WAY-629

WAY-629
	1,2,3,4,8,9,10,11-Oktahidro[1,4]diazepino[6,7,1-jk]karbazol
Identifikacija
ChEMBL	CHEMBL258465
Jmol-3D slike	Slika 1
SMILES
	C1CCc2c(C1)c3cccc4CNCCn2c34
Svojstva
Molekulska formula	C15H18N2
Molarna masa	226,32 g mol-1
	; ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

WAY-629 je 5-HT_2C agonist za koji je putem eksperimenata na pacovima utvrđeno da umanjuje apetitit. On je korišten kao početna tačka za razvoj potentnih i selektivnih 5-HT_2C agonista za tretman gojaznosti.^[2]

Reference

↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Sabb, AL (May 2004). „Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor”. Bioorganic and Medicinal Chemistry Letters 14 (10): 2603–7. PMID 15109661.

Vanjske veze

Portal Hemija

[1] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[Sabb-2] Sabb, AL (May 2004). „Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor”. Bioorganic and Medicinal Chemistry Letters 14 (10): 2603–7. PMID 15109661.

[1]

[2]

Reference

Vanjske veze

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