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The mir-BHRF1-2 microRNA precursor found in human herpesvirus 4 (Epstein–Barr virus), cercopithicine herpesvirus 15 and herpesvirus papio. In Epstein-Barr virus, mir-BHRF1-2 is found in the 3' UTR of the (Bam HI fragment H rightward open reading frame 1) gene, which is known to encode a distant Bcl-2 homolog. The mature sequence is excised from the 3' arm of the hairpin. Two other miRNA precursors were found in this reading frame, namely Mir-BHRF1-1 and Mir-BHRF1-3.

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  • The mir-BHRF1-2 microRNA precursor found in human herpesvirus 4 (Epstein–Barr virus), cercopithicine herpesvirus 15 and herpesvirus papio. In Epstein-Barr virus, mir-BHRF1-2 is found in the 3' UTR of the (Bam HI fragment H rightward open reading frame 1) gene, which is known to encode a distant Bcl-2 homolog. The mature sequence is excised from the 3' arm of the hairpin. Two other miRNA precursors were found in this reading frame, namely Mir-BHRF1-1 and Mir-BHRF1-3. BHRF-1-2 miRNA is thought to operate as part of a 'miRNA cluster' with two other microRNAs also found in the Epstein-Barr virus genome. BHRF-1-2 has been shown to be expressed in latency-III infected lymphoblasts. (en)
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dbp:caption
  • Predicted secondary structure and sequence conservation of mir-BHRF1-2 (en)
dbp:id
  • RF00366 (en)
dbp:mirbase
  • MI0001065 (en)
dbp:mirbaseFamily
  • MIPF0000332 (en)
dbp:name
  • mir-BHRF1-2 microRNA precursor family (en)
dbp:rfam
  • RF00366 (en)
dbp:rnaType
dbp:symbol
  • mir-BHRF1-2 (en)
dbp:taxDomain
  • Viruses (en)
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  • The mir-BHRF1-2 microRNA precursor found in human herpesvirus 4 (Epstein–Barr virus), cercopithicine herpesvirus 15 and herpesvirus papio. In Epstein-Barr virus, mir-BHRF1-2 is found in the 3' UTR of the (Bam HI fragment H rightward open reading frame 1) gene, which is known to encode a distant Bcl-2 homolog. The mature sequence is excised from the 3' arm of the hairpin. Two other miRNA precursors were found in this reading frame, namely Mir-BHRF1-1 and Mir-BHRF1-3. (en)
rdfs:label
  • Mir-BHRF1-2 microRNA precursor family (en)
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