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DIGITAL
VERSION
Included
DIALYSIS THERAPY
HANDBOOK OF
DIALYSIS THERAPY
Notice
Practitioners and researchers must always rely on their own experience and knowledge in evaluating
and using any information, methods, compounds, or experiments described herein. Because of rapid
advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages
should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors,
or contributors for any injury and/or damage to persons or property as a matter of products liability,
negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas
contained in the material herein.
This book is dedicated to my wife, Kushi Mehrotra, who has stood patiently by
my side for 29 years, to our two children, Kunaal and Ria, who have grown into
amazing young adults in the blink of an eye, and to my parents, Trijugi and
Kamini Mehrotra, who are no longer with us but forever in our hearts.
Rajnish Mehrotra, MD, MS
vii
viii Contributors
Scott Bieber, DO
Physician David Bushinsky, MD
Nephrology Professor of Medicine and of Pharmacology and Physiology
Kootenai Health, Coeur d’Alene Medicine
ID University of Rochester School of Medicine and Dentistry,
United States Rochester
NY, New York
United States
Contributors ix
Yeoungjee Cho, MBBS (Hons), FRACP, PhD Stephanie L. Donahue, MSN, FNP-BC
Consultant Nephrologist Nurse Practitioner Medicine and Behavioral Health
Associate Professor of Medicine, University of Queensland The Rogosin Institute New York, New York
Clinical Trialist (Australian Kidney Trials Network) NY, United States
Department of Nephrology
Division of Medicine
Metro South Health Ramanath Dukkipati, MD
Princess Alexandra Hospital Associate Professor of Medicine
Brisbane, QLD Nephrology and hypertension
Australia Harbor-UCLA Medical Center, Torrance
CA
United States
William R. Clark, MD
Professor of Engineering Practice
Davidson School of Chemical Engineering Claire Dunphy, PhD
Purdue University, W Lafayette Postdoctoral Fellow
IN Pediatrics
United States Icahn School of Medicine at Mount Sinai
New York, NY
John H. Crabtree, MD United States
Visiting Clinical Faculty
Division of Nephrology and Hypertension
Harbor-University of California Los Angeles Medical Mohamed Elbokl, MBBCH
Center, Torrance Clinical Fellow
CA Nova Scotia Health Authority
United States Nephrology
Dalhousie University
Halifax, NS
Daniel Cukor, PhD Canada
Director
Behavioral Health
The Rogosin Institute, New York Fabrizio Fabrizi, MD
NY Staff Nephrologist
United States Division of Nephrology
Maggiore Policlinico Hospital and Ca’ Granda IRCCS
Foundation, Milano
Serpil Muge Deger, MD, FISN Italy
Associate Professor
Department of Nephrology
Dokuz Eylul University Faculty of Medicine Mohammed K. Faizan, MD
Izmir, Turkey Associate Professor
Department of Pediatrics
The Warren Alpert Medical School of Brown University,
Lucia Del Vecchio, MD Providence, RI, United States
Department of Nephrology and Dialysis, Sant’Anna Division Director
Hospital, ASST Lariana Pediatric Nephrology
Como Hasbro Children’s Hospital, Providence
Italy RI, United States
Alonso R. Diaz, MD
Nephrology Fellow
Division of Nephrology, Department of Internal Medicine
University of California, Davis School of Medicine,
Sacramento
CA
United States
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Contributors xi
Molly Fisher, DO
Assistant Professor of Medicine Ashley M. Gefen, MD
Medicine Fellow
Montefiore Medical Center, Bronx Department of Pediatrics, Division of Nephrology
NY Cohen Children’s Medical Center
United States New Hyde Park, NY
United States
Sharlene Anuska Greenwood, PhD, BSc Sarbjit Vanita Jassal, MD, MB, MRCP(UK),
Consultant Physiotherapist FRCPC
Renal Staff Nephrologist and Director, Geriatric Dialysis
King’s College Hospital, London Program
United Kingdom Division of Nephrology
Honorary Senior Lecturer University Health Network, Toronto
Renal Sciences ON
King’s College London, London Canada
United Kingdom Professor
Medicine
University of Toronto, Toronto
Dieter Haffner, MD ON
Professor Canada
Pediatric Kidney, Liver and Metabolic Diseases
Hannover Medical School, Hannover
Lower Saxony Kirsten L. Johansen, MD
Germany Professor of Medicine
Department of Medicine
University of Minnesota School of Medicine
Rainer Himmele, MD, MSSH Director
Head of Global Medical Information & Education Division of Nephrology
Fresenius Medical Care Hennepin Healthcare
Charlotte Minneapolis, MN
