CCN Minerals
CCN Minerals
Regulate
Calcium
Homeostasis
(Balance)
High Blood Calcium
Trabecular Bone:
Inside of bone; more sensitive to
changes in dietary calcium
Calcium Functions: Many Important Roles:
Muscle Contraction
Nerve Transmission – release of Neurotransmitter!
Regulating Hormones and Enzymes
Blood Vessel Dilation/Constriction: Blood Pressure
Blood Clotting
Calcium May:
Prevent Colon Cancer – by protecting lining of
tract from caustic and abrasive substances.
Reduce the risk of kidney stones – Ca2+ binds to
oxalates in foods.
Reduce the risk of obesity – by normalizing
interactions between hormones.
Inadequate Ca2+ shifts hormonal response of PTH and
calcitriol which may stimulate fat production and storage.
Daily Needs for Ca2+
AI for Adults: 1,000 to 1,100 mg/day
UL: 2,500 mg/day
Americans fall short, consuming < 800 mg/day.
Ca2+ Toxicity
Hypercalcemia: Too much Ca2+ in blood
Symptoms:
• Constipation
• Bone pain
• Muscle weakness
• Mental confusion
• Impairs absorption of Fe, Zn, Mg and P.
Ca2+ Deficiency
Hypocalcemia: Blood Ca2+ levels below normal
Bones less dense, weakened and brittle.
risk of Osteoporosis and Bone Fractures
P Deficiency is rare.
Hypophosphatemia
Muscle weakness, bone pain, rickets, confusion,
and death in extreme cases!
RDA Adult: 700 mg/day
UL: 4,000 mg/day
P Deficiency is rare.
Hypophosphatemia
Muscle weakness, bone pain, rickets, confusion,
and death in extreme cases!
Potassium (K+)
• Major Cation in intracellular fluid (ICF)
• Absorbed in Small Intestine and Colon
• Kidneys regulate balance excreting excess.
• Muscle Contraction and Nerve Impulse.
• Rhythmic Heart Beats.
• Regulate Blood Pressure when excreted.
• Acts as a Buffer in Blood.
• Preserves Ca2+ and PO43- in bones.
Minor amounts are lost in sweat.
Daily Needs
Adults: 4,700mg/day. Most Americans fall short.
F ~2,200 and
May Hypertension. M~3,300mg/day.
Absorption
– Is absorbed throughout the GI tract
– About 80% SO42- consumed is Absorbed.
– Kidneys excrete excess.
Metabolic Functions of Sulfate
Na also Located:
• Within Hydroxyapatite crystals in bone;
• In Nervous Tissue;
• In Muscular Tissue. Table salt – accounts for 90% of our Na - part
of our problem? Please, use Sea Salt!
40% wt table salt = Na; 60% wt table salt = Cl
Absorption, Transport, and Excretion of Na
• 95-100% absorbed in Small Intestine!
• About 5% Excreted in Feces.
• Blood levels Maintained by Kidneys.
Aldosterone causes
kidney to retain sodium!
Na plays a role in nerve impulse transmission
and participates in
muscle contraction
• Deficiency - Rare
From prolonged diarrhea or vomiting.
Diuretics can increase urinary losses.
Absorption
A high-fiber, whole-grain, high phytates, lowers
absorption.
Intestinal absorption and kidney excretion
adjusts based on diet and need.
Daily Needs for Mg
Adults: 300 to 400 mg/day
Americans fall short of consuming adequate Mg.
Mg2+ Toxicity - Consuming excess supplements
can cause intestinal problems.
Diarrhea, cramps, nausea
Symptoms:
Muscle weakness, seizures, fatigue, depression, and
irregular heart beats.
Bone Mass