Placenta 1pptx
Placenta 1pptx
Nadia Naseem
Lecturer
Subject: Obstetrics
Faculty of Eastern Medicine
Hamdard University
Introduction
▪ The word placenta comes from the Latin word means “cake”. The placenta is a flattened circular
organ in the uterus of pregnant woman that nourishes and maintain the fetus through the
umbilical cord.
▪ It has two surfaces maternal surface formed by decidua and fetal surface is formed by
trophoblast.
▪ Maternal blood flow to the placenta is approx. 500 to 600ml / min. Intervillous space contain
150ml blood and in villi system 350 ml blood so total volume is 500ml blood this is placental
volume.
▪ It is about 20 cm in diameter.
▪ It is thick from the center ( Thickness is 2.5cm to 3cm ) and thin from peripheral ( 1 cm to 1.5
cm)
▪ It provide nutrition.
▪ Respiration
▪ Secrete certain hormones ( progesterone , small quantity of estrogen,
human chorionic gonadotropin , human chorionic lactogen /human
placental lactogen/human chorionic somatomammotropin).
▪ It acts as a barrier, but certain substances can cross placenta like viruses
(rubella, HIV etc.) nicotine , heroine if crosses might cause defects in the
fetus .Such substances are called teratogens . one such teratogen is
mercury which cross placenta and cause a disease called Minamata.
Trophoblast
cytotrophobl syncytiotropho
ast blast
Syncyhiotrophoblast is a thick outer layer of multinucleated
cells. It prevent the deeper penetration of the blastocyst into the
myometrium. And late on this layer forms a layer of fibrin (fibrinoid
material) called as Nitabuch's layer. If this layer is absent than it will
give rise to a condition called as placenta accreta
3. Yolk sac
Nadia Naseem
Lecturer
Subject: Obstetrics
Faculty of Eastern Medicine
Hamdard University
Abnormalities of placenta
Placenta succenturiate
Circumvallate
Maternal blood
Fetal blood vessels
vessels have
have fetal blood
maternal blood
HbF HbA
Resistance to Sensitive to acid and
acid/alkali alkali
If blood hemolysis
If no hemolysis this
and color change to
mean HbF
brown this mean HbA