Chapter - 2
Chapter - 2
Neoplasms
(C00-D49)
Chapter 2 of the ICD-10-CM contains the codes for most benign and all
malignant neoplasms. Certain benign neoplasms, such as prostatic
adenomas, may be found in the specific body system chapters.
To properly code a neoplasm, it is necessary to determine from the
record if the neoplasm is benign, in-situ, malignant, or of uncertain
histologic behavior. If malignant, any secondary (metastatic) sites should
also be determined.
Treatment directed at the malignancy
If the treatment is directed at the malignancy, designate the malignancy
as the principal diagnosis.
The only exception to this guideline is if a patient admission/encounter is
solely for the administration of chemotherapy, immunotherapy or
external beam radiation therapy, assign the appropriate Z51.-- code as
the first-listed or principal diagnosis, and the diagnosis or problem for
which the service is being performed as a secondary diagnosis.
Treatment of secondary site
When a patient is admitted because of a primary neoplasm with
metastasis and treatment is directed toward the secondary site only, the
secondary neoplasm is designated as the principal diagnosis even though
the primary malignancy is still present.
Coding and sequencing of complications
Anemia associated with malignancy
When admission/encounter is for management of an anemia associated
with the malignancy, and the treatment is only for anemia, the
appropriate code for the malignancy is sequenced as the principal or first-
listed diagnosis followed by the appropriate code for the anemia (such as
code D63.0, Anemia in neoplastic disease).
Anemia associated with chemotherapy, immunotherapy and
radiation therapy
When the admission/encounter is for management of an anemia
associated with an adverse effect of the administration of
chemotherapy or immunotherapy and the only treatment is for
the anemia, the anemia code is sequenced first followed by the
appropriate codes for the neoplasm and the adverse effect
(T45.1X5-, Adverse effect of antineoplastic and
immunosuppressive drugs).
When the admission/encounter is for management of an anemia
associated with an adverse effect of radiotherapy, the anemia code
should be sequenced first, followed by the appropriate neoplasm code
and code Y84.2, Radiological procedure and radiotherapy as the cause of
abnormal reaction of the patient, or of later complication, without
mention of misadventure at the time of the procedure.
Management of dehydration due to the malignancy
When the admission/encounter is for management of dehydration due to
the malignancy and only the dehydration is being treated (intravenous
rehydration), the dehydration is sequenced first, followed by the code(s)
for the malignancy.
Treatment of a complication resulting from a surgical procedure
When the admission/encounter is for treatment of a complication
resulting from a surgical procedure, designate the complication as the
principal or first-listed diagnosis if treatment is directed at resolving the
complication.
Primary malignancy previously excised
When a primary malignancy has been previously excised or eradicated
from its site and there is no further treatment directed to that site and
there is no evidence of any existing primary malignancy at that site, a
code from category Z85, Personal history of malignant neoplasm, should
be used to indicate the former site of the malignancy.
Any mention of extension, invasion, or metastasis to another site
is coded as a secondary malignant neoplasm to that site. The
secondary site may be the principal or first-listed diagnosis with
the Z85 code used as a secondary code.