dbo:abstract
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- Novimmune is a privately held Swiss pharmaceutical development company focusing on monoclonal antibody therapies for treatment of immune-related diseases. The company was founded in 1998. Novimmune has six publicly disclosed drug in their pipeline:
* , an anti-TLR4 antibody being developed in partnership with Genentech. A phase I clinical trial was completed in 2014 and phase II trials are expected to begin in early 2017.
* , an anti-CD3ε antibody being developed in partnership with . Phase II trials in patients with Crohn's disease and transplant rejection finished in 2008 and 2009, respectively.
* NI-0501, an anti-IFNγ antibody, is in development for hemophagocytic lymphohistiocytosis. A phase II/III trial began in 2013 and is ongoing. The FDA awarded breakthrough status to the drug in 2016.
* , an anti-IL17 drug being developed in partnership with Genentech for inflammatory and auto-immune diseases.
* , an anti-CD47, anti-CD19 bispecific antibody in development for treatment of B-cell hematological cancers.
* , an anti-CD47, anti-mesothelin bispecific antibody in the preclinical phase of development for treatment of solid tumors. No drugs have been approved yet. (en)
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