IOLMaster 500 Defining biometry

The moment IOL power calculation becomes second nature. This is the moment we work for.

//IOLMaster 500
Made By Carl Zeiss
2 3

Efficiency Working with you

In a busy practice, throughput is key. For over a decade, we have partnered with surgeons, like you, to continue improving the gold standard in biometry. The IOLMaster 500 is the clear choice for effortless biometry that facilitates high-confidence IOL selection.1

//Efficiency
Made By Carl Zeiss

Mastery is achieved through constant refinement The IOLMaster 500 is dedicated to lowhassle biometry and high-confidence IOL selection. Designed for robustness, reliability and exceptional system integrity, the IOLMaster 500 offers a wide range of built-in IOL power calculation options, including the latest Haigis and Holladay 2 formulas.

High-speed biometry Minimize acquisition and chair time by performing accurate measurements quickly. In the Dual Mode, axial length and keratometry are captured in one measurement. Changeover between modes is completely automated and does not require any user interaction. The average time needed to take a reading on the IOLMaster 500 is up to 4 times faster compared to other optical devices.2 A difference you and your patients will notice every day.

Challenging patients Axial length and keratometry measurements with the IOLMaster 500 are fast and distance independent a great help in restless or poorly fixating patients. The IOLMaster 500 enables you to measure and calculate even pseudophakic, silicon-filled eyes or eyes with a phakic implant. The one-click selection of the correct eye status can be easily adapted even after data acquisition.

Best cataract penetration The IOLMaster 500 achieves a measurement success ratio that is up to 20 percent higher than that of other optical biometry devices. The underlying Composite Signal evaluation not only significantly increases the fraction of cataracts measurable with optical technology, it also greatly increases signal-to-noise values a measure of the outstanding reliability of the data the IOLMaster 500 provides.3,4,5

1) Leaming DV, 2010 Practice Styles and Preferences of U.S. ASCRS Members Survey 2) Chen YA, Hirnschall N, Findl O, Evaluation of 2 new optical biometry devices and comparison with the current gold standard biometer, J Cataract Refract Surg. 2011 Mar;37(3):513-517 3) Hill W, Angeles R, Otani T, Evaluation of a new IOLMaster algorithm to measure axial length. J Cataract Refract Surg. 2008 Jun;34(6):920-4. 4) Haigis W, Clinical Experience with the IOLMaster Advanced Technology software, presented at the ESCRS meeting in Stockholm, 2007 5) Olsen T, Improved clinical results with the IOLMaster Advanced Technology, presented at the ESCRS meeting in Stockholm, 2007 Changeover between modes is completely automated and does not require any user interaction Easier alignment through distance independent measurements of axial length and keratometry Composite signal evaluation for best cataract penetration in the industry

Simplicity Thinking with you

Based on years of experience working with you, the IOLMaster 500 has been designed to make your life simpler. The new platform provides efficient workflow, easy delegation and peace of mind.

//Simplicity
Made By Carl Zeiss

Intuitive and user-independent The IOLMaster 500 redefines simplicity. Its redesigned graphical user interface incorporates more than a decade of experience in optical biometry. It yields more data with fewer clicks. A great example of this superior usability is the Dual Mode, which facilitates measurements of axial length and keratometry without the need for manual interaction. A detailed evaluation and processing of the measurement results is possible at any time offering full transparency.

Confidence in meeting patient expectations Common sources of error are eliminated through an easy-to-understand traffic light indicator: a green light signals best alignment. With the integrated automatic mode, it is easy to delegate and trust the measurements. Right-eye and left-eye values for axial length and corneal radii are compared and checked for plausibility providing confidence especially for challenging eyes.

Most comprehensive set of formulas The IOLMaster 500 provides a comprehensive set of onboard IOL power calculation formulas. Included are fourth generation Haigis and Holladay 2.
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Post-LVC patients The number of cataract patients with prior laser vision correction (LVC) is growing rapidly. But often, clinical history data is not available. With its on-board Haigis-L formula, the IOLMaster 500 simplifies IOL power calculation in these cases no matter whether the refractive procedure was myopic or hyperopic.7

Seamlessly integrated IOL power calculations offer the shortest path to the result that really matters high confidence IOL power selection.

