demonstration of quality control tests and evaluation of common dosage forms viz. tablets,
capsules, emulsion, and sterile injections as per the monographs.
 Exp. No. 1 Date:
Aim: To prepare and submit 30 ml of Simple Syrup IP.

Reference:
1. Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 155 – 156.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, stirrer etc.
Chemical Required:
Sucrose and purified water.
Principle:
Syrups are sweetened, viscous, concentrated solutions of sucrose or other sugars in water or anyother
suitable aqueous vehicles. These are further classified into 2 classes.
1. Simple flavored syrups
2. Medicated syrups
Simple flavor syrups:
Do not contain any medicament or drug. These syrups are used as a vehicle for other Liquid
preparation to mask the disagreeable taste of drug.
Medicated syrups:
These contain some medicinal substance along with their other additives. Sucrose concentration in
simple syrup is a 66.7 %w/w.
Formula:

Sl. No. Ingredients Official formula Requiredquantities

1 Sucrose 667gm
2 Purified water, quantity 1000ml 30ml
sufficient to produce (q. s)

Calculations:

Procedure:
Add water to sucrose in a beaker and heat on water bath until sucrose dissolves add sufficient boiling
water to produce the final volume. Filter hot syrup through cotton wool. cool the syrup and
preservatives may be added for stability. Add more purified water to make up the required volume.
Filter and transfer in a suitable container.
Category:
Sweetening agent, vehicle
Use:
Simple Syrups are used as vehicles for drugs such as antibiotics, Antihistaminic, antitussives and
vitamins.

Storage:
Stored in a well closed container at a temperature not exceeding 250C.
Label:
 SIMPLE SYRUP IP
30ml
Composition:
Sucrose BATCH NO. MFG. DATE:
Purified water
MFG. LIC. NO.: EXPIRY DATE:
Category: Sweetening agent, vehicle

FOR INTERNAL USE ONLY.

Use: Simple Syrups are used as vehicles for drugs such as antibiotics, Antihistaminic, antitussives
and vitamins.
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding 250C
MFG. BY: ABCD Batch: Roll No.:

Report:
 Exp. No. 2 Date:
Aim: To prepare and submit 20ml of Piperazine citrate elixir.
Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 158 - 160
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker etc.
Chemical Required:
Piperazine citrate, chloroform spirit, glycerin, orange oil, syrup, purified water.
Principle:
Piperazine Citrate Elixir is mainly an anthelmintic. This kind of drug works to paralyze parasites that
may invade the host body and cause diseases. It therefore helps to remove the parasites andthus
inhibit the spread of disease in the body. The medicine is used totreat
ascariasis, enterobiasis, also called common pinworms. The drug immobilizes the parasitic worms
first, which are later passed out of the body through stool. This drug can only be obtained with a
proper prescription by your doctor and is not available over the counter. The medicine is available in
the form a tablet or as syrup.

Formula:

Sl. No. Ingredients Official Required

Formula quantities
1 Piperazine citrate 180gm
2 Chloroform spirit 0.5ml
3 Glycerine 100ml
4 Orange oil 0.25ml
5 Syrup 500ml
6 Purified water 1000ml 20ml

Calculation:

Procedure:
Dissolve piperazine citrate in part of water. Then mix with agitation orange oil, glycerin, syrup in
chloroform spirit and pour in watery solution of piperazine citrate. Adjust the volume with
sufficient purified water. Filter and transfer in a suitable container.

Storage:
Stored in a well closed container at a temperature not exceeding 250C.

Use:
It is used as anthelmintic which is used in the treatment of worm infections.
Label:

PIPERAZINE CITRATE ELIXIR

20ml
Composition:
Piperazine citrate
Chloroform spirit BATCH NO. MFG. DATE:

Glycerin
MFG. LIC. NO.: EXPIRY DATE:
Orange oil
Syrup
Purified water
Category: Anthelmintic
FOR INTERNAL USE ONLY.
Use: It is used as an anti-helminthics are used in the treatment of worm infections.

Storage: Stored in a well closed container dark in a cool place and temperature not exceeding
250C

MFG BY: ABCD Batch: Roll No.:

Report
 Exp. No. 3 Date:
Aim: To prepare and submit 30ml of aqueous iodine solution.
Reference:
Gupta A.K., Jain V.K., Pharmaceutics-I Practical Note Book, CBS Publishers & Distributors
Pvt.Ltd.2020; 15
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Iodine, potassium iodide and purified water
Principle:
In pharmaceutical practice solution are defined as liquid preparation containing one or morechemical
substances usually dissolved in water. Aqueous iodine solution is also known as Lugol’s Solution
and contain 5%w/v of iodine and 10% w/v of potassium iodide.

Formula:

Sl. No. Ingredients Official formula Working formula Required quantities

1 Iodine 50gm

2 Potassium iodide 100gm

3 Purified water 1000ml 30ml

Calculation:

Procedure:
Dissolve potassium iodide and iodine in a purified water. Shake well till it dissolve. Then add
sufficient purified water to make up the required volume. Filter and transfer in a suitable container.

Use: Antiseptic

Storage: Well closed container made up of iodine resistant material.

Dose: 0.3 to 2ml.

Label:

AQUEOUS IODINE SOLUTION

30ml
Composition:
Iodine
BATCH NO.: MFG. DATE:
Potassium iodide
Purified water
MFG. LIC NO.: EXPIRY DATE:
Category: Antiseptic

FOR EXTERNAL USE ONLY

Use: It is used as an antiseptic
Storage: Stored in a well closed container at a temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-4 Date:
Aim: To prepare and submit 30ml of Castor oil emulsion.
Reference:
1. Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017;217
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required: Castor oil and Cinnamon water q. s.
Principle:
An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or
unblendable) owing to liquid-liquid phase separation. Depending upon the nature of the dispersed
phase, the emulsions are classified as (i) Water-in-oil emulsion (W/O) (ii) oil in water emulsion (O/W)
Liquid paraffin is primarily used as a pediatric laxative in medicine and is a populartreatment
for constipation and encopresis. Castor oil emulsion is used as a laxative, to empty the GI tract, while
the patients is prepared for thecolon X –ray, proctoscopy and endoscopic examination.

