Scribd
Upload
41 views17 pages

Segi College Kuala Lumpur: Group Member Khamini Izaidah

Wuchereria bancrofti is a parasitic roundworm spread by mosquitoes that infects the lymphatic system. It has a complex life cycle involving transmission between mosquito and human hosts. In humans, immature worm stages mature in the lymphatic vessels and can cause swelling and elephantiasis if left untreated. The document discusses the morphology, life cycle, symptoms, diagnosis, and treatment of W. bancrofti infection as well as preventative measures like mosquito control.

Uploaded by

shally918
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
41 views17 pages

Segi College Kuala Lumpur: Group Member Khamini Izaidah

Wuchereria bancrofti is a parasitic roundworm spread by mosquitoes that infects the lymphatic system. It has a complex life cycle involving transmission between mosquito and human hosts. In humans, immature worm stages mature in the lymphatic vessels and can cause swelling and elephantiasis if left untreated. The document discusses the morphology, life cycle, symptoms, diagnosis, and treatment of W. bancrofti infection as well as preventative measures like mosquito control.

Uploaded by

shally918
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
You are on page 1/ 17

SEGI COLLEGE KUALA

LUMPUR

GROUP MEMBER
KHAMINI
IZAIDAH
Wuchereria Bancrofti

INTRODUCTION
Wuchereria bancrofti is a parasitic filarial nematode
(roundworm) spread by a mosquito vector.

Affects the lymphatic circulation.

The three parasites that cause lymphatic filariasis, an
infection of the lymphatic system by filarial worms.

If the infection is left untreated, it can develop into a
chronic disease called elephantiasis.
HABITAT

Found in the adult form of vessels and glands of human
lymphatic vessel .

MORPHOLOGY
W.bancrofti is a sexually dimorphic species.

The adult male worm is long and slender,
between 4 and 5 centimeters in length, a
10 of a centimeter in diameter, and has a
curved tail.



The female is 6 to 10 centimeters long, and
three times larger in diameter than the male.

They are viviparous.

Their vulva is near the level of the middle of
their esophagus.

Microfilariae are sheathed, and approximately
245 to 300 m in length.

Life span : 5-10 years approximately.

VECTOR
Anopheles


Culex
Aedes
LIFE CYCLE
CHARACTERISTIC OF LIFE
CYCLE.
Host: Mosquitoes (intermediate host).

Human (final host).

Location: Lymphatics and lymph nodes.

Infective stage: Inective larvae.

Transmission stage: Microfilariae.

Diagnostic stage: Microfilariae.

PATHOGENESIS
6-12 months must pass before the microfilariae
mature and reproduce

Once a person is infected, microfilariae can be
produced for up to ten years.

There are 3 phases of infections: asymptomatic,
inflammatory (acute), and obstructive.

Asymptomatic Phase

High levels of microfilaria in the blood

No symptoms present

Inflammatory (Acute) Phase

Inflammatory responses happen in response to antigens
from adult worms

Lymphedemaswelling due to blockage of lymph vessels

Orchitisinflammation of the testes

Epididymitisinflammation of the spermatic cord


Obstructive Phase

Lymph varicesenlarged lymph vessels (synonymous with varicose veins)

Lymph scrotum

Chylurialymph in urine (milky and sometimes bloody urine)

Elephantiasisenlargement of limbs and thickening of the skin due to
repeated inflammatory episodes
SIGN AND SYMPTOMS
Filarial fever

Lymphangitis

Lymphadenitis

Leucocytosis & eosinophilia

nausea

vomiting

elephantiasis
LAB DIAGNOSIS
1.Thick blood smear
Juveniles must be present in peripheral blood.

2. Polymerase chain reaction (PCR)
Distinguishes between other similar species.

3. Ultrasonography
Detects vigorous movement of adults known as
filaria dance sign.

4. X-rays
Detects dead, calcified worms.

TREATMENT
1-Antifilarial drugs:-

a- Diethylcarbamazine [DEC]

b- Ivermectin

c- Albendazole

2-General measures: -

Rest, antibiotics, antifungal, physiotherapy &
bandaging.

3-Elephantoid tissues:-

Corrected surgically.
PREVENTION
Mosquito control

Covering water-storage containers and
improving waste- water and solid-waste
treatment systems can help by reducing the
amount of standing water in which mosquitoes
can lay eggs.

Killing eggs (oviciding) and killing or disrupting
larva (larviciding) in bodies of stagnant water
can further reduce mosquito populations.

You might also like

pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy