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NMT 06101
CARE OF A WOMAN WITH
ABNORMAL PREGNANCY, LABOUR AND PUERPERIUM CARE OF A WOMAN WITH HYPEREMESIS GRAVIDARUM AND DISORDERS OF AMNIOTIC FLUID (POLYHYDRAMNIOS AND OLIGOHYDRAMNIOS) BY B. MWAIPASI BSc Mw – UDOM mwaipasi64@gmail.com Learning Tasks At the end of this session, a learner is expected to be able to: 1. Define hyperemesis gravidarum 2. Explain causes and diagnosis of hyperemesis gravidarum 3. Outline signs and symptoms of hyperemesis gravidarum 4. Describe the management of a pregnant woman with hyperemesis gravidarum Definition of Hyperemesis Gravidarum Hyperemesis gravidarum Is an excessive nausea and vomiting that start between 4-10 weeks gestation, and resolve before 20 weeks Causes and Diagnosis of Hyperemesis Gravidarum The causes of hyperemesis is uncertain, with multi-factorial causes such as: Hormonal /Endocrine • High human chorionic ganadotrophin (hCG) stimulates the chemoreceptor trigger zone in the brain stem including the vomiting center. • Allergy to the corpus luteum or the released hormones. Cont…….. Nervous and psychological due psychological rejection of an unwanted pregnancy Deficiency of: • Adrenocortical hormone and /or, • Vitamin B6 and B1 Cont…….. Hyperemesis occur more often where mothers have a multiple pregnancy, or a hydatidiform Simultaneously occurrence of hyperthyroidism and hyperemesis suggest transient thyroid dysfunction as a possible cause Sign and Symptoms of Hyperemesis Gravidarum The patient cannot retain anything in her stomach. • Vomiting occurs through the day and night even without eating. Thirst, constipation and oliguria. In severe cases, vomitus is bile and/ or blood stained. Finally, there are manifestations of Werniche’s encephalopathy as drowsiness, Cont…….. Manifestations of starvation and dehydration: • Loss of weight. • Sunken eyes. • Dry tongue and inelastic skin. • Pulse: rapid and weak. • Blood pressure: low. • Temperature: slight rise Care of a Pregnant Woman with Hyperemesis Gravidarum The woman should be hospitalized for observation and fluid therapy Nil per oral (nothing by mouth) for24–48 hrs. Calm reassurance and sensitive information-giving should be accompanied by competent attention to physical needs. On arrival in hospital blood will be taken to determine the plasma electrolytes. Cont…….. The potassium and sodium levels will be corrected by intravenous infusion( Ringers lactate) The infusion will continue until hydration and electrolytes return to normal. Vitamins B12 and C, folic acid and iron will be required to correct anaemia. Cont…….. The pregnant woman should be given Promethazine (IM) 12.5 mg 12hourly a day if vomiting persists and a sedative may be given to produce rest. Advice the woman to take small quantity of meals frequently. Monitor vital signs at least 4 hourly Test urine twice for specific gravity, acetone, sugar and protein Cont…….. Monitor and record the intake and output of fluids including vomitus. 24- 48 hrs Once vomiting has ceased for a period of 24 hrs, oral fluids may be commenced and if these are tolerated a light diet may follow. Normal food is gradually introduced and intravenous therapy discontinued Cont…….. Note Very occasional the disorder fails to improve with the treatment outlined above and The mother will subside into coma and be in danger of dying. Pharmacological Treatment • Compound sodium lactate with 5% dextrose and 0.9%sodium chloride according to daily needs and severity. • AND • Vitamin B1 (IV)100mg 24hourly mix in intravenous rehydration solution AND • Metoclopramide (IM) 5–10 mg 8hourly till vomiting stops. OR • Promethazine (IM) 12.5 mg 12hourly a day s o f d er n d o r i s ni o s a t h D w i r am a n h y d o m o l y a W d (P e o f l u i ) r Ca iotic amni F o s m n d r A o h y Ol i g Learning Tasks At the end of this session a learner is expected to be able to: 1. Define the terms polyhydramnios and oligohydramnios 2. State causes and predisposing factors of polyhydramnios and oligohydramnios 3. Describe the management of a pregnant woman with polyhydramnios and oligohydramnios 4. State the complications associated with polyhydramnios and oligohydramnios Definition of Polyhydramnios and Oligohydramnios Polyhydramnios (hydramnios) is an excessive amount of amniotic fluid. • Is defined as the amount of amniotic fluid which exceeds 1500 ml. • It may not be clinically apparent until it reaches 3000 ml. Oligohydramnios is an abnormally small amount of amniotic fluid. Causes and Predisposing Factors of Polyhydramnios and Oligohydramnios Causes and predisposing factors of polyhydramnios Most polyhydramios is of unknown etiology. The following conditions are more likely to result into polyhydramnios: • Multiple pregnancy (especially with monozygotic twins) • Diabetes Cont…….. • Erythroblastosis • Fetal malformations (especially of the gastrointestinal tract—e.g., tracheoesophageal fistula—or central nervous system—e.g., anencephaly, meningomyelocele) Causes and predisposing factors of oligohydramnios • The condition is frequently caused by uteroplacental insufficiency, which