Formula:

Sl. Ingredients Official Working formula Required

No. formula quantities

1 Castor oil 20ml

2 Cinnamon water q. 50ml 25ml

s.

Calculation:
Procedure:
 Weigh calculated quantity of acacia is take in a mortar.
 Measured quantity of cinnamon water at once (calculated for primary emulsion formula) is added
into the mortar.
 The content, in the mortar is triturated to form mucilage.
 Measured quantity of castor oil is added in small quantities, with constant, rapid and light trituration
to produce a thick cream. Trituration is continued for three minutes to obtain a white stable emulsion.
It is indicated by click sound.
 Some more quantity of cinnamon water is added gradually with continuous trituration.
 The contents are transferred into a measuring cylinder.
 The pestle and mortar are rinsed with cinnamon water and rinsing are transferred into the measuring
cylinder.
 The quantity is adjusted to the required volume using cinnamon water and the contents are stirred
well.
 The castor oil emulsion is then transferred into a wide mouthed light resistant container.
 The bottle is capped, labelled, polished and submitted.
 Use: Castor oil emulsion is used as a laxative, to empty the GI tract, while the patients is preparedfor
the colon X –ray, protoscopy and endoscopic examination.

Storage: It should be store in a tightly –closed container in a cool place.

Category: Laxative.
Dose: 4 -6 ml
Direction: Take on an empty stomach followed with one full glass of water.

Label:

CASTOR OIL EMULSION

25ml
Composition:
Castor oil BATCH NO. MFG. DATE:
Cinnamon water q.s
MFG. LIC. NO.: EXPIRY DATE:

Category: Laxative

FOR INTERNAL USE ONLY.

Use: Castor oil emulsion is used as a laxative, to empty the GI tract, while the patients are prepared
for the colon X –ray, protoscopy and endoscopic examination.

Storage: It should be store in a tightly –closed container in a cool place.

MFG BY: ABCD Batch: Roll No.:

Report:
Exp. No.-5 Date:
Aim: To prepare and submit 30ml of Cod Liver Oil emulsion.
Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017;217
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required: Cod liver oil, Egg yolk, Purified water q.s
Principle:
An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or
unblendable) owing to liquid-liquid phase separation. Depending upon the nature of the dispersed
phase, the emulsions are classified as (i) Water-in-oil emulsion (W/O) (ii) oil in water emulsion (O/W).
Cod liver oil is a rich sources of vitamin D and therefore used as an anti-rachitic agent.

Formula:

Sl. Ingredients Official Working formula Required

No. formula quantities

1 Cod liver oil 30ml

2 Egg yolk 4ml
3 water q.s 60ml 30ml

Calculation:

Procedure:
 Egg yolk is separated from the broken egg and placed in a measure. Equal volume of wateris added
and mixed thoroughly.
 The calculated volume of the above egg yolk is placed in a mortar.
 The calculated volume of cod liver oil is added to the mortar and mixed with constantstirring.
 Purified water (1/3rd the total quantity0 is gradually added with constant trituration.
 The mixture is strained through a muslin cloth.
 Mortar and pestle are rinsed with little volume of water and transferred through the muslincloth.
 The volume is adjusted to the required level with water in a measuring cylinder.
 The contents are mixed well and transferred into a narrow-mouthed container
 The container is capped, polished, labelled and dispensed.

Use: It is used as an Anti-rachitic agent (in deficiency of vitamin D).

Storage: It should be store in a tightly well closed container in a cool place.
Category: Anti-rachitic (in deficiency of vitamin D)
Dose: Not more than 10ml daily.
 Label:

COD LIVER OIL EMULSION

30ML
Composition:
Cod liver oil BATCH NO. MFG. DATE:
Egg yolk
MFG. LIC. NO.: EXPIRY DATE:
Purified water q. s
Category: Anti-rachitic (in deficiency of
vitamin D)
FOR INTERNAL USE ONLY
Use: It is used as an Anti-rachitic agent (in deficiency of vitamin D)

Storage: It should be store in a tightly well closed container in a cool place.

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-6 Date:
Aim: To prepare and submit 30ml of Calamine lotion.
Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 165 -166
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Calamine, Zinc oxide, Bentonite, Glycerin, sodium citrate, Liquefied phenol, rose water,
Purified water.
Principle:
It is a suspension containing in-diffusible Solids for external use. Here we use bentonite as a
suspending agent, dispersion of bentonite is observed if it is mixed intimately with insoluble
medicament i.e. calamine. Zinc oxide used here acts as astringent & protective agent. Sodium citrate
causes partial deflocculation of calamine and transfers bentonite from gel to solid form in its absence.
Hence it is thicker & difficult to pour from bottle.

Formula:

Sl. No. Ingredients Official Working formula Required quantities

formula
1 Calamine 150gm
2 Zinc oxide 50gm
3 Bentonite 15gm
4 Glycerine 5ml
5 Sodium citrate 5ml
6 Liquefied phenol 50ml
7 Rose water 1000ml 30ml

Calculation:

Procedure:
 Mix the weighed amounts of Calamine, ZnO, Bentonite in a mortar & pestle.
 Triturate with a solution of sodium citrate in 5 ml of water.
 Add required amounts of liquefied phenol & Glycerine.
 Mix well, to this add more of vehicle to produce required volume, mix thoroughly so as to get
uniform preparation. Filter and transfer in a suitable container. 
Directions:
Shake well before use. To be applied 2-3 times a day.
Uses:
 This is used as astringent.
 Used as smoothening agent and gives relief from itching and pain during skin diseases and
infections.
 It is also used in ring worm infections.

Storage: Stored in a well closed container dark in a cool place at a temperature not exceeding250C.
Label:
CALAMINE LOTION
30ml
Composition:
Calamine
Zinc oxide BATCH NO. MFG. DATE:
Bentonite
Glycerine
Sodium citrate MFG. LIC. NO.: EXPIRY DATE:
Liquefied phenol
Rose water
Category: Astringent
FOR EXTERNAL USE ONLY
Use: This is used as astringent
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-7 Date:
Aim: To prepare and submit 20ml of Magnesium Hydroxide mixture.

Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 150-151.
 Subrahmanyam C.V.S., Thimmasetty J.J, Prabhushankar G.L., Laboratory manualof Pharmaceutics.
Vallabh Publication, Delhi, 2019; 47-48.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Magnesium sulphate, sodium hydroxide, light magnesium oxide and purified water.
Principle:
It is aqueous of colloidal dispersion of magnesium hydroxide. It is prepared by precipitation method
and hydration method or both. It is not excessively thick or thin but holds design viscosity, it has two
actions in low dose (1 -4ml) it acts as an antacid, while in higher dose (8–10ml) it acts as a laxative.
Reaction:
MgO +H2O ------- Mg (OH)2 Mg SO4+ 2NaOH-------------------------- Mg (OH)2 + Na2SO4

Formula:

Sl. Ingredients Official formula Working Required quantities

No. formula
1 Magnesium sulfate 47.5gm
2 Sodium hydroxide 50.5gm
3 Light magnesium 15gm
oxide
4 Purified water 1000ml 20ml

Calculation:

Procedure:
 Dissolve sodium hydroxide in sufficient purified water contained in a beaker.
 Triturate Magnesium oxide in a mortar with the solution of hydroxide to from a
smoothcream.
 Dissolve magnesium sulphate in sufficient water in a separate beaker.
 Add cream to the solution of magnesium sulphate with constant stirring. This mixture is
setaside for 48 hrs.
 After 48 hrs pour off the supernatant liquid.
 Add hot purified water to the precipitate of magnesium hydroxide to wash the sulphate
 ionsfrom precipitate.
 Transfer the washed precipitate to the suitable container and label it.
Dose: 1 to 4ml as antacid, 8 to 10ml as laxative.
Storage: Stored in an air tight container in a cool place.
Direction: Shake well before use
Label:
MAGNESIUM HYDROXIDE MIXTURE
20ml
Composition:
Magnesium sulfate BATCH NO. MFG. DATE:
Sodium hydroxide
Light magnesium oxide MFG. LIC. NO.: EXPIRY DATE:
Purified water
Category: Laxative.
FOR INTERNAL USE ONLY
Use: Laxative & Antacid
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-8 Date:
Aim: To prepare and submit 100gm of Simple ointment.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017;238
 Pharmacopoeia of India.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, ointments slab etc.
Chemical Required:
Wool fat, hard paraffin, white soft paraffin, cetostearyl alcohol.
Principle:
Ointments are semisolid preparation meant for external application to the skin or mucous membrane.
They usually contain medicament or medicaments which are dissolved or dispensed or suspended or
emulsified as an antiseptic, antifungal agent.
Formula:
Sl. No. Ingredients Official Working Required
formula formula quantities
1 Wool fat 5gm
2 Hard paraffin 5gm
3 Cetostearyl 5gm
alcohol
4 White soft 85gm
paraffin

Calculations:

Procedure:
 Melt hard paraffin and Cetostearyl alcohol on water bath.
 To this incorporate wool fat and white soft paraffin.
 Stir until all ingredients are melted.
 Examine the contents for any foreign particles. Decant or strain if required.
 Stir the mixture thoroughly until cold.
 Pack it in an ointment jar, label, and dispense.
Direction: Apply as directed.
Use: This are used to treat seborrheic dermatitis and scabies.
Storage: Keep in well closed container and cool place.
Label:

SIMPLE OINTMENT
100gm

Compositions:
Wool fat BATCH NO. MFG. DATE:
Hard paraffin
Cetostearyl alcohol MFG. LIC. NO.: EXPIRY DATE:
White soft paraffin
Category: Acne

FOR EXTERNAL USE ONLY.

Use: This are used to treat acne and also used to treat seborrheic dermatitis and scabies.

Storage: Stored in a well closed container dark and cool place and temperature not exceeding 250C

MFG BY: Batch: Roll No.:

Report:
 Exp. No.-9 Date:
Aim: To prepare and submit 100gm of Sulphur ointment I.P.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017;238
 Pharmacopoeia of India.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, ointments slab etc.
Chemical Required:
Sublimed Sulphur, wool fat, hard paraffin, white soft paraffin, Cetostearyl alcohol.
Principle:
Ointments are semisolid preparation meant for external application to the skin or mucous membrane.
They usually contain medicament or medicaments which are dissolved or dispensed or suspended or
emulsified as an antiseptic, antifungal agents and Sulphur ointment used to treat different skin
infections.
Formula:
Preparation of simple ointment base:
Sl. No. Ingredients Official formula Working formula Required
quantities
1 Wool fat 5gm
2 Hard paraffin 5gm
3 Cetostearyl alcohol 5gm
4 White soft paraffin 85gm 100gm

Sl. No. Ingredients Official formula Working Required quantities

formula

1 Sublimed 10gm
Sulphur
2 Simple ointment 90gm 100gm

Calculation:

Procedure:
Preparation of simple ointment:
 Required quantity of hard paraffin and Cetostearyl alcohol.
 Wool fat and white soft paraffin were incorporated and stirred until all ingredients weremelted.
 The mixture was stirred thoroughly until cooled.
Preparation of Sulphur ointment:
Sublimed Sulphur was triturated and finely shifted through sieve no.85. Required quantity of Sulphur
was taken on ointment base and mix small amount of ointment of simple ointment was gradually added
until homogeneous mass was obtained.
 Direction: Apply as directed.

Use:
 This are used to treat acne Sulfur ointment.
 This are used to treat seborrheric dermatitis and scabies.

Storage: Keep in well closed container and cool place.

SULPHUR OINTMENT I.P

100gm

Compositions:
Wool fat BATCH NO. MFG. DATE:
Hard paraffin
Cetostearyl alcohol
White soft paraffin MFG. LIC. NO.: EXPIRY DATE:
Category: Acne

FOR EXTERNAL USE ONLY.

Use: This are used to treat acne Sulphur ointment and also used to treat seborrheric dermatitis and
scabies.

Storage: Stored in a well closed container dark and cool place and temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Label:

Report:
 Exp. No.-10 Date:
Aim: To prepare and submit 100gm of Cetrimide cream B.P.C.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017; 247
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, water bath, beaker, measuring cylinder etc.
Chemical Required:
Cetrimide, Cetostearyl alcohol, liquid paraffin and purified water.
Principle:
Creams are the semisolid product used for protection of skin. They are also used for medicinal or
beautification as a foundation for other cosmetics and for cleaning action. Thus, creams are for
external use only. The term vanishing is used for those cream and lotions which spread easily and
disappear rapidly when rubbed on the skin.