6) Holladay IOL Consultant software. http://www.hicsoap.com 7) Haigis W, Intraocular lens calculation after refractive surgery for myopia: Haigis-L formula. J Cataract Refract Surg. 2008 Oct;34(10):1658-63. Dual Mode enables one-click axial length and keratometry measurements IOLMaster 500 yields more data with fewer clicks Certainty at your fingertips: with the most comprehensive set of onboard IOL power calculation formulas The IOLMaster 500 simplifies IOL power calculation for patients with prior laser vision correction

Outcomes Calculating with you

90 % 80 % 70 % 60 % 50 % 40 % 30 % 20 % 10 % 0%

% of US Cataract Surgeons

You might have noticed the rising patient expectations in your Applanation Immersion practice: IOLMaster Other optical biometry devices Premium IOL patients and post-LVC patients are demanding cases. What could be more important in biometry than measurements you can rely on?
Preferred method of biometry
90 % 80 % 70 % 60 % 50 % 40 % 30 % 20 % 10 % 0% 80 % 70 % 60 % 50 % 40 % 30 % 20 % 10 % 0%
% of US Cataract Surgeons

2002

2003

2004

2005

2006

2007

2008

2009

2010

Preferred method of keratometry for routine IOL calculation The vast majority
67.8 59.2
70.6

% of US Cataract Surgeons

of cataract surgeons prefer the IOLMaster 500 for its accuracy

//OUTCOMES
Made By Carl Zeiss

24.9 17.9 16.4 10.7 8.8 6.7

2.2

and reliability8
5.2 10.5
4.0

2002

2003

2004
Immersion

2005

2006

2007

2008

2009

2010

Manual
2008 2009

Auto K
2010

IOLMaster

Applanation

IOLMaster

Other optical biometry devices

Other optical Topography/ biometry devices Corneal Analyzer

Precision counts In terms of accuracy and precision, the IOLMaster 500 satisfies the demands of
80 % 70 % 60 % 50 % 40 % 30 % 20 % 10 % 0%

Optimizing outcomes with integrated Holladay 2* You can continuously minimize your pre diction error for IOL power calculation on an individual basis. With the Holladay 2, now running on the IOLMaster 500, you just need to enter the postoperative refraction of your patients. All other data
10.5
4.0

Challenging eyes The true test of a biometer is its performance with challenging eyes. The IOLMaster 500 measures along the visual axis, yielding the relevant axial distance, even with staphyloma, pseudophakic and silicone-filled eyes. Calculation of phakic intraocular lenses is another growing need. A database of anterior and posterior phakic IOL types makes the selection of the appropriate dioptric power straightforward and reliable.

Post-LVC cases Eye care professionals are facing an increasing number of patients with prior laser vision correction (LVC). These patients can be a challenge when it comes to cataract diagnosis and treatment. The IOLMaster 500 includes the Haigis-L formula, which is dedicated to myopic and hyperopic post-LVC cases. As all formulas on the IOLMaster 500 the Haigis-L formula is scientifically proven.3 Haigis-L is especially convenient as it requires no clinical history data.

Continously optimizing lens constants with ULIB Any intraocular lens calculation is only as reliable as the lens constants it is based on. The extensive clinical history of the IOLMaster 500 is reflected by the Users Group for Interference Biometry (ULIB) website. For virtually all common IOL types, the ULIB database contains more than 160 lens constants optimized with over 30,000 sets of patient data created with the IOLMaster 500.11 These lens constants are continuously optimized and can easily be downloaded from the ULIB website onto your IOLMaster 500.

clinicians looking for optimal refractive

70.6 Signals of the outcomes. The Composite 67.8

% of US Cataract Surgeons

IOLMaster 500 facilitate the interpretation of axial length scans. With its solid 17.9 signal-to-noise ratio values of the
24.9 16.4 8.8 6.7 2.2 5.2 Composite Signal algorithm, dependable 10.7

59.2

is automatically fed into the Holladay 2 software calculation. There is no longer

6

data can be achieved for a

2008 2009 2010

Manual

Auto K

IOLMaster

Other optical Topography/ great number biometry devices Corneal Analyzer

of patients.

