Nanobiotechnology is the fusion of nanotechnology and biotechnology which allows the manipulation of biological systems at the molecular level using nanoscale tools. It has applications in drug delivery, disease detection, and cardiac therapy. Challenges include monitoring human exposure to nanomaterials, developing methods to test nanomaterial toxicity, and properly assessing risks to health and the environment. While nanobiotechnology shows promise in developing new medical treatments, the long term safety of nanomedicine needs further evaluation.
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Introduction of The Topic: Nano-Biotechnology
Nanobiotechnology is the fusion of nanotechnology and biotechnology which allows the manipulation of biological systems at the molecular level using nanoscale tools. It has applications in drug delivery, disease detection, and cardiac therapy. Challenges include monitoring human exposure to nanomaterials, developing methods to test nanomaterial toxicity, and properly assessing risks to health and the environment. While nanobiotechnology shows promise in developing new medical treatments, the long term safety of nanomedicine needs further evaluation.
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INTRODUCTION OF THE
TOPIC NANO-BIOTECHNOLOGY
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WHAT IS THE NANO- BIOTECHNOLOGY Nanotechnology is a novel scientific approach that involves materials and equipments capable of manipulating physical as well as chemical properties of a substance at molecular levels. On the other hand, biotechnology uses the knowledge and techniques of biology to manipulate molecular, genetic and cellular processes to develop products and services and is used in diverse fields from medicine to agriculture. Nanobiotechnology is considered to be the unique fusion of biotechnology and nanotechnology by which classical micro-technology can be merged to a molecular biological approach in real. Through this methodology, atomic or molecular grade machines can be made by mimicking or incorporating biological systems, or by building tiny tools to study or modulate diverse properties of a biological system on molecular basis. ADVANTAGES OF NANO-BIOTECHNOLOGY 1.Drug targeting can be achieved by taking advantage of the distinct pathophysiological features of diseased tissues
2. Various nanoproducts can be accumulated at higher concentrations
than normal drugs 3. increased vascular permeability coupled with an impaired lymphatic drainage in tumors improve the effect of the nanosystems in the tumors or inflamed tissues through better transmission and retention . 4. Nanosystems les can be effectively used to deliver/transport relevant drugs to the brain overcoming the presence of blood–brain barrier (meninges) APPLICATION OF THE NANO-BIOTECHNOLOGY 1)Diagnostic applications: Current diagnostic methods for most diseases depend on the manifestation of visible symptoms before medical professionals can recognize that the patient suffers from a specific illness.
2)Detection: Many currently used/conventional clinical tests reveal the
presence of a molecule or a disease causing organism by detecting the binding of a specific antibody to the disease-related target.
3) Nanotechnology in cardiac therapy : Nanotechnology is currently
offering promising tools for applications in modern cardiovascular science to explore existing frontiers at the cellular level and treat challenging cardiovascular diseases more effectively. CHALLENGES IN THE NANO- BIOTECHNOLOGY 1) It is fairly understood that exposure of humans and animals to the environment potentially contaminated with nano-materials may need to be monitored for any adverse consequence. The challenge becomes increasingly difficult in more complex matrices like food. 2) The second challenge would be to develop applicable methods to detect and determine the toxicity of engineered nano-materials within next 5 to 15 years. 3) The next challenge would be to develop reverse systems to evaluate precise impact of engineered nano-materials on health and the environment over the entire life span that speaks to the life cycle issue 4) The fifth being more of a grand challenge would be to develop the tools to properly assess risk to human health and to the environment. CONCLUSION
Nanobiotechnology is still in its early stages. The multidisciplinary field of
nanobiotechnology is bringing the science of the almost incomprehensibly small device closer and closer to reality. The effects of these developments will at some point be so vast that they will probably affect virtually all fields of science and technology. Nanobiotechnology offers a wide range of uses in medicine. Innovations such as drug delivery systems are only the beginnings of the start of something new. Many diseases that do not have cures today may be cured by nanotechnology in the future. Although the expectations from nanobiotechnology in medicine are high and the potential benefits are endlessly enlisted, the safety of nanomedicine is not yet fully defined. Use of nanotechnology in medical therapeutics needs adequate evaluation of its risk and safety factors. DESIGNED &WRITTEN BY: ABHISHEK YADAV CLASS:XI-C BATCH-2020-2021 TOPIC-NANO-BIOTECHNOLOGY