Oxprenoate potassium

Oxprenoate potassium
Clinical data
Other names	RU-28318; 17α-Hydroxy-3-oxo-7α-propylpregn-4-ene-21-carboxylic acid monopotassium salt
Drug class	Antimineralocorticoid
Identifiers
	IUPAC name potassium 3-[(7R,8R,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3-oxo-7-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate;
CAS Number	76676-34-1;
PubChem CID	23677972;
ChemSpider	64295;
UNII	167NDD8MTE;
CompTox Dashboard (EPA)	DTXSID401337179 ;
Chemical and physical data
Formula	C25H37KO4
Molar mass	440.665 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(CCC(=O)[O-])O)C.[K+];
	InChI InChI=1S/C25H38O4.K/c1-4-5-16-14-17-15-18(26)6-10-23(17,2)19-7-11-24(3)20(22(16)19)8-12-25(24,29)13-9-21(27)28;/h15-16,19-20,22,29H,4-14H2,1-3H3,(H,27,28);/q;+1/p-1/t16-,19+,20+,22-,23+,24+,25-;/m1./s1; Key:HXJITUGMCJCKCE-UYOQDFFISA-M;

Oxprenoate potassium (developmental code name RU-28318) is a synthetic steroidal antimineralocorticoid which was never marketed.^[1] The affinities of oxprenoate potassium for the steroid hormone receptors have been reported.^[2]

References

^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 922–. ISBN 978-1-4757-2085-3.
^ Raynaud JP, Fortin M, Hunt P, Ojasoo T, Doré JC, Surcouf E, Mornon JP, et al. (Fondation Princesse Liliane) (1986). "Approaches to drug development using receptors". In Gotto AM, O'Malley BW (eds.). The Role of Receptors in Biology and Medicine: Proceedings of the Ninth Argenteuil Symposium. Raven Press. pp. 65–77. ISBN 978-0-88167-161-2.

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