Lucila Gamero de Medina (12 June 1873 – 23 January 1964) was a Honduran romantic novelist. She was the first woman in Honduras to produce literary work and in Central America to publish novels. Critic and writer Luis Marín Otero called her "the grand dame of Honduran letters". She was trained as a physician and pharmacist and though prevented from studying at the university was awarded a diploma of Medicine and Surgery from the dean of the Faculty of Medicine. She headed a hospital and served as a health inspector in her native department. In addition to her medical and literary efforts, Gamero was an active feminist and suffragette, attending conferences and participating in the founding of the Comité Femenino Hondureño.