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RPP14

S Wikipedije, slobodne enciklopedije
RPP14
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

3IR3

Identifikatori
AliasiRPP14
Vanjski ID-jeviOMIM: 606112 MGI: 1914303 HomoloGene: 5113 GeneCards: RPP14
Lokacija gena (čovjek)
Hromosom 3 (čovjek)
Hrom.Hromosom 3 (čovjek)[1]
Hromosom 3 (čovjek)
Genomska lokacija za RPP14
Genomska lokacija za RPP14
Bend3p14.3Početak58,306,245 bp[1]
Kraj58,324,695 bp[1]
Lokacija gena (miš)
Hromosom 14 (miš)
Hrom.Hromosom 14 (miš)[2]
Hromosom 14 (miš)
Genomska lokacija za RPP14
Genomska lokacija za RPP14
Bend14|14 A1Početak14,377,939 bp[2]
Kraj14,389,406 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija ribonuclease activity
hydrolase activity
vezivanje sa RNK
ribonuclease P activity
lyase activity
3-hydroxyacyl-CoA dehydratase activity
Ćelijska komponenta jedro
nukleoplazma
multimeric ribonuclease P complex
Jedarce
mitohondrija
mitochondrial matrix
Biološki proces RNA phosphodiester bond hydrolysis
RNA phosphodiester bond hydrolysis, endonucleolytic
tRNA processing
tRNA 5'-leader removal
fatty acid metabolic process
lipid metabolism
fatty-acyl-CoA biosynthetic process
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001098783
NM_007042

NM_025938

RefSeq (bjelančevina)
NP_001092253
NP_008973
NP_001335641
NP_001335642
NP_001335643

NP_001335644

NP_080214

Lokacija (UCSC)Chr 3: 58.31 – 58.32 MbChr 14: 14.38 – 14.39 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Podjedinica p14 P-proteinske ribonukleaze jest enzim koji je kod ljudi kodiran genom RPP14 sa hromosoma 3.[5][6][7]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 124 aminokiseline, а molekulska težina 13.693 Da.[8]

1020304050
MPAPAATYERVVYKNPSEYHYMKVCLEFQDCGVGLNAAQFKQLLISAVKD
LFGEVDAALPLDILTYEEKTLSAILRICSSGLVKLWSSLTLLGSYKGKKC
AFRVIQVSPFLLALSGNSRELVLD

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163684 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023156 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jarrous N, Eder PS, Wesolowski D, Altman S (Mar 1999). "Rpp14 and Rpp29, two protein subunits of human ribonuclease P". RNA. 5 (2): 153–157. doi:10.1017/S135583829800185X. PMC 1369747. PMID 10024167.
  6. ^ Jiang T, Altman S (Apr 2002). "A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity". Proc Natl Acad Sci U S A. 99 (8): 5295–5300. doi:10.1073/pnas.072083699. PMC 122763. PMID 11929972.
  7. ^ "Entrez Gene: RPP14 ribonuclease P 14kDa subunit".
  8. ^ "UniProt, O95059" (jezik: engleski). Pristupljeno 5. 11. 2021.

Dopunska literatura

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Vanjski linkovi

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