n-Propyl azide is an organic compound with the formula CH3CH2CH2N3. A white solid, it is a simple organic azide. [1]

n-Propyl azide
Skeletal formula of propyl azide
Ball-and-stick model of the propyl azide molecule
Names
Preferred IUPAC name
1-Azidopropane
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C3H7N3/c1-2-3-5-6-4/h2-3H2,1H3 ☒N
    Key: TVPPZASKIXGUJQ-UHFFFAOYSA-N ☒N
  • InChI=1/C3H7N3/c1-2-3-5-6-4/h2-3H2,1H3
    Key: TVPPZASKIXGUJQ-UHFFFAOYAK
  • [N-]=[N+]=NCCC
Properties
C3H7N3
Molar mass 85.110 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Harmful, Explosive
Related compounds
Related compounds
Hydrazoic acid, Chlorine azide, Ethyl azide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

n-Propyl azide has been used in the laboratory synthesis of pharmaceutical drug candidates.[2][3]

References

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  1. ^ Stefan Bräse (Editor), Klaus Banert (Co-Editor); Organic Azides: Syntheses and Applications; 2010 John Wiley and Sons; ISBN 978-0-470-51998-1
  2. ^ Helmut Haning; et al. (2005). "Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitors". Bioorganic & Medicinal Chemistry Letters. 15 (17): 3900–3907. doi:10.1016/j.bmcl.2005.05.090. PMID 15993055.
  3. ^ Michael H. Parker; et al. (2002). "Synthesis of (−)-5,8-Dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: An Inhibitor of β-Amyloid1-42 Aggregation". Bioorganic & Medicinal Chemistry. 10 (11): 3565–3569. doi:10.1016/s0968-0896(02)00251-1. PMID 12213471.

Further reading

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