Muscular System: Lecture By: M.K. Sastry
Muscular System: Lecture By: M.K. Sastry
SYSTEM
Lecture by: M.K. Sastry
Outline
• Types and Functions of Muscles
• Smooth
• Cardiac
• Skeletal
• Muscle Innervation
• Whole Muscle Contraction
• Oxygen Deficit
• Athletics and Muscle Contraction
• Slow and Fast Twitch Fibers
• Muscle Disorders
Types and Functions of Muscles
• Smooth muscle is located in the walls of hollow
internal organs and contracts involuntarily.
• Cardiac muscle forms the heart wall and contracts
involuntarily.
• Skeletal muscle runs the entire length of the muscle
and contracts voluntarily.
• Cells are muscle fibers
Functions of Skeletal Muscles
• Body support.
• Bone movement.
• Maintenance of body temperature.
• Assist movement in cardiovascular and lymphatic
vessels.
• Protect internal organs.
• Stabilize joints.
Skeletal Muscles of the Body
• A whole muscle contains bundles of skeletal muscle
fibers, fascicles.
• Muscles are covered with fascia that becomes
tendons.
• Muscles originate on the stationary bone, and insert
on the bone that moves.
Names and Actions of Skeletal Muscles
• Skeletal muscles are named based on
characteristics.
Size
• Gluteus Maximus
Shape
• Deltoid
Direction of muscle fibers
• Rectus abdominus
Number of attachments
• Biceps brachii
Action
• Extensor digitorum
Skeletal Muscle Fiber Contraction
• Overview of Muscular Contraction.
• Nerve impulses originate in the brain, travel down
motor neurons, and stimulate muscle fibers at
neuromuscular junctions.
• When muscle fibers are stimulated to contract,
myofilaments slide past one another, causing
sarcomeres to shorten.
Skeletal Muscle Fiber Contraction
• Sarcolemma (plasma membrane)
• Sarcoplasm
• Myofibrils
• T Tubule
• Sarcoplasmic reticulum
• Contain Ca2+
Light and dark bands (striations)
Sarcomeres
• Thin filaments – actin
• Thick filaments – myosin
Z line, A band, I band, H zone
Sliding filament theory – actin and myosin filaments
moving. Myosin does work. ATP
Muscle Innervation
• Muscle fibers are stimulated to contract by motor
nerve fibers.
• Signaled when nerve impulses bring about release of
neurotransmitter molecules at a neuromuscular
junction.
Muscle Innervation
• Released Calcium gets to troponin
• Troponin causes a shift in tropomyosin
• Myosin head attaches (ATP=ADP + P)
• Stroke (ADP + P released)
• Contraction continues until nerve impulses cease.
Whole Muscle Contraction
• Muscle Twitch - Single muscle contraction.
• Divided into three stages.
• Stimulation.
• Contraction.
• Relaxation.
• If a muscle is given a rapid series of threshold
stimuli, muscle contraction summates in a sustained
contraction, tetanus.
Whole Muscle Contraction
• A motor neuron, together with all of the muscle
fibers that it innervates, is a motor unit.
• As the intensity of nervous stimulation increases,
more motor units are activated. (recruitment)
Energy for Muscle Contraction
• ATP produced previous to strenuous exercise lasts a
few seconds, and then muscles acquire new ATP in
three ways.
• Phosphate breakdown. (anaerobic)
• Fermentation. (anaerobic)
• Cellular respiration. (aerobic)
Oxygen Deficit
• When a muscle uses the anaerobic means of
supplying energy, it incurs an oxygen deficit.
• Repaying an oxygen deficit requires replenishing
creatine phosphate supplies and disposing of lactic
acid.
Athletics and Muscle Contraction
• Muscles that are not used, or are used in only weak
contractions can atrophy.
• Can cause muscle fibers to progressively shorten,
leaving body parts contracted in contorted positions.
• forceful exercise can cause muscle size to increase or
hypertrophy.
Athletics and Muscle Contraction
• Slow-twitch fibers produce most of their energy
aerobically and tire only when their fuel supply is
gone.
• Fast-twitch fibers tend to be anaerobic and seem to
be designed for strength as their motor units
contain many fibers.
• Can develop greater, and more rapid, maximum
tension than slow-twitch fibers.
Homeostasis
• Cardiac muscle contraction accounts for the
heartbeat, delivering blood to the tissues.
• Smooth muscle contraction accounts for peristalsis
and urination.
• Skeletal muscle contraction returns blood to the
heart and moves bones, allowing for body
movement.
Thank You