3,4,5

The user independence

a need to export data to the Holladay IOL Consultant software. Holladay 2 is now integrated into your IOLMaster 500. The IOLMaster 500 combines it all.
* Holladay 2 formula availabe for shipment in 2012.

and high reproducibility of IOLMaster 500 measurement results have been documented in the scientific literature.9

A-scan (immersion)
myopia hyperopia

Optical biometry (PCI)

myopia hyperopia 90% 80% 70% 60% 50% 40% 30% 20% 10% 0%

3) Hill W, Angeles R, Otani T, Evaluation of a new IOLMaster algorithm to measure axial length. J Cataract Refract Surg. 2008 Jun;34(6):920-4. 4) Haigis W, Clinical Experience with the IOLMaster Advanced Technology software, presented at the ESCRS meeting in Stockholm, 2007 5) Olsen T, Improved clinical results with the IOLMaster Advanced Technology, presented at the ESCRS meeting in Stockholm, 2007 6) Holladay IOL Consultant software. http://www.hicsoap.com 8) Leaming DV, 2010 Practice Styles and Preferences of U.S. ASCRS Members Survey 9) Vogel A, Dick HB, Krummenauer F., Reproducibility of optical biometry using partial coherence interferometry: intraobserver and interobserver reliability. J Cataract Refract Surg. 2001 Dec;27(12):1961-8. 11) User Group for Laser Interference Biometry. http://www.augenklinik.uni-wuerzburg.de/ulib/c1.htm
-1.0 0.0 1.0 -0.5 0.0 0.5 Spherical equivalent prediction error (D)

Proven accuracy and precision to meet rising patient expectations (data courtesy of Warren E. Hill, MD, FACS)

Reliable and accurate IOL power calculation for post-LVC patients with the Haigis-L formula

The ULIB for ZEISS IOLMaster: the latest set of continuously optimized IOLMaster 500 lens constants

IOLMaster 500 technical data

Measurement range Axial length 1438mm Corneal radii 510mm Interfaces Ultrasound data link (to Accutome A-Scan synergy) ZEISS data archive and review solution FORUM ZEISS OR management system CALLISTO eye Data interface for electronic medical record (EMR) / patient management systems (PMS) Data export to USB storage media Export database for Holladay IOL Consultant and HIC.SOAP Pro Ethernet port for network connection and network printer Line voltage Line frequency Performance consumption Laser class 100240 V 10% (self sensing) 5060Hz max. 75VA 1

Workflow Connecting with you

Product innovation at Carl Zeiss is guided by one overriding principle: We work to improve on what works best for your practice. Providing you with optimal connectivity solutions, you can concentrate on what matters most, your patients.

Anterior chamber depth 1.56.5mm White-to-white 816mm Display scaling Axial length 0.01mm Corneal radii 0.01mm Anterior chamber depth 0.01mm White-to-white 0.1mm IOL calculation formulas SRK II, SRK/T, Holladay 1 and 2, Hoffer Q, Haigis Clinical history and contact lens fitting method for calculation of corneal refractive power following refractive corneal surgery Haigis-L IOL calculation for eyes following myopic/hyperopic LASIK/PRK/LASEK surgery Calculation of phakic anterior and posterior chamber implants Optimization of IOL constants

Biometry workflow Well-designed user interfaces can help avoid user error and simplify operator training. The highly intuitive IOLMaster design has set standards for easyto-learn, easy-to-delegate biometry. The redesigned graphical user interface
Workflow efficiency with IOLMaster 500

Exporting IOLMaster 500 data to CALLISTO eye not only allows you to display IOLMaster 500 results on the OR Cockpit display, but also enables on-the-fly changes of the selected IOL. For connectivity with electronic medical records (EMR) and practice management systems, the IOLMaster 500 provides an interface based on the DICOM standard. Connecting ultrasound Previously, a patient not optically measurable meant a break in the workflow. With the Sonolink, the IOLMaster 500 easily connects to the Accutome A-Scan synergy ultrasound device. Ultrasound measurements with the A-Scan are quickly and easily imported into the IOLMaster 500 for IOL calculation. Patient data, measurements and calculation results are kept together in one database, and the risk of data entry errors is greatly reduced.12  All-in-one biometer: axial length and keratometry measurements as well as IOL power calculation in one device  Dual Mode: axial length and keratometry measurements without unnecessary manual interaction  Easy patient adjustments: distance independence of axial length and keratometry Composite Signal: for best-in-class cataract penetration  Flexible platform: automatic or manual mode for customized treatments  Robust platform: fully integrated system components, including formulas  One consistent graphical user interface: for all formulas, including Holladay 2  Most comprehensive set of formulas: includes fourth generation Haigis and Holladay 2  Holladay 2 onboard: incorporated into the IOLMaster 500 formula selection; no need to export data, reducing transcription errors Haigis-L formula: for post-LVC patients  Measurements along visual axis: for relevant axial distance, even in eyes with staphyloma  Measures challenging eyes: pseudophakic and siliconefilled eyes as well as eyes with phakic IOL  More comprehensive IOL calculation: for virtually all common IOL types Phakic IOL calculation: both anterior and posterior  ULIB database: contains continuously optimized IOL lens constants to improve refractive outcomes  Convenience: Sonolink for integrating Accutome A-Scan synergy ultrasound device Data integration: into FORUM data management system

IOLMaster 500 at a glance

continues this success story. It eliminates even more clicks and guides the user through an optimized workflow sequence. FORUM eye care data management The days of stand-alone instruments are over. The IOLMaster 500 fits perfectly into todays networked practice environments. It is part of the overall ZEISS data management solution FORUM, providing all relevant diagnostic data when it is needed and where it is needed. The IOLMaster 500 also seamlessly integrates with CALLISTO eye, the new ZEISS data management system for the operating

High-speed biometry workflow at any place

Easy connection to ultrasound

room.

12) Haigis W, Mlynski J, Comparative axial length measurements using optical and acoustic biometry in normal persons and in patients with retinal lesions, White Paper, Carl Zeiss Meditec, 2009

DICOM interface: for integration into EMR systems

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Your local contact: Argentina Carl Zeiss Argentina S.A. Calle Nahuel Huapi 4015 / 25 C1430 BCO Buenos Aires Argentina Phone: +54 11 45 45 66 61 bruzzi@zeiss.com.ar Australia Carl Zeiss Pty. Ltd. Unit 13, 2 Eden Park Drive North Ryde, New South Wales 2113 Australia Phone: +61 2 9020 1333 med@zeiss.com.au Austria Carl Zeiss GmbH Laxenburger Str. 2 1100 Vienna Austria Phone: +43 1 79 51 80 austria@zeiss.org Belgium Carl Zeiss NV-SA Ikaroslaan 49 1930 Zaventem Belgium Phone: +32 2 719 39 11 info@zeiss.be Brazil Carl Zeiss do Brasil Ltda. Av. Naoes Unidas, 21711 CEP04795-100 So Paulo Brazil Phone: +55 11 5693 5521 medbrasil@zeiss.org Canada Carl Zeiss Canada Ltd. 45 Valleybrook Drive Toronto, ON M3B 2S6 Canada Phone: +1 800 387 8037 micro@zeiss.com China Carl Zeiss Shanghai Co. Ltd. 1/f., Ke Yuan Building 11 Ri Yin Nan Road Waigaoqiao Free Trade Zone 2005 Yang Gao Bei Road Shanghai 200131 China Phone: +86 21 5048 17 17 sro@zeiss.com.cn

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Malaysia Carl Zeiss Sdn Bhd. Lot2, Jalan 243/51 A 46100 Petaling Jaya Selangor Darul Ehsan Malaysia Phone: +60 3 7877 50 58 malaysia@zeiss.com.sg Mexico Carl Zeiss de Mxico S.A. de C.V. Avenida Miguel Angel de Quevedo 496 04010 Mexico City Mexico Phone: +52 55 59 99 0200 cz-mexico@zeiss.org Netherlands Carl Zeiss B.V. Trapezium 300 Postbus 310 3364 DL Sliedrecht Netherlands Phone: +31 184 43 34 00 info@zeiss.nl New Zealand Carl Zeiss (N.Z.) Ltd. 15B Paramount Drive P.O. Box 121 - 1001 Henderson, Auckland 0650 New Zealand Phone: +64 9 838 5626 med@zeiss.com.au Poland Carl Zeiss sp. Z o.o. ul. Lopuszanska 32 02-220 Warsaw Poland Phone: +48 22 858 2343 medycyna@zeiss.pl Singapore Carl Zeiss Ptd. Ltd. 50 Kaki Bukit Place Singapore 415926 Singapore Phone: +65 6741 9600 info@zeiss.com.sg South Africa Carl Zeiss (Pty.) Ltd. 363 Oak Avenue Ferndale Randburg 2194 South Africa Phone: +27 11 886 9510 info@zeiss.co.za

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0297

Manufacturer:

Carl Zeiss Meditec AG Goeschwitzer Strasse 5152 07745 Jena Germany www.meditec.zeiss.com/iolmaster

Publication No: 000000-1966-318 IOL.3905 The contents of the brochure may differ from the current status of approval of the product in your country. Please contact our regional representative for more information. Subject to change in design and scope of delivery and as a result of ongoing technical development. Printed on elemental chlorine-free bleached paper. 2011 by Carl Zeiss Meditec AG. All copyrights reserved.