NFYC: Difference between revisions

NFYC
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N1J, 4AWL, 4CSR
Identifiers
Aliases	NFYC, CBF-C, CBFC, H1TF2A, HAP5, HSM, NF-YC, nuclear transcription factor Y subunit gamma
External IDs	OMIM: 605344; MGI: 107901; HomoloGene: 7440; GeneCards: NFYC; OMA:NFYC - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	40,771,603 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	120,688,769 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; apex of heart; ; muscle of thigh; ; monocyte; ; tendon of biceps brachii; ; right lobe of thyroid gland; ; right auricle; ; gastrocnemius muscle; ; ganglionic eminence; ; skin of abdomen;
	Top expressed in
	secondary oocyte; ; zygote; ; primary oocyte; ; genital tubercle; ; tail of embryo; ; thymus; ; heart; ; cerebellar cortex; ; bone marrow; ; olfactory bulb;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; transcription coactivator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription factor binding; sequence-specific DNA binding;
Cellular component	CCAAT-binding factor complex; protein-DNA complex; nucleus; nucleoplasm; RNA polymerase II transcription regulator complex;
Biological process	regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription by RNA polymerase II; protein folding; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; regulation of cholesterol biosynthetic process; negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	4802
	18046
	ENSG00000066136
	ENSMUSG00000032897
	Q13952
	P70353
NM_001142587; NM_001142588; NM_001142589; NM_001142590; NM_001308114;
	NM_001308115; NM_014223
NM_001048168; NM_001277095; NM_008692; NM_001357192; NM_001357193;
	NM_001357194
NP_001136059; NP_001136060; NP_001136061; NP_001136062; NP_001295043;
	NP_001295044; NP_055038
NP_001041633; NP_001264024; NP_032718; NP_001344121; NP_001344122;
	NP_001344123
	Wikidata
View/Edit Human	View/Edit Mouse

Browse history interactively

← Previous edit

Content deleted Content added

VisualWikitext

Inline

Latest revision as of 04:42, 15 January 2024

Nuclear transcription factor Y subunit gamma is a protein that in humans is encoded by the NFYC gene.^[5]^[6]^[7]

Function

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit (NFYB), a prerequisite for subunit A (NFYA) association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.^[7]

Two microRNAs; miR-30c and miR-30e are located within introns of the nfyc gene. These microRNAs are actively transcribed in human insulin-producing beta cells in the pancreatic islets that also show high expression of nfyc and CDH1 genes. The expression of these intronic microRNAs is essential for maintaining the differentiated phenotype of human islet beta cells. Inhibition of miR-30 family microRNAs induces epithelial-mesenchymal transition of human pancreatic islet cells.^[8]

Interactions

NFYC has been shown to interact with Myc.^[9]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000066136 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032897 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sinha S, Maity SN, Seldin MF, de Crombrugghe B (Feb 1997). "Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor". Genomics. 37 (2): 260–3. doi:10.1006/geno.1996.0555. PMID 8921405.
^ Bellorini M, Zemzoumi K, Farina A, Berthelsen J, Piaggio G, Mantovani R (Aug 1997). "Cloning and expression of human NF-YC". Gene. 193 (1): 119–25. doi:10.1016/S0378-1119(97)00109-1. PMID 9249075.
^ ^a ^b "Entrez Gene: NFYC nuclear transcription factor Y, gamma".
^ Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Mitnala S, Shouche Y, Hardikar AA (September–October 2009). "The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells". Islets. 1 (2): 137–147. doi:10.4161/isl.1.2.9578. PMID 21099261.
^ Taira T, Sawai M, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H (August 1999). "Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y". J. Biol. Chem. 274 (34): 24270–9. doi:10.1074/jbc.274.34.24270. PMID 10446203.

External links

NFYC+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000066136 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032897 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8921405-5] Sinha S, Maity SN, Seldin MF, de Crombrugghe B (Feb 1997). "Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor". Genomics. 37 (2): 260–3. doi:10.1006/geno.1996.0555. PMID 8921405.