Formula:
Sl. No. Ingredients Official formula Working Required
formula quantities
1 Cetrimide 0.5gm

2 Cetostearyl alcohol 5gm

3 Liquid paraffin 50gm

4 Purified water 44.5gm 100gm

Calculation:

Procedure:
 Melt the Cetostearyl alcohol on a water bath.
 Add the liquid paraffin and heat to 600C.
 Dissolve the Cetrimide in freshly boiled and cooled purified water and warm to 600C.
 Add the aqueous solution to the oily mixture and stir until cold.
 Transfer the cream into a suitable container, label and dispense.

Storage: Store in a well closed wide mouth containers or in collapsible tubes.

Use: As foundation to other cosmetics and for beautification
Direction: To be applied on dry skin three times a day.
 Label:

CETRIMIDE CREAM B.P.C

100gm
Composition:
Cetrimide
BATCH NO.: MFG. DATE:
Cetostearyl alcohol

Liquid paraffin MFG. LIC NO.: EXPIRY DATE:

Purified water.

Category: Cosmetics

FOR EXTERNAL USE ONLY.

Use: As foundation to other cosmetics and for beautification

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-11 Date:
Aim: To prepare and submit 30gm of Sodium alginate gel.
Reference:
 Pharmacopoeia of India
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker etc.
Chemical Required:
Sodium alginate, Calcium chloride, Coloring agent, purified water
Principle:
A gel is a semi-solid that can have properties ranging from soft and weak to hard and tough. Gels
are defined as a substantially dilute cross-linked system, which exhibits no flow when in the steady-
state. A gel has been defined phenomenologically as a soft, solid or solid-like material consisting of
two or more components, one of which is a liquid, present in substantial quantity.

Formula:

Sl. Ingredients Official Working Required

No. formula formula quantities

1. Sodium 2%w/v
alginate
2. Calcium 5%w/v
chloride
3. Coloring agent q. s
4. Purified water 100ml 30gm

Calculation:

Procedure:
Step 1: Mix the dry, powdered sodium alginate with distilled water.
For a great gel, use 100 ml of distilled water and 1 teaspoon of sodium alginate (this is a 2%
sodium alginate solution).
Step 2: In another container, mix the calcium chloride with distilled water.
Use a heaping teaspoon of calcium chloride in 100 ml of distilled water (this is a 5% calciumchloride
solution)
Step 3: Make a gel by adding dissolved alginate to the calcium solution.
Using a spoon or a dropper, add (i.e., drop or squirt) a little of the sodium alginate solution into the
calcium chloride solution. In an instant, the calcium reacts with the sugar units in the alginate to
pull the long flexible chains of alginate into a gel.

Use: Alginate is used as an emulsifier or stabilizer.

 Storage:
It should be tightly closed and stored out of contact with water.

Label:

SODIUM ALGINATE GEL

30gm

Compositions:
Sodium alginate BATCH NO. MFG. DATE:

Calcium chloride
Colouring agent MFG. LIC. NO.: EXPIRY DATE:
Purified water
Category: Stabilizing
FOR EXTERNAL USE ONLY.
Use: used as an emulsifying, stabilizing, suspending, thickening in
Storage: Stored in a well closed container at a temperature not exceeding 250C
It should be tightly closed and stored out of contact with water
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-12 Date:
Aim: To prepare and submit 30ml of Turpentine Liniment.

Reference:
Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017;164 -165
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Soft soap, camphor, turpentine oil, purified water.
Principle:
Liniments are solution or suspensions or emulsion intended for external application. They are
generally applied with massage. Liniment of turpentine is used externally in a patient suffering from
arthalgia, myalgia, fibrositis, and sprain.

Formula:

Sl. No. Ingredients Official formula Working formula Required quantities

1 Soft soap 9gm

2 Camphor 5gm

3 Turpentine oil 69gm

4 Purified water 1000ml 30ml

Calculation:

Procedure:
 Take the required quantity of soft soap in the mortar and add water in thrice the quantity assoft soap.
 Triturate to make a soapy solution.
 Take the required quantity of oil of turpentine in a dry measure glass and dissolve camphorin it.
 Add this solution drop by drop in the mortar and triturate continuously and rapidly till theprimary
emulsion is formed.
 Add a small quantity of water and transfer it to the previously calibrated round verticallyribbed and
blue and amber colored bottle.
 Adjust to the required volume by adding water, attach the cork and label it.

Use:
Liniment of turpentine is used externally in a patient suffering from arthalgia, myalgia, fibrositis,and
sprain.

Storage:
It should be store in a well closed container dark in a cool place.
 Label:

TURPENTINE LINIMENT
30ml
Composition:
Soft soap BATCH NO. MFG. DATE:
Camphor
MFG. LIC. NO.: EXPIRY DATE:
Turpentine oil
Purified water
Category: Arthalgia
FOR EXTERNAL USE ONLY.
Use: Liniment of turpentine is used externally in a patient suffering from arthalgia, myalgia,
fibrositis, and sprain.
Storage: Stored in a well closed container dark in a cool place and temperature not exceeding
250C
MFG BY: ABCD Batch: Roll No.

Report:
 Exp. No.-13 Date:
Aim: To prepare and submit 30ml of White Liniment BPC.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi,2017;164 -165
 Indian Pharmacopoeia.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Ammonium chloride, Dil. Ammonia Solution, Oleic acid, turpentine oil, purified water
Principle:
Liniments are solution or suspensions or emulsion intended for external application. They are
generally applied with massage. Liniment of turpentine is used externally in a patients suffering from
arthalgia, myalgia, fibrositis and sprain.
Formula:
Sl. No. Ingredients Official Working formula Required quantities
formula
1 Ammoniumchloride 12.5
gm

2 Dil. AmmoniaSolution 45 ml

3 Oleic acid 83.3

ml
4 Turpentine oil 250 ml

5 Purified water 625ml 30ml

Calculation:

Procedure:
 Mix turpentine oil and oleic acid in a bottle.
 Add an equal volume of warm water (50 ºC) to a dilute ammonia solution. Then add thisdilute solution
(in small amount to the oily liquid, shake vigorously after each addition.
 Dissolve the ammonium chloride in the rest of the water and add it to the bottle (in smallamount) and
shake vigorously after each addition.

