About: BK channel

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

BK channels (big potassium), are large conductance calcium-activated potassium channels, also known as Maxi-K, slo1, or Kca1.1. BK channels are voltage-gated potassium channels that conduct large amounts of potassium ions (K+) across the cell membrane, hence their name, big potassium. These channels can be activated (opened) by either electrical means, or by increasing Ca2+ concentrations in the cell. BK channels help regulate physiological processes, such as circadian behavioral rhythms and neuronal excitability. BK channels are also involved in many processes in the body, as it is a ubiquitous channel. They have a tetrameric structure that is composed of a transmembrane domain, voltage sensing domain, potassium channel domain, and a cytoplasmic C-terminal domain, with many X-ray structur

thumbnail
Property Value
dbo:abstract
  • BK channels (big potassium), are large conductance calcium-activated potassium channels, also known as Maxi-K, slo1, or Kca1.1. BK channels are voltage-gated potassium channels that conduct large amounts of potassium ions (K+) across the cell membrane, hence their name, big potassium. These channels can be activated (opened) by either electrical means, or by increasing Ca2+ concentrations in the cell. BK channels help regulate physiological processes, such as circadian behavioral rhythms and neuronal excitability. BK channels are also involved in many processes in the body, as it is a ubiquitous channel. They have a tetrameric structure that is composed of a transmembrane domain, voltage sensing domain, potassium channel domain, and a cytoplasmic C-terminal domain, with many X-ray structures for reference. Their function is to repolarize the membrane potential by allowing for potassium to flow outward, in response to a depolarization or increase in calcium levels. (en)
dbo:arm
  • q
dbo:band
  • 22
  • 26.3
  • 15
  • 34
  • 11.1
  • 26.32
dbo:chromosome
  • 10
  • 12
  • 5
  • 3
  • 22
dbo:entrezgene
  • 3779
  • 10242
  • 27093
  • 27094
  • 27345
  • 3778
dbo:hgncid
  • 6287
  • 6286
  • 6284
  • 6285
  • 6288
  • 6289
dbo:locusSupplementaryData
  • -q27
dbo:omim
  • 600150 (xsd:integer)
  • 603951 (xsd:integer)
  • 605214 (xsd:integer)
  • 605222 (xsd:integer)
  • 605223 (xsd:integer)
dbo:refseq
  • NG_002679
  • NM_002247
  • NM_004137
  • NM_014505
  • NM_171828
  • NM_181361
dbo:symbol
  • BK_channel_a
  • KCNMA1
  • KCNMB1
  • KCNMB2
  • KCNMB2, KCNMBL
  • KCNMB2L, KCNMBLP
  • KCNMB3
  • KCNMB3L
  • KCNMB4
  • SLO
dbo:thumbnail
dbo:uniprot
  • Q12791
  • Q16558
  • Q86W47
  • Q9NPA1
  • Q9Y691
dbo:wikiPageExternalLink
dbo:wikiPageID
  • 463847 (xsd:integer)
dbo:wikiPageLength
  • 32145 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1109076307 (xsd:integer)
dbo:wikiPageWikiLink
dbp:altsymbols
  • SLO (en)
  • KCNMB2, KCNMBL (en)
  • KCNMB2L, KCNMBLP (en)
dbp:arm
  • q (en)
dbp:band
  • 11.100000 (xsd:double)
  • 15 (xsd:integer)
  • 22 (xsd:integer)
  • 26.300000 (xsd:double)
  • 26.320000 (xsd:double)
  • 34 (xsd:integer)
dbp:caption
  • The domain structure of BK channels (en)
dbp:chromosome
  • 3 (xsd:integer)
  • 5 (xsd:integer)
  • 10 (xsd:integer)
  • 12 (xsd:integer)
  • 22 (xsd:integer)
dbp:entrezgene
  • 3778 (xsd:integer)
  • 3779 (xsd:integer)
  • 10242 (xsd:integer)
  • 27093 (xsd:integer)
  • 27094 (xsd:integer)
  • 27345 (xsd:integer)
dbp:hgncid
  • 6284 (xsd:integer)
  • 6285 (xsd:integer)
  • 6286 (xsd:integer)
  • 6287 (xsd:integer)
  • 6288 (xsd:integer)
  • 6289 (xsd:integer)
dbp:interpro
  • IPR003929 (en)
dbp:locussupplementarydata
  • -q27 (en)
dbp:name
dbp:omim
  • 600150 (xsd:integer)
  • 603951 (xsd:integer)
  • 605214 (xsd:integer)
  • 605222 (xsd:integer)
  • 605223 (xsd:integer)
dbp:pfam
  • PF03493 (en)
dbp:refseq
  • NG_002679 (en)
  • NM_002247 (en)
  • NM_004137 (en)
  • NM_014505 (en)
  • NM_171828 (en)
  • NM_181361 (en)
dbp:symbol
dbp:uniprot
  • Q12791 (en)
  • Q16558 (en)
  • Q86W47 (en)
  • Q9NPA1 (en)
  • Q9Y691 (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • BK channels (big potassium), are large conductance calcium-activated potassium channels, also known as Maxi-K, slo1, or Kca1.1. BK channels are voltage-gated potassium channels that conduct large amounts of potassium ions (K+) across the cell membrane, hence their name, big potassium. These channels can be activated (opened) by either electrical means, or by increasing Ca2+ concentrations in the cell. BK channels help regulate physiological processes, such as circadian behavioral rhythms and neuronal excitability. BK channels are also involved in many processes in the body, as it is a ubiquitous channel. They have a tetrameric structure that is composed of a transmembrane domain, voltage sensing domain, potassium channel domain, and a cytoplasmic C-terminal domain, with many X-ray structur (en)
rdfs:label
  • BK channel (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
foaf:name
  • KCNMB3L (en)
  • KCNMA1 (en)
  • KCNMB1 (en)
  • KCNMB2 (en)
  • KCNMB3 (en)
  • KCNMB4 (en)
is dbo:wikiPageDisambiguates of
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License
pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy