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Centrioles

A brief presentation about the intricacies of the centrioles: A biotech presentation

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Sean Michael Calanayan
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55 views16 pages

Centrioles

A brief presentation about the intricacies of the centrioles: A biotech presentation

Uploaded by

Sean Michael Calanayan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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Centrioles


By Abigail Hannah O. Arias
& Jhasmine M. Aquino
Centrioles

 It is a small structure made of
microtubules which exists as part
of the centrosome, which helps
organize microtubules in the body.
 It is also the main unit that creates
and anchors microtubules in the
cell.

 Each cell may have hundreds or thousands of
microtubules that extend to various parts of
the cell.
 Microtubules extend from the each centriole,
and use the centriole as an anchor for the
base of each microtubule.
 Centrioles or centrosomes are present only in
animal cells; absent in plant cells (except
fungal cells) & prokaryotes. In the interphase
of cell, a pair of centrioles are found located
near nucleus.
Each centriole is a non-membranous
hollow cylindrical structure measuring
about 0.15 µ in diameter.
A centriole is barrel shaped polarized structure
made up of microtubules(tubulin protein) and is
an important part of centrosomes. They are
present in most animal cells, fungi and algae but
not in plants.
Functions

 There are two main functions of
centrioles that we will focus on. The
main function of the centriole is to help
with cell division in animal cells. The
centrioles help in the formation of the
spindle fibers that separate the
chromosomes during cell division
(mitosis).
 Centrioles also produce the basal
bodies from which cilia and flagella
Structure

 A centriole is made of nine sets of
microtubules, each in groups of three
known as triplet microtubules. Triplet
microtubules are very strong because
they are composed of three concentric
rings of microtubules that form
together. Triplet microtubules are seen
in other strong microtubules structures,
such as the basal bodies of cilia and
flagella.
Structure

 . Each triplet is bonded together by special
proteins that give a centriole its shape.
Surrounding the triplet microtubules is a
amorphous material called pericentriolar
material, which contains many of the
molecules necessary for the construction of
microtubules. Each microtubule in a triplet
is made up of small units of tubulin, a small
monomer that can join together to create
long, hollow tubes that resemble straws.
Terms

 Microtubule-organizing Center – A centrosome
during mitosis, when a large microtubule
network is created.
 Centrosome – The center for microtubule
activity in a cell, which consists of two
centrioles.
 Centromere – The portion of a chromosome
which can be attached to by microtubule
associating proteins.
 Kinetochore – The specific region within a
centromere that has the ability to form bonds
with other molecules.
Disease

 Defects in centrioles are associated
with microcephaly and mental
retardation. The reduction in brain
size is related to the loss of
neuronal progenitor cells. Defects in
centrioles may also be associated
with Sjögren syndrome, an
autoimmune disease, because of
defects in formation of the
Quiz Time

¼ sheet of paper; write 1-10
Go Bermuda triangle
Identification

1. the main unit that creates and anchors
microtubules in the cell.
2. Each centriole is a non-membranous hollow
cylindrical structure measuring about ______ µ
in diameter.
3. What do you call the center for microtubule
activity in a cell, which consists of two
centrioles.
4. Defects in centrioles are associated with
__________ and mental retardation.
True or False

5. They are present in most animal cells, fungi
and algae but not in plants.
6. The main function of the centriole is to help
with cell division in animal cells.
7. The cilia is a small structure made of
microtubules which exists as part of the
centrosome, which helps organize
microtubules in the body.
8. In the interphase of cell, a pair of centrioles
are found located away from the nucleus.
Enumeration

9-10: what are the two things develop when
Basal Bodies are produce?
Answers

Hays sa wakas tapos na!
Answers

1.Centrioles 7.False
2.0.15 8.False
3.Centrosome 9.cilia
4.Microcephaly 10.flagella
5.True
6.True

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