Use: White Liniment is a rubefacient, which is a substance that warms the skin. It is used for relief
from sciatica. Sprains, lumbago and rheumatoid pains,

Storage: It should be store in a well closed container dark in a cool place.

 Label:
WHITE LINIMENT BPC
30ml
Composition:
Ammonium Chloride BATCH NO. MFG. DATE:
Dil. Ammonia Solution
MFG. LIC. NO.: EXPIRY DATE:
Oleic Acid
Turpentine oil
Purified water
Category: Arthalgia
FOR EXTERNAL USE ONLY.
Use: White liniment is used for the relief of sciatica, sprains, lumbago and rheumatic pains.

Storage: Stored in a well closed container dark in a cool place and temperature not exceeding
250C

MFG BY: ABCD Batch: Roll No.

Report:
 Exp. No.-14 Date:
Aim: To prepare and submit 10gm of Effervescent granules.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 127
 Subrahmanyam C.V.S., Thimmasetty. J, Prabhushankar G.L., Laboratory manual of Pharmaceutics.
Vallabh Publication, Delhi, 2019; 88
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance sieve shaker, China dish etc.
Chemical Required:
Sodium phosphate, sodium bicarbonate, tartaric acid.
Principle:
Effervescent preparation provides effervescence of CO2 gas when added to water by a chemical
reaction between alkali metal carbonates or bicarbonates with tartaric acid or citric acid. This
preparation is intended to be dissolved in water before it is being taken orally. The CO2 gas is released
as a result of acid-base reaction. The preparation is advised to be taken while effervescence.

Formula:
Sl. No. Ingredients Official formula Working Required quantities
formula
1 Sodium phosphate 0.9gm
2 Sodium bicarbonate 2.1gm
3 Tartaric acid 1.1gm
4 Citric acid 0.7gm 10gm

Calculation:

Procedure:

 Citric acid is mixed with sodium phosphate and tartaric acid.

 Add sodium bicarbonate to the above mixture and mix it gently.
 The final powdered mixture is placed in a China dish previously heated on water bath.
 Stir the mixture with the help of a spatula constantly still it becomes damp mass.
 Pass damp mass through sieve number 8.
 Dry granules at a room temperature not exceeding 540C.
 Pass dry granules through appropriate sieve.
 Pack dry uniform sized granules in a wide mouthed bottle.

Dose: Each 5g contains sodium phosphate 1g.

 Storage: Stored in air tight container in a cool place,

Use: Saline purgative and mild diuretic.

Label:

EFFERVESCENT GRANULES
10gm
Composition:
Sodium phosphate BATCH NO. MFG. DATE:
Sodium bicarbonate
Tartaric acid
MFG. LIC. NO.: EXPIRY DATE:
Citric acid
Category: Saline purgative and Mild diuretic
FOR INTERNAL USE ONLY.
Use: Saline purgative and Mild diuretic
Storage: Stored in a well closed air tight container in a cool place and temperature not exceeding
250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-15 Date:
Aim: To prepare and submit 30gm of Dusting powder.
Reference:
 Mehta R.M., Dispensing Pharmacy, Vallabh Prakashan, New Delhi, 2017; 115
Requirements:
Apparatus Required: Mortar & pestle, weigh balance, sieve shaker etc.
Chemical Required: Purified talc, starch, zinc oxide
Principle:
Dusting powders are usually mixtures of two or more substances in fine powder intended for external
use. Starch possess binding as well as good flow property which helps the powder to flow easily,
spread uniformly and cling to the skin on application. Talc is natural mineral substance zinc oxide is
protectant.
Formula:
Sl. No. Ingredients Official formula Working formula Required quantities

1 Purified talc 1gm

2 Starch 0.5gm

3 Zinc oxide 0.5gm 30gm

Calculation:

Procedure:
 Weigh the required quantity of purified talc and zinc oxide.
 Mix zinc oxide with starch and incorporate purified talc.
 Mix thoroughly and pass the mixed powder through a sieve no.120 to remove gritty particles.
 After sieving whole of the powder must be again slightly mixed.
 Pack the powder to protect it from air, moisture and contamination.
Storage: Store in a well closed container and should be kept in a cool place.
Category: Antiseptic dusting powder.
Caution: Do not apply on raw (or) weeping surface.
Direction: For external use only.
Use: Antiseptic.
Label:
DUSTING POWDER
30gm
Composition:
Purified talc BATCH NO. MFG. DATE:
Starch
Zinc oxide MFG. LIC. NO.: EXPIRY DATE:
Category: Antiseptic
FOR EXTERNAL USE ONLY.
Use: Antiseptic
Storage: Store in a well closed container and should be kept in a cool place.
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-16 Date:
Aim: To prepare and submit 10 ml sodium chloride injection I.P
Reference:
 Gupta A.K., Jain V.K., Pharmaceutics-I Practical Note Book, CBS Publishers & Distributors
Pvt.Ltd.2020; 85
 Dr. Kastur P.V., Gokhale S.B., Parakh S.R., Hasan S.A. Practical Pharmaceutics- 1, Nirali Prakashan,
August 2019,26th Edition.Mumbai;10.9
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Sodium chloride and sterile water for injection I.P
Principle:
Sodium Chloride Injection 0.9% is used to replace lost body fluids and salts. Other medicines
which are given by injection or by a drip may be diluted with Sodium Chloride Injection 0.9%.
Sodium Chloride Injection 0.9% can also be used as a sterile irrigation solution.

Formula:

Sl. No. Ingredients Official formula Working formula Required

quantities
1 Sodium chloride 0.9% w/v
2 Sterile water for q. s 10ml
injection I. P

Calculation:

Procedure:
Accurately weighed quantity of pure sodium chloride is dissolve in freshly distilled pyrogen free
sterile water. The solution is then filtered and filled in ampoules taking precautions to minimize
bacterial contamination. Alternatively, the solution may be filled in clean dry infusion bottles and
rubber bung is used to close the infusion bottle. Bottles are then placed in an autoclave at 121 00 and
15 psi pressure for 30 minutes.

