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Epidemiology and Clinical Characteristic of Patient Acute Gastroenteritis (AGE

This document summarizes a study on acute gastroenteritis (AGE) in hospitalized children in southern Taiwan between 2014-2016. Stool samples were collected from children under 5 years old with AGE symptoms and tested for bacteria, viruses and parasites. The most common pathogen found was Salmonella species, followed by norovirus and rotavirus. The study aimed to identify the major causes of AGE in hospitalized young children in southern Taiwan.

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Gusdek Arya
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38 views12 pages

Epidemiology and Clinical Characteristic of Patient Acute Gastroenteritis (AGE

This document summarizes a study on acute gastroenteritis (AGE) in hospitalized children in southern Taiwan between 2014-2016. Stool samples were collected from children under 5 years old with AGE symptoms and tested for bacteria, viruses and parasites. The most common pathogen found was Salmonella species, followed by norovirus and rotavirus. The study aimed to identify the major causes of AGE in hospitalized young children in southern Taiwan.

Uploaded by

Gusdek Arya
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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Epidemiology and Clinical

Characteristic of patient
Acute Gastroenteritis (AGE
I Nyoman Arep Kusuma Negara
1770121063
SGD 4
Introduction

 Acute gastroenteritis (AGE) represents a major cause of morbidity and mortality


among children. Global Health Observatory data of World Health Organization
reported that diarrheal diseases caused more than 500,000 children deaths in
2015 worldwide, accounted for 9% of deaths in children under 5 years.1
 AGE can be caused by a wide array of pathogens, including bacteria, viruses,
and parasites. Viruses are responsible for approximately 70% of the episodes of
AGE in children, with rotavirus and norovirus being the commonest.3 Rates of
virus infection of AGE are similar in both developed and less developed
countries.4 However, less developed countries have a higher rate of parasites
and bacterial infection, such as Cryptosporidium spp., Shigella spp. and
enterotoxigenic, Escherichia coli.5
 AGE was defined as the symptoms of diarrhea (loose or watery stool more than
3 times per day) and or vomiting within one week
Patient

 Patients aged less than 5 years who were diagnosed as AGE and admitted
to Department of Pediatric of National Cheng Kung University Hospital
between July 2014 and June 2016 were enrolled.
Specimens collection and pathogen
identification
 Stool samples were collected for enteric bacteria culture and virus
detection after admission. For bacteria culture, xylose lysine deoxycholate
agar (XLD agar) and MacConkey agar plate were used for Salmonella and
Shigella species isolation
 The stool samples were also send to Taiwan CDC for a panel of pathogen
identification consisting of two viruses (rotavirus, norovirus), nine bacteria
(Salmonella spp., Shigella spp., Vibrio Cholerae, Vibrio parahemolyticus,
Clostridium difficile, Clostridium perfringens, Campylobacter spp., Listeria
monocytogenes, Bacillus cereus), and five parasites (Cryptosporidium spp.,
Giardia lamblia, Toxoplasma gondii, Entamoeba histolytica, Angiostrongylus
cantonensis) by multiplex molecular testing.
Conclusion

 Salmonella spp. was the most common pathogen of AGE in hospitalized


children in southern Taiwan during 2014 - 2016, followed by norovirus and
rotavirus
Reference

 Chung, N., Wang, S. M., Shen, C. Et al.(2017). Clinical and epidemiological


characteristics in hospitalized young children with acute gastroenteritis in
southern Taiwan: According to major pathogens. Journal of Microbiology,
Immunology and Infection, 50(6), 915–922.
https://doi.org/10.1016/j.jmii.2017.07.015

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