[pmid9249075-6] Bellorini M, Zemzoumi K, Farina A, Berthelsen J, Piaggio G, Mantovani R (Aug 1997). "Cloning and expression of human NF-YC". Gene. 193 (1): 119–25. doi:10.1016/S0378-1119(97)00109-1. PMID 9249075.

[entrez-7] "Entrez Gene: NFYC nuclear transcription factor Y, gamma".

[Joglekar_2009-8] Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Mitnala S, Shouche Y, Hardikar AA (September–October 2009). "The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells". Islets. 1 (2): 137–147. doi:10.4161/isl.1.2.9578. PMID 21099261.

[pmid10446203-9] Taira T, Sawai M, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H (August 1999). "Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y". J. Biol. Chem. 274 (34): 24270–9. doi:10.1074/jbc.274.34.24270. PMID 10446203.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

@@ Line 1: / Line 1: @@
+{{cs1 config|name-list-style=vanc}}
-{{PBB|geneid=4802}}
+{{Short description|Protein-coding gene in the species Homo sapiens}}
-'''Nuclear transcription factor Y subunit gamma''' is a [[protein]] that in humans is encoded by the ''NFYC'' [[gene]].<ref name="pmid8921405">{{cite journal | author = Sinha S, Maity SN, Seldin MF, de Crombrugghe B | title = Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor | journal = Genomics | volume = 37 | issue = 2 | pages = 260–3 | year = 1997 | month = Feb | pmid = 8921405 | pmc =  | doi = 10.1006/geno.1996.0555 }}</ref><ref name="pmid9249075">{{cite journal | author = Bellorini M, Zemzoumi K, Farina A, Berthelsen J, Piaggio G, Mantovani R | title = Cloning and expression of human NF-YC | journal = Gene | volume = 193 | issue = 1 | pages = 119–25 | year = 1997 | month = Aug | pmid = 9249075 | pmc =  | doi =10.1016/S0378-1119(97)00109-1  }}</ref><ref name="entrez"/>
+{{Infobox_gene}}
+'''Nuclear transcription factor Y subunit gamma''' is a [[protein]] that in humans is encoded by the ''NFYC'' [[gene]].<ref name="pmid8921405">{{cite journal | vauthors = Sinha S, Maity SN, Seldin MF, de Crombrugghe B | title = Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor | journal = Genomics | volume = 37 | issue = 2 | pages = 260–3 | date = Feb 1997 | pmid = 8921405 | doi = 10.1006/geno.1996.0555 }}</ref><ref name="pmid9249075">{{cite journal | vauthors = Bellorini M, Zemzoumi K, Farina A, Berthelsen J, Piaggio G, Mantovani R | title = Cloning and expression of human NF-YC | journal = Gene | volume = 193 | issue = 1 | pages = 119–25 | date = Aug 1997 | pmid = 9249075 | doi = 10.1016/S0378-1119(97)00109-1 }}</ref><ref name="entrez"/>
 == Function ==
-The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved [[transcription factor]] that binds with high specificity to [[CAAT box|CCAAT]] motifs in the [[promoter (biology)|promoter]] regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit ([[NFYB]]), a prerequisite for subunit A ([[NFYA]]) association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a [[histone]]-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.<ref name="entrez">{{cite web | title = Entrez Gene: NFYC nuclear transcription factor Y, gamma| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4802| accessdate = }}</ref>
+The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved [[transcription factor]] that binds with high specificity to [[CAAT box|CCAAT]] motifs in the [[promoter (biology)|promoter]] regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit ([[NFYB]]), a prerequisite for subunit A ([[NFYA]]) association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a [[histone]]-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.<ref name="entrez">{{cite web | title = Entrez Gene: NFYC nuclear transcription factor Y, gamma| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4802}}</ref>
-Two [[microRNAs]]; miR-30c and miR-30e are located within [[introns]] of the ''nfyc'' gene.  These microRNAs are actively transcribed in human insulin-producing [[beta cell]]d\s in the [[pancreatic islets]] that also show high expression of nfyc and [[CDH1 (gene)|CDH1]] genes.  The expression of these intronic microRNAs is essential for maintaining the differentiated phenotype of human islet beta cells.  inhibition of miR-30 family microRNAs induces [[epithelial-mesenchymal transition]] of human pancreatic islet cells.<ref name="Joglekar_2009">{{cite journal | author = Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Mitnala S, Shouche Y, Hardikar AA | title = The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells | journal = Islets | year = 2009 | month = September/October | volume = 1 | issue = 2 | pages = 137-147 | doi=10.4161/isl.1.2.9578}}</ref>
+Two [[microRNA]]s; miR-30c and miR-30e are located within [[intron]]s of the ''nfyc'' gene.  These microRNAs are actively transcribed in human insulin-producing [[beta cell]]s in the [[Islets of Langerhans|pancreatic islets]] that also show high expression of nfyc and [[CDH1 (gene)|CDH1]] genes.  The expression of these intronic microRNAs is essential for maintaining the differentiated phenotype of human islet beta cells.  Inhibition of miR-30 family microRNAs induces [[epithelial-mesenchymal transition]] of human pancreatic islet cells.<ref name="Joglekar_2009">{{cite journal | vauthors = Joglekar MV, Patil D, Joglekar VM, Rao GV, Reddy DN, Mitnala S, Shouche Y, Hardikar AA | title = The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells | journal = Islets | volume = 1 | issue = 2 | pages = 137–147 | date = September–October 2009 | pmid = 21099261 | doi = 10.4161/isl.1.2.9578 | doi-access = free }}</ref>
-==Interactions==
+== Interactions ==
-NFYC has been shown to [[Protein-protein_interaction|interact]] with [[Myc]].<ref name="pmid10446203">{{cite journal | author = Taira T, Sawai M, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H | title = Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y | journal = J. Biol. Chem. | volume = 274 | issue = 34 | pages = 24270–9 | year = 1999 | month = August | pmid = 10446203 | doi = | url = | issn = }}</ref>
+NFYC has been shown to [[Protein-protein interaction|interact]] with [[Myc]].<ref name="pmid10446203">{{cite journal | vauthors = Taira T, Sawai M, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H | title = Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y | journal = J. Biol. Chem. | volume = 274 | issue = 34 | pages = 24270–9 | date = August 1999 | pmid = 10446203 | doi = 10.1074/jbc.274.34.24270 | doi-access = free }}</ref>
-==References==
+== References ==
 {{reflist}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
+* {{cite journal | vauthors = Mantovani R | title = The molecular biology of the CCAAT-binding factor NF-Y. | journal = Gene | volume = 239 | issue = 1 | pages = 15–27 | year = 1999 | pmid = 10571030 | doi = 10.1016/S0378-1119(99)00368-6 }}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Martinelli R, Heintz N | title = H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation. | journal = Mol. Cell. Biol. | volume = 14 | issue = 12 | pages = 8322–32 | year = 1994 | pmid = 7969168 | pmc = 359371 | doi =  10.1128/mcb.14.12.8322}}
-| citations =
-*{{cite journal  | author=Mantovani R |title=The molecular biology of the CCAAT-binding factor NF-Y. |journal=Gene |volume=239 |issue= 1 |pages= 15–27 |year= 1999 |pmid= 10571030 |doi=10.1016/S0378-1119(99)00368-6  }}
+* {{cite journal | vauthors = Nakshatri H, Bhat-Nakshatri P, Currie RA | title = Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated by cellular redox. | journal = J. Biol. Chem. | volume = 271 | issue = 46 | pages = 28784–91 | year = 1997 | pmid = 8910521 | doi = 10.1074/jbc.271.46.28784 | doi-access = free | hdl = 1805/18866 | hdl-access = free }}
-*{{cite journal  | author=Martinelli R, Heintz N |title=H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation. |journal=Mol. Cell. Biol. |volume=14 |issue= 12 |pages= 8322–32 |year= 1994 |pmid= 7969168 |doi=  | pmc=359371  }}
+* {{cite journal | vauthors = Dmitrenko V, Garifulin O, Kavsan V | title = Isolation and sequence analysis of the cDNA encoding subunit C of human CCAAT-binding transcription factor. | journal = Gene | volume = 197 | issue = 1–2 | pages = 161–3 | year = 1997 | pmid = 9332362 | doi = 10.1016/S0378-1119(97)00255-2 }}
-*{{cite journal  | author=Nakshatri H, Bhat-Nakshatri P, Currie RA |title=Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated by cellular redox. |journal=J. Biol. Chem. |volume=271 |issue= 46 |pages= 28784–91 |year= 1997 |pmid= 8910521 |doi=10.1074/jbc.271.46.28784  }}
+* {{cite journal | vauthors = Currie RA | title = Functional interaction between the DNA binding subunit trimerization domain of NF-Y and the high mobility group protein HMG-I(Y). | journal = J. Biol. Chem. | volume = 272 | issue = 49 | pages = 30880–8 | year = 1998 | pmid = 9388234 | doi = 10.1074/jbc.272.49.30880 | doi-access = free }}
-*{{cite journal  | author=Dmitrenko V, Garifulin O, Kavsan V |title=Isolation and sequence analysis of the cDNA encoding subunit C of human CCAAT-binding transcription factor. |journal=Gene |volume=197 |issue= 1-2 |pages= 161–3 |year= 1997 |pmid= 9332362 |doi=10.1016/S0378-1119(97)00255-2  }}
+* {{cite journal | vauthors = Taira T, Sawai M, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H | title = Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y. | journal = J. Biol. Chem. | volume = 274 | issue = 34 | pages = 24270–9 | year = 1999 | pmid = 10446203 | doi = 10.1074/jbc.274.34.24270 | doi-access = free }}
-*{{cite journal  | author=Currie RA |title=Functional interaction between the DNA binding subunit trimerization domain of NF-Y and the high mobility group protein HMG-I(Y). |journal=J. Biol. Chem. |volume=272 |issue= 49 |pages= 30880–8 |year= 1998 |pmid= 9388234 |doi=10.1074/jbc.272.49.30880  }}
+* {{cite journal | vauthors = Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, Mori K | title = Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response. | journal = Mol. Cell. Biol. | volume = 21 | issue = 4 | pages = 1239–48 | year = 2001 | pmid = 11158310 | pmc = 99577 | doi = 10.1128/MCB.21.4.1239-1248.2001 }}
-*{{cite journal  | author=Taira T, Sawai M, Ikeda M, ''et al.'' |title=Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y. |journal=J. Biol. Chem. |volume=274 |issue= 34 |pages= 24270–9 |year= 1999 |pmid= 10446203 |doi=10.1074/jbc.274.34.24270  }}
+* {{cite journal | vauthors = Izumi H, Molander C, Penn LZ, Ishisaki A, Kohno K, Funa K | title = Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor. | journal = J. Cell Sci. | volume = 114 | issue = Pt 8 | pages = 1533–44 | year = 2001 | doi = 10.1242/jcs.114.8.1533 | pmid = 11282029 }}
-*{{cite journal  | author=Yoshida H, Okada T, Haze K, ''et al.'' |title=Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response. |journal=Mol. Cell. Biol. |volume=21 |issue= 4 |pages= 1239–48 |year= 2001 |pmid= 11158310 |doi= 10.1128/MCB.21.4.1239-1248.2001  | pmc=99577 }}
+* {{cite journal | vauthors = Chen F, Ogawa K, Liu X, Stringfield TM, Chen Y | title = Repression of Smad2 and Smad3 transactivating activity by association with a novel splice variant of CCAAT-binding factor C subunit. | journal = Biochem. J. | volume = 364 | issue = Pt 2 | pages = 571–7 | year = 2002 | pmid = 12023901 | pmc = 1222603 | doi = 10.1042/BJ20011703 }}
-*{{cite journal  | author=Izumi H, Molander C, Penn LZ, ''et al.'' |title=Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor. |journal=J. Cell. Sci. |volume=114 |issue= Pt 8 |pages= 1533–44 |year= 2001 |pmid= 11282029 |doi=  }}
+* {{cite journal | vauthors = Romier C, Cocchiarella F, Mantovani R, Moras D | title = The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y. | journal = J. Biol. Chem. | volume = 278 | issue = 2 | pages = 1336–45 | year = 2003 | pmid = 12401788 | doi = 10.1074/jbc.M209635200 | doi-access = free }}
-*{{cite journal  | author=Chen F, Ogawa K, Liu X, ''et al.'' |title=Repression of Smad2 and Smad3 transactivating activity by association with a novel splice variant of CCAAT-binding factor C subunit. |journal=Biochem. J. |volume=364 |issue= Pt 2 |pages= 571–7 |year= 2002 |pmid= 12023901 |doi= 10.1042/BJ20011703  | pmc=1222603 }}
+* {{cite journal | vauthors = Salsi V, Caretti G, Wasner M, Reinhard W, Haugwitz U, Engeland K, Mantovani R | title = Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function. | journal = J. Biol. Chem. | volume = 278 | issue = 9 | pages = 6642–50 | year = 2003 | pmid = 12482752 | doi = 10.1074/jbc.M210065200 | doi-access = free | hdl = 11380/1202119 | hdl-access = free }}
-*{{cite journal  | author=Romier C, Cocchiarella F, Mantovani R, Moras D |title=The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y. |journal=J. Biol. Chem. |volume=278 |issue= 2 |pages= 1336–45 |year= 2003 |pmid= 12401788 |doi= 10.1074/jbc.M209635200 }}
+* {{cite journal | vauthors = Hirose T, Sowa Y, Takahashi S, Saito S, Yasuda C, Shindo N, Furuichi K, Sakai T | title = p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y. | journal = Oncogene | volume = 22 | issue = 49 | pages = 7762–73 | year = 2003 | pmid = 14586402 | doi = 10.1038/sj.onc.1207091 | s2cid = 1826456 | doi-access =  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
+* {{cite journal | vauthors = Chattopadhyay C, Hawke D, Kobayashi R, Maity SN | title = Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro. | journal = Nucleic Acids Res. | volume = 32 | issue = 12 | pages = 3632–41 | year = 2004 | pmid = 15243141 | pmc = 484179 | doi = 10.1093/nar/gkh692 }}
-*{{cite journal  | author=Salsi V, Caretti G, Wasner M, ''et al.'' |title=Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 6642–50 |year= 2003 |pmid= 12482752 |doi= 10.1074/jbc.M210065200 }}
+* {{cite journal | vauthors = Wang B, Gao C, Ponder KP | title = C/EBPbeta contributes to hepatocyte growth factor-induced replication of rodent hepatocytes. | journal = J. Hepatol. | volume = 43 | issue = 2 | pages = 294–302 | year = 2005 | pmid = 15922473 | doi = 10.1016/j.jhep.2005.02.029 }}
-*{{cite journal  | author=Hirose T, Sowa Y, Takahashi S, ''et al.'' |title=p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y. |journal=Oncogene |volume=22 |issue= 49 |pages= 7762–73 |year= 2003 |pmid= 14586402 |doi= 10.1038/sj.onc.1207091 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Chattopadhyay C, Hawke D, Kobayashi R, Maity SN |title=Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro. |journal=Nucleic Acids Res. |volume=32 |issue= 12 |pages= 3632–41 |year= 2004 |pmid= 15243141 |doi= 10.1093/nar/gkh692  | pmc=484179 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Wang B, Gao C, Ponder KP |title=C/EBPbeta contributes to hepatocyte growth factor-induced replication of rodent hepatocytes. |journal=J. Hepatol. |volume=43 |issue= 2 |pages= 294–302 |year= 2005 |pmid= 15922473 |doi= 10.1016/j.jhep.2005.02.029 }}
-}}
 {{refend}}
@@ Line 41: / Line 38: @@
 * {{MeshName|NFYC+protein,+human}}
-{{gene-1-stub}}
 {{NLM content}}
 {{PDB Gallery|geneid=4802}}
 {{Transcription factors|g0}}
 [[Category:Transcription factors]]
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{gene-1-stub}}
-{{PBB_Controls
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}

Latest revision as of 04:42, 15 January 2024

Function

Interactions

References

Further reading

External links

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.