Dose: No specific dose since it is used as a solvent.

Uses: It is used as an absorbent and transport nutrients. It maintains blood pressure and the right
balance of fluid.

Storage: It should be stored in glass ampoules.

 Label:
SODIUM CHLORIDE INJECTION I.P

10ml

Composition:

Sodium chloride BATCH NO.: MFG. DATE:

Sterile water for injection I. P

Category: Isotonic vehicle MFG. LIC NO.: EXPIRY DATE:

FOR INTERNAL USE ONLY.

Use: It is used as a absorb and transport nutrients

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-17 Date:
Aim: To prepare and submit 10 ml Calcium gluconate injection I.P
Reference:
 Gupta A.K., Jain V.K., Pharmaceutics-I Practical Note Book, CBS Publishers & Distributors
Pvt.Ltd.2020; 85
 Dr. Kastur P.V., Gokhale S.B., Parakh S.R., Hasan S.A. Practical Pharmaceutics- 1, Nirali Prakashan,
August 2019, 26th Edition.Mumbai;10.9
 Indian Pharmacopoeia.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel etc.
Chemical Required:
Calcium Gluconate, Calcium D Saccharate, Water for Injection
Principle: Calcium Gluconate injection is a sterile solution of calcium gluconate in water for injection.
Not more than 5% of calcium gluconate may be replaced with a suitable calcium salt as a stabilizing
agent.
Formula:

Sl. Ingredients Official Working formula Required quantities

No. formula
1 Calcium Gluconate 9.65gm
2 Calcium D saccharate 0.35gm
3 Sterile water for 100ml 10ml
injection I. P

Calculation:

Procedure:

Weigh the desired amount of calcium gluconate and calcium D saccharate. At first mix the calcium
gluconate and water for injection in presence of heat. Then calcium D saccharate is dissolved in above
solution. Then cool it and filter it.

Dose: 1 to 2 gm
Uses: Treat conditions arising from calcium deficiencies such as hypocalcemic tetany,
hypocalcaemia related to hyperparathyroidism, and hypocalcaemia due to rapid growth or pregnancy.

Storage: It should be store in glass ampoules.

 Label:

CALCIUM GLUCONATE INJECTION I.P

10ml

Composition:

Calcium Gluconate BATCH NO.: MFG. DATE:

Calcium D saccharate

Sterile water for injection I. P MFG. LIC NO.: EXPIRY DATE:

Category: Calcium replenisher

FOR INTERNAL USE ONLY

Use: Treat conditions arising from calcium deficiencies

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-18 Date:
Aim: To prepare and submit 10 Tetracycline Capsule I.P
Reference:
 Dr. Kastur P.V., Gokhale S.B., Parakh S.R., Hasan S.A. Practical Pharmaceutics.
 Nirali Prakashan, August 2019, 26th Edition.Mumbai;8.3-8.4
 Indian Pharmacopoeia.
Requirements:
Apparatus Required: Mortar & pestle, weigh balance and spatula.
Chemical Required: Tetracycline, Starch,Talc.
Principle:
Capsule may contain one or more medicaments with or without excipients. The content of the capsule
may be solid, liquid or paste. If quantity of the drug or drug is insufficient to fill the capsulethen
diluents is used to increase the bulk. After mixing the drug with diluents appropriate size of a capsule
is selected for filling.

Formula:

Sl. No. Ingredients Official formula Working Required

formula quantities
1 Tetracycline 250mg

2 Starch 25mg

3 Talc 25mg For 10 tabs

Calculation:

Procedure:
 Weigh the required quantity of drug and other excipients.
 Moisture content should be less than 1.5%.
 Starch should be dried and sieved through 100*, moisture less than 1.5%.
 Talcum should be dried and sieved through 100S, moisture less than 1%.
 Mix all the ingredients uniformly using mortar and pestle.
 Empty capsule shells of number "0" is selected and for filling the content in capsule shell.
 Store capsules in air tight container.
Use: Antibacterial
Storage: Capsule should be stored in cool place with controlled humidity.

Dose: Tetracycline is taken by mouth as a capsule or liquid, typically two to four times a day for seven
to 14 days.

Label:
TETRACYCLINE CAPSULE I.P

Composition:Tetracycline Starch

Talc BATCH NO.: MFG. DATE:

MFG. LIC NO.: EXPIRY DATE:

Category: Antibacterial

FOR INTERNAL USE ONLY.

Use: Antibacterial

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-19 Date:
Aim: To prepare and submit 10 Paracetamol Tablet.
Reference:
 Dr. Kastur P.V., Gokhale S.B., Parakh S.R., HASAN S.A. Practical Pharmaceutics- 1, Nirali
Prakashan, August 2019,26th Edition.Mumbai;9.11
 Indian Pharmacopoeia.
Requirements:
Apparatus Required:
Mortar and pestle, beaker, sieve No 10, tablet punching machine, hot air oven
Chemical Required:
Paracetamol, lactose, dry starch, magnesium stearate, talc.
Principle:
Paracetamol has analgesic and antipyretic properties but it has no useful anti- inflammatory properties.
Paracetamol is readily absorbed from the gastrointestinal tract. Paracetamol is categorized under BCS
classification ii tablets are solid dosage forms containing one or more drugs with or without excipients,
prepared by compression. It provides greatest dose precision and least content variability. Inert
materials employed in addition to active ingredients are collectively called tablet additives.
Formula:

Sl. No. Ingredients Official Working Required

formula formula quantities
1 Paracetamol 125mg
2 lactose 375mg
3 Starch 48mg
4 Talc 40mg
5 Magnesium Stearate 12mg
6 5% starch Q.s.

Calculation:
Procedure:
The tablets were granulated using wet granulation method as follows.
Paracetamol, lactose and half the quantity of starch were weighed and mixed thoroughly. It was
granulated using 5% starch mucilage as binding agent and passed through no.10 mesh screen. The
obtained the granules were dried at 55ᵒc for 1 hr. After drying, dry screening was done using no.22
mesh screen. The rest of the starch powder along with talc and magnesium stearate were added and
mixed. These granules were compressed into tablets on a 16station cad mach rotary tablet machine
(12mm).
Use: Analgesic, antipyretic, anti- rheumatic.

