Karbetocin

Karbetocin
(IUPAC) ime
	(2S)-1-[(3S,6S,9S,12S,15S)-12-[(2S)-butan-2-yl]-; 9-(2-carbamoylethyl)-6-(carbamoylmethyl)-15-; [(4-hydroxyphenyl)methyl]-16-methyl-5,8,11,14,17-; pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane-; 3-carbonyl]-N-[(1S)-1-(carbamoylmethylcarbamoyl)-; 3-methyl-butyl]pyrrolidine-2-carboxamide
Klinički podaci
Identifikatori
CAS broj	37025-55-1
ATC kod	H01BB03
PubChem	71715
Hemijski podaci
Formula	C45H69N11O12S
Mol. masa	988.162 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C45H69N11O12S/c1-6-25(4)38-44(67)50-28(15-16-34(46)58)40(63)51-30(21-35(47)59)41(64)53-31(23-69-18-8-10-37(61)55(5)33(43(66)54-38)20-26-11-13-27(57)14-12-26)45(68)56-17-7-9-32(56)42(65)52-29(19-24(2)3)39(62)49-22-36(48)60/h11-14,24-25,28-33,38,57H,6-10,15-23H2,1-5H3,(H2,46,58)(H2,47,59)(H2,48,60)(H,49,62)(H,50,67)(H,51,63)(H,52,65)(H,53,64)(H,54,66)/t25-,28-,29-,30-,31-,32-,33-,38-/m0/s1 ; Key: SMMBGKXBHJTULT-DTRKZRJBSA-N
Farmakokinetički podaci
Bioraspoloživost	80% (IM)
Poluvreme eliminacije	40 minutes
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	POM (UK) nije dostupan u (SAD)
Način primene	Intravenous, intramuscular

Karbetocin (Duratocin) je akušerski lek koji se koristi za kontrolu krvarenja nakon porođaja.^[3] On je strukturni analog oksitocina, i njegovo dejstvo je slično oksitocinu, npr. kontrakcija materice.^[4]^[5]

Povezano

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ „Carbetocin Versus Syntometrine for the Third Stage of Labour”.
↑ „Carbetocin (Systemic)”. Arhivirano iz originala na datum 2014-09-29. Pristupljeno 2014-04-05.
↑ „Carbetocin may be more potent than oxytocin following c-section>”. Arhivirano iz originala na datum 2011-05-08. Pristupljeno 2014-04-05.

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