there by means that a decreased fluid volume may be associated with a marked increase in perinatal mortality. • The following conditions are more likely to result into oligohydramnios: Cont…….. Congenital anomalies (e.g., renal agenesis, Potter’s syndrome) Viral diseases Intrauterine growth restriction (IUGR) Uteroplacental insufficiency Early rupture of the fetal membranes (24 to 26 weeks) Cont…….. Response to indocin as a tocolytic Fetal hypoxia Meconium-stained fluid and meconium aspiration Postmaturity syndrome Care of a Woman with Polyhydramnios Assessing the woman thorough On history taking the woman will complain of Breathlessness and discomfort Abdominal pain in severe cases Exacerbation of associated symptoms of pregnancy such as; indigestion, heartburns and constipation. Lower swelling and varicosities of vulva and Cont…….. Abdominal examination Inspection • The uterus is larger than expected for the period of gestation and is globular in shape • Abdominal skin appears stretched and shiny with marked stripe gravidarum and obvious superficial blood vessels Cont…….. Palpation • Uterus feels tense and is difficult to feel the Fetal parts • Fetal ballottement between the two hands • Fluid thrill may be elicited by placing a hand on one side of the abdomen and taping the other side with fingers Cont…….. • Measurement of abdominal girth • In cases of acute hydramnios it is done in order to observe the rate of increase Auscultation • May be difficult if the quantity of fluid allows the foetus to move away from the stethoscope Ultrasound • Is used to confirm the diagnosis of Management of polyhydramnios • The aim of management is to relieve maternal symptoms and optimize the length of gestation, prolonging it if safe. • When the cause is already determined The mother will usually be admitted to a consultant obstetric unit. Cont…….. Subsequent care will depend on the mother’s condition, the cause of the polyhydramnios and the stage of pregnancy. The mother should rest in bed. An upright position will help to relieve any dyspnea and she may be given antacids to relieve heartburn and nausea. Acute polyhydramnios is managed by Cont…….. The mother may need to have labor induced in late pregnancy if the symptoms become worse. Labor is usually normal but the midwife should be prepared for the possibility of postpartum hemorrhage. Cont…….. The baby should be carefully examined for abnormalities and a wide orogastric tube must be passed for about 10-12cm. in order to confirm the patency of the oesophagus Care of a Woman with Oligohydramnios Assessment of the mother History taking The woman who had a previous normal pregnancy may have noticed a reduction in fetal movements. History of vagina leakage Cont…….. Abdominal Examination • Inspection The uterus appears smaller than expected for the period of gestation. • Palpation The uterus is small and compact and fetal parts are easily felt Breech presentation is possible. • Auscultation is normal Diagnosis Ultrasonic scan will exclude • Intra-uterine growth restriction. • Renal abnormality. • Coexisting fetal or placental conditions or complications. Screen for diabetes and Rh iso- oimmunization Care of woman with oligohydramnios The woman should be admitted for investigations which will include placental function tests. If there is no fetal abnormality the pregnancy will be allowed to continue Labor may begin early or may be induced because of the possibility of placental insufficiency. Epidural analgesia may be indicated Cont…….. Impairment of placental circulation may result in fetal hypoxia. Constriction rings are a possibility due to the small amount of amniotic fluid. In rare cases the membranes may adhere to the fetus. Reassure the woman and the partner on the condition Complications of Polyhydramnios and Oligohydramnios Polyhydramnios complications Preterm labor (due to over distention of the uterus) Maternal dyspnea and shortness of breath Fetal malpresentations Abruptio placenta Cord prolapse Cont…….. Uterine dysfunction during labor (due to over distention of the uterus) Immediate postpartum hemorrhage as a result of uterine atony from over distention Cont…….. Oligohydramnios complications Lack of amniotic fluid reduces the intra- uterine space and causes compression deformities. The baby has a squashed-looking face, flattening of the nose, micrognathia and talipes. The skin is dry and leathery in appearance Key points • Polyhydramnios (hydramnios) is an excessive amount of amniotic fluid. • The woman needs emotional support especially if congenital anomalies are present. • Women with severe polyhydramnios have a number of mechanical difficulties and discomforts for which the midwife can provide relief measures. • Oligohydramnios is an abnormally small amount of amniotic fluid. • Oligohydramnios is a significant finding suggestive of post-maturity syndrome in a postdate pregnancy. Any question Session Evaluation 1. What are the differences between polyhydramnios and oligohydramnios? 2. What are the complications of polyhydramnios? 3. What are the complications of Oligohydramnios? THE END