Dose: 650mg to 1000 mg every 4 hour not exceeding 4000mg per day.

Label:
 PARACETAMOL TABLET IP
Composition:

Paracetamol BATCH NO.: MFG. DATE:

Lactose Starch

Talc MFG. LIC NO.: EXPIRY DATE:

Magnesium Stearate

Category: Antipyretic
FOR INTERNAL USE ONLY.
Use: Analgesic, antipyretic, anti- rheumatic

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-20 Date:
Aim: To prepare and submit 20ml of shampoo.

Reference:
Dr. Kastur P.V., Gokhale S.B., Parakh S.R., Hasan S.A. Practical Pharmaceutics-1,NiraliPrakashan,
August 2019,26th Edition.Mumbai;7.6
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker etc.

Chemical Required:
Coconut oil, Castor oil, Potassium hydroxide, Glycerol, Perfume, Borax, Purified water

Principle:
The function of shampoo is to clean hairs and to remove dirt, dust and sebum from the surface. It also
leaves hair in soft, lustrous and manageable condition. If soap is used for cleaning the hair afterdrying
gives electrostatic fly while combing. Shampoo removes this drawback and leaves the conditioning
effect.
Formula:
Sl. Ingredients Official formula Working formula Required
No. quantities
1 Coconut oil 18% v/v
2 Castor oil 4%v/v
3 Potassium hydroxide 5.3%w/v
4 Glycerol 4%v/v
5 Perfume 0.2%v/v
6 Borax 0.5%w/v
7 Purified water 68%v/v 20ml

Calculation:

Procedure:

In a beaker heat coconut oil, castor oil with potassium hydroxide and little quantity of water-on- water
bath. In the remaining water add glycerol. Borax and perfume mix together. Mix both the liquid to
form clear solution.

Use: The function of shampoo is to clean hairs and to remove dirt, dust and sebum from thesurface
Storage: Stored in well closed air tight container.
 Label:

SHAMPOO

20ml
Composition:
Coconut oil
Castor oil
Potassium hydroxide
Glycerol BATCH NO.: MFG. DATE:
Perfume
Borax
Purified water
MFG. LIC NO.: EXPIRY DATE:
Category: Cleaning hair
FOR EXTERNAL USE ONLY.
Use: It is used as a clean the hairs and to remove dirt, dust and sebum from the surface

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-21 Date:
Aim: To prepare and submit 30gm of cold cream.

Reference:
 Gupta A.K., Jain V.K., Pharmaceutics-I Practical Note Book, CBS Publishers & Distributors
Pvt.Ltd.2020; 65
 Dr. KASTUR P.V., GOKHLE S.B., PARAKH S.R., HASAN S.A. Practical Pharmaceutics-1, Nirali
Prakashan, August 2019, 26th Edition.Mumbai;6.3

Requirements:
Apparatus Required:
Mortar & pestle, weigh balance sieve shaker, China dish, water bath.

Chemical Required:
White bees wax, liquid paraffin, borax, perfume, purified water

Principle:
Cream are the semisolid product used for protection of skin. for medicinal or beautification as a
foundation for other cosmetics and for cleaning action. Thus, creams are for external use only the cold
cream is used as protected to skin. Formula contains borax and bee wax. Borax soap is obtained by
free in type bee wax and borax.

Formula:

Sl. No. Ingredients Official formula Working Required quantities

formula
1 White bees wax 20gm
2 Liquid paraffin 60gm
3 Borax 1gm
4 Perfume adequate
5 Purified water 19ml 30gm

Calculation:

Procedure:
Bee wax and liquid paraffin are heated up to 700C on water bath to obtain molten mass. Dissolve
borax in water and raise the temperature to that of waxy phase. Then gradually add the solution
with constant storing to obtain the cream. Stirring should be vigorous initially but then be slowed
down to avoid air entrapping. Perfume it suitably and then pours in suitable container.

Storage:
Stored in well closed air tight container to avoid dehydration. Collapsible tubes may also be used.

Use: It is used as emollient and protect to the skin.

Label:
 COLD CREAM

30gm
Composition:

White bees wax BATCH NO.: MFG. DATE:

Liquid paraffin

Borax

Perfume MFG. LIC NO.: EXPIRY DATE:

Purified water
Category: Emollient & Protective

FOR EXTERNAL USE ONLY.

Use: It is used as emollient and protect to the skin.

Storage: Stored in a well closed container at a temperature not exceeding 250C

MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-22 Date:
Aim: To prepare and submit 20gm lipsticks.

Reference:
 Dr. KASTUR P.V., GOKHLE S.B., PARAKH S.R., HASAN S.A. Practical Pharmaceutics-1, Nirali
Prakashan, August 2019,26th Edition.Mumbai;7.4
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker etc.
Chemical Required:
Carnauba wax, Bee wax, lanolin, Cetyl alcohol, carmine, perfume, Castor oil
Principle:
Lipsticks are normally prepared with oil and wax base, stiff enough to form a stick with red staining
dye or pigment. Perfume is incorporated with oil for suitably flavors the sticks. These are prepared by
moulding and finally kept in the lipsticks case.

Sl. Ingredients Official formula Working Required quantities

No. formula
1 Carnauba wax 10% w/v
2 Bee wax 15%w/v
3 Lanolin 5%w/v
4 Cetyl alcohol 5%w/v
5 Carmine adequate
6 Perfume adequate
7 Castor oil 65%w/v 20gm

Formula:

Calculation:

Procedure:
Mix carmine in castor oil. Melt all the waxes on the water bath at about 70 0C. Heat castor oil to the
same degree of temperature and mix it with the melted waxes. Lubricate the mould using lubricating
fluid. Pour the molten mass in the mould. Allow it to solidify and then cut the surface using sharp
knife. Remove the sticks from the mould and fit it in the lipstick case.

Use: Apply with light pressure to the pre-moistened lips.

Storage: Stored in well closed air tight container.

