1. Identify the image and its vitamin deficiency.

a. Niacin

b. Copper

c. Iron

d. Selenium

2. A child presents with complaints of urine turning black standing. What is the diagnosis?

a. Homocystinuria

b. Tyrosinemia

c. Alkaptonuria

d. Maple syrup urine disease

3. Complex IV inhibitors:

a. Cyanide

b. Carbon dioxide

c. Oligomycin

d. Qubain
4. A patient has swelling in metacarpophalangeal joints. Serum uric acid levels was raised.
Doctor prescribed medicine for same. The medicine act by inhibiting which enzyme

a. Thymidylate synthase

b. Xanthine oxidase

c. ADA (Adenosine deaminasae)

d. HGPRT

5. Vitamin deficiency causes tingling sensation:

a. Vitamin A

b. Vitamin B1

c. Folic acid

d. Vitamin B6

6. Menke's kink hair disease is due to:

a. P53 defect

b. Copper excess

c. Copper deficiency

d. Zinc deficiency

7. A patient came to OPD with complaints of diarrhea, dermatitis and dementia. It was also
found that he was a maize eater. Which of the following could be most prob- ably deficient?

a. Thiamin

b. Riboflavin

c. Niacin

d. Biotin
8. A 40-year-old female patient came to OPD with features of anemia. She had undergone
subtotal gastrectomy few months back. General examination showed the following changes in
the tongue as shown in the image. Which of the following vitamin is responsible for this?

a. Vitamin A

b. Vitamin B12

c. Vitamin C

d. Vitamin B2

9. Which of the following condition is true about fed state?

a. Increase in insulin level and decrease in glucagon level

b. Increase in glucagon level and decrease in insulin level

c. Both insulin and glucagon levels decrease

d. Only insulin levels increase

10. Patient who is a chronic alcoholic has signs of B1 defi- ciency. Which of the following is the
marker for vitamin B1 deficiency?

a. RBC transketolase activity

b. RBC glyceraldehyde reductase activity

c. Homocysteine activity

d. Pyridoxal 5'-phosphate
11. A 70-year-old male has bruising under the eyes. Which of the following vitamin deficiency
leads to easy bruising and bleeding gums?

a. Vitamin B12

b. Vitamin B2

c. Vitamin B6

d. Vitamin C

12. All of the following are contraindication for breastfeeding: EXCEPT?

a. HIV mother

b. Mother on radiotherapy

c. Galactosemic child

d. CMV infection

13. Cholesterol is synthesized from:

a. Acetyl CoA

b. Malonyl CoA

c. Oxaloacetate

d. Bile acid

14. Glucagon activates all; EXCEPT:

b. Lipolysis

a. Gluconeogenesis

c. Ketone body synthesis

d. Glycolysis
15. Thermogenin is present in:

a. Mitochondria

b. Cytoplasm

c. Lysosomes

d. Peroxisomes

16. Enzyme deficient in Gaucher's disease:

a. Beta galacto cerebrosidase

b. Glucose 6 phosphate

c. Glucose 6 phosphatase

d. Gluco cerebrosidase

17. Fat sugar baby is seen in:

a. Diabetes

b. Kwashiorkor

c. Marasmus

d. Hypothyroidism

18. Dash DIET includes the following food; EXCEPT: (Most Recent Question June/Dec 2021)

a. Rich in potassium

b. Rich in calcium

c. Rich in sodium

d. Rich in magnesium

19. The micronutrient that is deficients after ileal resection:

a. Folate
b. B12

c. Iron

d. Copper

20. A vegetarian patient presents with anemia and hyper segmented neutrophil. The most
probable diagnosis is:

a. Anemia of chronic disease

b. Iron deficiency anemia

c. Megaloblastic anemia

d. Sideroblastic anemia

21. Which of the following explains the role of vitamin D metabolism?

a. Conversion of cholecalciferol to 25 OH choleca

b. Conversion of 25 OH cholecalciferol to calciton

c. Conversion of 25 OH cholecalciferol to 2423

d. Conversion of 7 dehydro cholesterol to cholecal

22. Which of the following enzyme deficiency is to cause classical galactosemia in infants:

a. GALT (galactose 1 phosphate uridyl transferred)

b. Galactokinase

c. UDP galactose 4 epimerase

d. Glucose 6 phosphatase

23. The subcellular organelle which is associated with viruses and bacteria is:

a. Peroxisome

b. Mitochondria
c. Lysosome

d. Golgi apparatus

24. Which of the following has low glycemic index?

a. Potato

b. Watermelon

c. Papaya

d. Sweetcorn

25. Severe combined immune deficiency is seen in:

a. HGPRTase deficiency

b. ADA deficiency

c. MCAD deficiency

d. Purine nucleoside phosphorylase deficiency

26. Which of the following is considered as universal n donor in biochemical reactions?

a. SAM

b. PAPS

c. Methyl cobalamin

d. Methionine

27. Which vitamin deficiency will lead to the following

b. Vitamin B2

c. Vitamin B3

d. Vitamin C

28. A patient with intellectual disability was found to have hyperuricemia. Self-mutation
behaviour was also noticed. Which of the following enzyme is deficient?

a. Alpha galactosidase A

b. Glucocerebrosidase

c. HGPRT
d. Sphingomyelinase

29. Which of the following amino acid is excreted in urine in maple syrup urine disease?

a Tryptophan

b. Phenylalanine

c. Leucine

d. Arginine

30. Hormones that regulate serum calcium levels:

a. Calcitonin, Vitamin D, PTH

b Thyroid, Vitamin D, PTH

c. Calcitonin, Vitamin B

d. Vitamin D, Vitamin C, Vitamin E

31. A patient has macrocytic anemia and high homocysteine levels. His methyl malonyl CoA
levels are normal. What is the diagnosis?

a. Vitamin B6 deficiency

b. Vitamin B9 deficiency

c. Vitamin B12 deficiency

d. Anemia of chronic disease

32. Glutathione peroxidase contains which metal?

a. Selenium

b. Copper

c. Zinc

d. Manganese
33. A patient having fatigue and weakness. On examination, his Hb was low, iron levels were
low. Patient noted that his wound healing is delayed since last 1 year. Which vitamin deficiency
is possible in this patient?

a. Vitamin C

b. Vitamin A

c. Vitamin B12

d. Vitamin B2

34. Fats are stored in which of the following forms in

a. Fatty acid

b. Cholesterol

c. TGs

d. Cholesterol esters

38. Which of the following is underlying cause of xeroderma pigmentosa development?

a. Base excision repair

b. Nucleotide excision repair

c. Mismatch repair

d. Homologous recombination

36. Enzyme deficiency in Von gierke disease

a. Branching enzyme

b Muscle phosphorylase

c. Debranching enzyme

d. Glucose 6 phosphatase