Edible Vaccines
Uploaded by
keeEdible Vaccines
Uploaded by
keeEdible Vaccines
By: Akia
INTRODUCTION
Have you ever thought about the idea of using plants
and fruits to create edible vaccines?
• Invented by Charles J. Arntzen
• Made up of antigens grown in genetically modified
plants
• Do not contain genes responsible for pathogenesis
BACKGROUND AND
SIGNIFICANCE
MATERIALS AND
METHODS
RESULTS
ADVANTAGES OF EDIBLE
VACCINES
• Reduces immunization expenses
• Safer (posses antigenic subunits only)
• Needle free
• Enhanced compliance with children
• Multi component ability
OBTACLES TO THE
PRODUCTION
• Antigen selection
• Efficacy in systems
• Choice of plants
• Delivery
• Dosage
• Safety
• Public perception
CLINICAL USE
• Tumor reactive monoclonal antibody
used to treat cancer
• Zona pellucida protein in tobacco
mosaic virus
• Vaccine against Alzheimer’s disease
using beta amyoild gene
• Chloroplasts being used for green
Example of clinical studies
carried out
TABLE 2 from page 474 on article
CHARACTERISTICS OF PLANTS
USED FOR EDIBLE VACCINES
• Plants should produce edible parts that can be
consumed uncooked
• Rich in protein
• Grow widely
• Be capable of being transformed by genetic
engineering
• Should not produce toxic products
DISCUSSION
GROUPS INPUTS/IDEAS TO
PROBLEM STATEMENT
CONCLUSION
REFERENCES
• A banana or a syringe : journey to edible vaccines by
Monica Sharma and Bhumika Sood