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Urinary Schistosomiasis

This document discusses urinary schistosomiasis, which is caused by the parasite Schistosoma haematobium. S. haematobium primarily affects the urinary bladder. Around 80-90 million people are infected with S. haematobium globally. Children and adults in endemic areas are most at risk. Initial symptoms include hematuria and dysuria. Over time, this can progress to complications like hydronephrosis, bladder cancer, and fibrosis of the bladder and ureters if left untreated. Diagnosis involves finding eggs from the parasite in urine samples or bladder biopsies.

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Ernesto De Sago
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0% found this document useful (0 votes)
72 views12 pages

Urinary Schistosomiasis

This document discusses urinary schistosomiasis, which is caused by the parasite Schistosoma haematobium. S. haematobium primarily affects the urinary bladder. Around 80-90 million people are infected with S. haematobium globally. Children and adults in endemic areas are most at risk. Initial symptoms include hematuria and dysuria. Over time, this can progress to complications like hydronephrosis, bladder cancer, and fibrosis of the bladder and ureters if left untreated. Diagnosis involves finding eggs from the parasite in urine samples or bladder biopsies.

Uploaded by

Ernesto De Sago
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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GROUP 09

URINARY SCHISTOSOMIASIS
Introduction
Schistosomiasis is a group of diseases caused by
a TREMADOTES of genus Schistosoma, also by
their common name known as blood flukes.
Three main species infect human;
• Schistosoma mansoni
• Schistosoma japonicum
• Schistosoma haematobium(affecting urinary
bladder)
Epidemiology
• Of the 200 million people affected with
schistosomiasis, 80 to 90 million are infected
with S.Haematobium.
• As many as 10 to 40 million have obstructive
uropathy or other complications secondary to
this parasitic disease.
Pathogenesis of Schistosomiasis
• The disease mainly affects children and adults in
endemic areas
• The initial reaction may be dermatitis from cercarial
penetration
• Acute phase of heavy first infection presents with
typhoid fever- like symptoms, fever, cough,
myalgia(pain), malaise and hepatosplenomegaly
• Cirrhosis of the liver, bloody diarrhoea, hypertension,
and toxic reactions may occur because of granulomas
around eggs in liver, urinary bladder, central nervous
system and other tissues
• Eosinophilia is present.
CONT…..
• Most chronic cases are asymptomatic in
endemic areas. Schistosomes feed on red
blood cells; brown haematin pigment is
present in phagocytic cells
• Nephrotic syndrome may occur in
Schistosoma haematobium
• Sch. Haematobium has a clinical correlation
with bladder cancer
Blood cancer
• This is the final pathologic sequelae of
schistosomiasis.
• High frequency of squamous cell
carcinomas(60% to 90%), with 5% to 15%
adenocarcinomas.
Clinical manifestations
• Hematuria and terminal dysuria is the first
sign of the established S.Haematobium
infection, often appearing 10 to 12 weeks
after infection.
• Involvement of these genital structures often
present with scrotal pain or testicular mass
CONT….
• Overtime, a late, chronic, active stage
develops “schistosomal contracted bladder”
consistent with pelvic pain with associated
urinary urgency, frequency and incontinence.
• Patients finally enter a Chronic inactive phase
in which viable eggs are no longer detected in
urine or tissue.
CONT….
• Silent obstructive uropathy may develop
throughout this phase as fibrosis replaces
polypoid lesions and the bladder and ureter s
undergo irreversible damage.
Diagnosis
• The presence of eggs in urinary sediment is
diagnostic.
• If the eggs are not found in urine, a bladder
biopsy should be attempted.
Reference
• http://www.ncbi.nlm.nih.gov/pmc/articles/P
MC7826813/
• http://www.slideshare.net/dralameddine/urin
ary-schistosomiasis
Group Participants
S/N NAME REG. NUMBER REMARKS

01. ERNEST PETER SAGO DECCA06/S22/02/0004 FULL PARTICIPATED

02. JOSEPH LUPUMKO MAGEHEMA DECCA/18/02/826 FULL PARTICIPATED

03. KHADIJA ABDALLAH DECCA/S20/02/0057 FULL PARTICIPATED

04. DEOGRATIUS MLOYAAA DECCA/S20/02/0056 FULL PARTICIPATED

05. IDDY O LIGUO DECCA/S20/02/0030 FULL PARTICIPATED

THANK YOU

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