Label:
 LIPSTICKS
20gm
Composition:
Carnauba wax
Bee wax BATCH NO.: MFG. DATE:
Lanolin
Cetyl alcohol
Carmine MFG. LIC NO.: EXPIRY DATE:
Perfume
Castor oil
Category: Pre-moistened lips
FOR EXTERNAL USE ONLY.
Use: Apply with light pressure to the pre-moistened lips.
Storage: Stored in a well closed container at a temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-23 Date:
Aim: To prepare and submit 30gm of vanishing cream.

Reference:
 Gupta A.K., Jain V.K., Pharmaceutics-I Practical Note Book, CBS Publishers & Distributors
Pvt.Ltd.2020; 55
 Dr. KASTUR P.V., GOKHLE S.B., PARAKH S.R., HASAN S.A. Practical Pharmaceutics-1, Nirali
Prakashan, August 2019,26th Edition.Mumbai;6.3

Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, water bath, beaker, measuring cylinder etc.

Chemical Required:
Stearic acid, potassium hydroxide, Glycerine, perfume, purified water

Principle:
Creams are the semisolid product used for protection of skin. For medicinal or beautification as a
foundation for other cosmetics and for cleaning action. Thus, creams are for external use only. The
term vanishing is used for those cream and lotions which spread easily and disappear rapidly when
rubbed on the skin.
Formula:

Sl. No. Ingredients Official formula Working Required

formula quantities
1 Stearic acid 15% w/v
2 Potassium 0.7% w/v
hydroxide,
3 Glycerine, 8%w/v
4 Perfume, adequate
5 Purified water 100% 30gm

Calculation:

Procedure:
 Dissolve potassium hydroxide in little quantity of water.
 Add Stearic acid to it and heat until it is melted.
 Mix Glycerine with the remaining quantity of water and raise the temperature of the mixtureequal to
the other phase.
 With slow but continuous trituration mix both the phases to form a smooth cream.
 Perfume it suitably.

Storage: Store in a well closed wide mouth containers or in collapsible tubes may also use.

Use: As foundation to other cosmetics and for beautification.

Label:
 VANISHING CREAM
30gm
Composition:
Stearic acid Potassium
hydroxide,Glycerine, BATCH NO.: MFG. DATE:

Perfume,
MFG. LIC NO.: EXPIRY DATE:
Purified water

Category: Cosmetics

FOR EXTERNAL USE ONLY.

Use: As foundation to other cosmetics and for beautification
Storage: Stored in a well closed container at a temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
 Exp. No.-24 Date:
Aim: To prepare and submit 20gm of face powder.

Reference:
 Dr. KASTUR P.V., GOKHLE S.B., PARAKH S.R., HASAN S.A. Practical Pharmaceutics-1,Nirali
Prakashan, August 2019, 26th Edition. Mumbai; 7.1
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, sieve shaker etc.

Chemical Required:
Talc, kaolin, Chalk precipitated, Zinc stearate, Zinc oxide, Perfume and colour

Principle:
It is a skin cosmetic. In order to impart natural, fresh look to the facial skin, face powder is used. Itis
applied with powder puff. The preparation has ability to complement skin colour by imparting avelvet
like finish, it also masks the excessive shine of the skin due to secretion of sebaceous and sweat glands.

Formula:

Sl. No. Ingredients Official formula Working formula Required

quantities
1 Talc 75%w/v
2 Kaolin 5%w/v
3 Chalk precipitated 5%w/v
4 Zinc stearate 5%w/v
5 Zinc oxide 10%w/v
6 Perfume and colour q. s 20gm

Calculation:

Procedure:
All the solid ingredients are finely powdered and sieve to remove any greety particles. Perfume is
mix with precipitated chalk and macerated. Then all the ingredients are mixed as per ascending order
of their weight. Ribbon mixer is used for large scale production. The powder is then transferin the
plastic or tin container with sealed perforated mouth, closed with air tight lid.

Uses: As a cosmetic for facial skin

Storage: Stored in well closed air tight container.

 Label:

FACE POWDER
20gm
Composition:
Talc
Kaolin
BATCH NO.: MFG. DATE:
Chalk precipitated
Zinc stearate
MFG. LIC NO.: EXPIRY DATE:
Zinc oxide
Perfume and colour
Category: Cosmetic

FOR EXTERNAL USE ONLY.

Use: As a cosmetic for facial skin
Storage. Stored in a well closed container at a temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Report:
Exp. No.-25 Date:
Aim: To prepare and submit 20gm of Toothpaste.
Reference:
1. Mithal BM, Saha RN, A Handbook of cosmetics, 1st Edn, Vallabh Prakashan, 2000
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, Beaker, Pipette etc.

Chemical Required:
Di calcium Phosphate, Sodium Lauryl Sulphate, PEG, Glycerine. Sodium saccharine, Gumtragacanth,
Peppermint oil, water

Principle:
Dentifrices such as toothpastes, tooth powders and tooth gels are meant for the cleaning the surfaceof
the teeth by removing the food debris and plaque adhered to surface of the teeth which is the main
cause for tooth problems.

Formula:

Sl. No. Ingredients Official formula Working formula Required

quantities
1 Di calcium 45gm
Phosphate
2 Sodium Lauryl 1.2gm
Sulphate
3 PEG 5.9gm
4 Glycerine 30gm
5 Sodium saccharine 0.5gm
6 Gum tragacanth 2gm
7 Peppermint oil q. s
8 Water q. s up to 100gm 20gm

Calculation:

Procedure:
Mix gum tragacanth and humectants with water. Add di calcium phosphate with above mixture.
Flavor and SLS were gently added with stirring. Now toothpaste is ready and ready to go for labeling.

Uses: Cleaning the surface of the teeth

Storage: Stored in well closed air tight container.

 TOOTHPASTE
20gm
Composition:
Di calcium Phosphate,

Sodium Lauryl Sulphate, BATCH NO.: MFG. DATE:

PEG,

Glycerine. MFG. LIC NO.: EXPIRY DATE:

Sodium saccharine,

Gum tragacanth,

Peppermint oil,

water

Category: Dentifrices

FOR INTERNAL USE ONLY.

Use: Cleaning the surface of the teeth
Storage: Stored in a well closed container at a temperature not exceeding 250C
MFG BY: ABCD Batch: Roll No.:

Label:

Report: