Indenolol

Indenolol
Names
	IUPAC name 1-(1H-Inden-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
Identifiers
CAS Number	60607-68-3 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL153585;
ChemSpider	64962;
DrugBank	DB08952 ;
EC Number	262-323-5;
KEGG	D08078;
PubChem CID	71955;
UNII	3MZM7RWW00 ;
CompTox Dashboard (EPA)	DTXSID70866817 ;
	InChI InChI=1S/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3 Key: MPGBPFMOOXKQRX-UHFFFAOYSA-N; InChI=1/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3 Key: MPGBPFMOOXKQRX-UHFFFAOYAY;
	SMILES CC(C)NCC(COC1=CC=CC2=C1C=CC2)O;
Properties
Chemical formula	C15H21NO2
Molar mass	247.338 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Indenolol is a beta-adrenergic blocker^[1] for the treatment of hypertension (high blood pressure). It was investigated in the 1980s,^[2] but is not known to be marketed as of 2021^[update].^[3] It is a derivative of a phenolic 4-indenol.

References

^ Ali, I; Gaitonde, VD; Aboul-Enein, HY; Hussain, A (2009). "Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC". Talanta. 78 (2): 458–63. doi:10.1016/j.talanta.2008.11.043. PMID 19203609.
^ Trimarco, Bruno; Cuocolo, Alberto; Groothold, Gisela; Ricciardelli, Bruno; De Luca, Nicola; Volpe, Massimo; Veniero, Anna Maria; Condorelli, Mario (1985). "Indenolol: A New Antihypertensive Agent: Efficacy, Toxicity, and Hemodynamic Effects in a Crossover Double-Blind Study with Metoprolol". The Journal of Clinical Pharmacology. 25 (5): 328–336. doi:10.1002/j.1552-4604.1985.tb02850.x. PMID 4031109. S2CID 22844379.
^ DrugBank DB08952 . Accessed 2021-03-18.

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[1] Ali, I; Gaitonde, VD; Aboul-Enein, HY; Hussain, A (2009). "Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC". Talanta. 78 (2): 458–63. doi:10.1016/j.talanta.2008.11.043. PMID 19203609.

[2] Trimarco, Bruno; Cuocolo, Alberto; Groothold, Gisela; Ricciardelli, Bruno; De Luca, Nicola; Volpe, Massimo; Veniero, Anna Maria; Condorelli, Mario (1985). "Indenolol: A New Antihypertensive Agent: Efficacy, Toxicity, and Hemodynamic Effects in a Crossover Double-Blind Study with Metoprolol". The Journal of Clinical Pharmacology. 25 (5): 328–336. doi:10.1002/j.1552-4604.1985.tb02850.x. PMID 4031109. S2CID 22844379.

[3] DrugBank DB08952 . Accessed 2021-03-18.

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References

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