NC United Sates
United States
Robin A. Kremsdorf, MD
Paul L. Kimmel, MD, MACP, FRCP, FASN Assistant Professor
Clinical Professor of Medicine Department of Pediatrics
Emeritus George Washington University The Warren Alpert Medical School of Brown University
Washington Providence, RI
DC United States
United States
Martin Kreuzer, MD
Alan S. Kliger, MD Department of Pediatrics II
Clinical Professor of Medicine Essen University Hospital, Essen
Medicine North Rhine-Westphalia
Yale School of Medicine, New Haven Germany
CT
United States
Mahesh Krishnan, MD, MPH, MBA, FASN
Group Vice President
Timothy Koh Jee Kam, MBBS, MMed(Int Med), Research and Development
MRCP(UK) DaVita Venture Group, Washington
Senior Consultant DC
Renal Medicine United States
Tan Tock Seng Hospital, Singapore
Singapore
Martin K. Kuhlmann, MD
Department of Internal Medicine—Nephrology
Berfu Korucu, MD Vivantes Klinikum im Friedrichshain, Berlin
Nephrology and Hypertension Germany
Vanderbilt University School of Medicine,
Nashville
TN Danica Lam, BASc, MD
United States Division of Nephrology
Nephrology Humber River Hospital, Toronto
Gazi University Faculty of Medicine, Ankara ON
Turkey Canada
xiv Contributors
Francesco Locatelli, MD
Past Director MD Kevin J. Martin, MB, BCh, FASN
Department of Nephrology and Dialysis Professor of Internal Medicine
A. Manzoni Hospital ASST Lecco Division of Nephrology
Lecco Saint Louis University, Saint Louis
Italy MO
United States
Joseph B. Lockridge, MD
Associate Professor Nicola Matthews, FRCP(C)
Nephrology Staff Nephrologist
Oregon Health and Sciences University, Portland Division of Nephrology
OR Mackenzie Health
United States Richmond Hill, ON
Medical Director for Kidney Transplantaion Canada
Department of Hospital and Specialty Medicine
VA Portland, Portland
OR Juliet Mayes, BSc (Hons) Physiotherapy
United States Specialist Renal Physiotherapist
Therapies Department
King’s College Hospital, London
Charmaine E. Lok, BSc(PT), MD, MSc, FRCPC United Kingdom
Professor of Medicine
Department of Medicine, Division of Nephrology
University of Toronto, Toronto Ian E. McCoy, MD, MS
ON Assistant Professor
Canada Department of Medicine, Division of Nephrology
University of California, San Francisco
San Francisco, CA
Etienne Macedo, MD, PhD United States
Assistant Professor
Medicine
UCSD, San Diego Christopher W. Mcintyre, MD, PhD
CA Professor of Medicine, Medical Biophysics
United States and Pediatrics
Department of Medicine
University of Western Ontario, London
John D. Mahan, MD ON
Professor of Pediatrics Canada
Department of Pediatrics Robert Lindsay Chair of Dialysis Research
Nationwide Children’s Hospital/The Ohio and Innovation
State University College of Medicine University of Western Ontario, London, ON
Columbus, OH Canada
United States
Contributors xv
Giorgina B. Piccoli, MD
Alejandra Orozco-Guillén, MD, PhD Néphrologie et Dialyse
Nephrologist Centre Hospitalier Le Mans
Unit Intensive Adult Care Le Mans
National Institute of Perinatology, Mexico City France
Mexico
Internal Medicine
Unit Intensive Adult Care Joanne D. Pittard, MS, RN
National Institute of Perinatology, Mexico City Nursing Education Consultant
Mexico Hemodialysis, Inc.
Professor Emerita of Allied Health
Glendale College
David I. Ortiz-Melo, MD Glendale, CA
Assistant Professor United States
Medicine-Nephrology
Duke University, Durham
NC Connie M. Rhee, MD, MSc
United States Associate Professor of Medicine
Department of Medicine, Division of Nephrology,
Hypertension and Kidney Transplantation
Biff F. Palmer, MD University of California Irvine School of Medicine,
Professor of Internal Medicine Orange
Internal Medicine CA
University of Texas Southwestern Medical Center, Dallas United States
TX
United States
Professor of Internal Medicine Ezequiel Ridruejo, MD
Medicine Chief
Univserity of Texas Southwestern Medical Center, Dallas Hepatology Section, Department of Medicine
TX Centro de Educación Médica e Investigaciones Clínicas
United States Norberto Quirno “CEMIC”, Ciudad Autónoma de
Buenos Aires
Argentina
Suetonia C. Palmer, MB, ChB, PhD
Medicine
University of Otago Christchurch, Christchurch Claudio Rigatto, MD, MSc
New Zealand Associate Professor of Medicine
University of Manitoba, Winnipeg
MB
Patrick S. Parfrey, MD, FRCPC, FRSC Canada
Distinguished University Professor
Faculty of Medicine
Memorial University of Newfoundland, St. John’s
NL
Canada
Contributors xvii
III
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