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OB Drug Study

Gentamicin is an aminoglycoside antibiotic given intravenously every 8 hours to treat serious infections. It works by inhibiting bacterial protein synthesis. Common side effects include upset stomach, vomiting, and fatigue. Nurses monitor for allergic reactions, check culture results, and assess for signs of infection. Clindamycin is a lincosamide antibiotic given intravenously every 8 hours to treat infections caused by susceptible anaerobic bacteria. It works by binding to the 50S ribosomal subunit and inhibiting bacterial protein synthesis. Potential side effects include diarrhea, nausea, and allergic reactions. Nurses obtain cultures prior to treatment, monitor the bowel, and assess for signs of infection and hypersensitivity.

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0% found this document useful (0 votes)
409 views5 pages

OB Drug Study

Gentamicin is an aminoglycoside antibiotic given intravenously every 8 hours to treat serious infections. It works by inhibiting bacterial protein synthesis. Common side effects include upset stomach, vomiting, and fatigue. Nurses monitor for allergic reactions, check culture results, and assess for signs of infection. Clindamycin is a lincosamide antibiotic given intravenously every 8 hours to treat infections caused by susceptible anaerobic bacteria. It works by binding to the 50S ribosomal subunit and inhibiting bacterial protein synthesis. Potential side effects include diarrhea, nausea, and allergic reactions. Nurses obtain cultures prior to treatment, monitor the bowel, and assess for signs of infection and hypersensitivity.

Uploaded by

vanni213
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Generic/ Trade Dosage/ Mechanism of Indication Contraindication Side Effects Nursing

Name/ Frequency Action Responsibilities


Classification

Generic Name: 80mg/IV Gentamicin For Serious - Hypersensitivity • upset stomach - Check for patients
every 8 inhibits bacterial infections if the to history
Gentamicin hours protein synthesis GI, Respiratory, aminoglycosides • vomiting
Sulfate mainly through Urinary Tracts, - Check for allergic
binding with the CNS, Bones, - Bacterial and • fatigue reactions
Brand Name: 30S ribosomal Skin, and soft fungal corneal
subunit, and acts Tissues including ulcers have •pale skin - Check for Culture
through two burns when developed during and Sensitivity test
Classification: different other less toxic treatment with result
mechanisms.  In antimicrobial gentamicin
Antibiotics/ one mechanism, agents are -Instruct the patient
Aminoglycosides gentamicin can ineffective or are to take a rest to
interfere with contraindicated prevent fatigue
the correct
amino acid
polymerization
and elongation.
Generic/ Trade Dosage/ Mechanism of Indication Contraindication Side Effects Nursing
Name/ Frequency Action Responsibilities
Classification
- Assess for infection
Generic Name: 900mg/IV Reversibly binds infections - Hypersensitivity CV: Hypotension, (vital signs;
every 8 to 50S ribosomal caused by to clindamycin cardiac arrest appearance of wound,
Clindamycin Hcl hours subunits susceptible (with rapid IV sputum, urine, and
preventing anaerobic or infusion) stool;
Brand Name: peptide bond gram + aerobic WBC) at beginning
formation thus bacteria: Upper GI: Severe colitis, and throughout
Classification: inhibiting & including therapy.
bacterial protein lower pseudomembran
Antibiotics synthesis; respiratory tract, ous colitis, - Obtain specimens for
bacteriostatic or skin & soft nausea, vomiting, culture and sensitivity
bactericidal tissue, bone & diarrhea, prior to initiating
depending on joint, abdominal pain, therapy.
drug gynecological, esophagitis,
concentration, intra- abdominal anorexia, - Monitor bowel
infection site, infections, jaundice, liver elimination.
and organism. septicemia & function changes
endocarditis, -Assess patient for
dental Hypersensitivity: hypersensitivity (skin
infections. Rashes, urticaria rash, urticaria).
to anaphylactoid
reactions - Monitor CBC

- Take each dose with


a full glass of water
(decreases esophageal
iritiation)
Generic/ Trade Dosage/ Mechanism of Indication Contraindication Side Effects Nursing
Name/ Frequency Action Responsibilities
Classification

Generic Name: 2gms/IV Inhibits bacterial Used for treating Hypersensitivity - Nausea - Check for patients
every 6 cell bacterial to ampicillin, any history
Ampicillin hours wall synthesis by infection. component of the - Vomiting
binding to one formulation, or - Check for allergic
Brand Name: or other penicillins - Loss of reactions
more of the appetite
Omniphen penicillin - Check for Culture
binding proteins - Diarrhea and Sensitivity test
Classification: (PBPs); which in result
turn inhibits the - Abdominal
Antibiotics/ final pain - Take each dose with
penicillin transpeptidation a full glass of water
step - Rash (decreases esophageal
of peptidoglycan iritiation)
synthesis in - Itching
bacterial - Instruct client to
cell walls, thus - Headache report any adverse
inhibiting cell reaction to the
wall - Confusion physician
biosynthesis. or nurse
- Dizziness
Generic/ Trade Dosage/ Mechanism of Indication Contraindication Side Effects Nursing
Name/ Frequency Action Responsibilities
Classification

Generic Name: 1 amp/IV Reduces fever Used for the Contraindicated - Chest pain - Check for patients
every 6 by acting on the relief of with history
Paracetamol hours/PRN hypothalamus fever, allergy to - Dyspnea
to cause headaches, and acetaminophen - check for allergic
Brand Name: vasodilatation other and pains or any - Rash reactions
& sweating. regarding component.
surgical Use cautiously - Fever - Monitor signs of
Classification: wound. with hepatotoxicity
impaired hepatic - Jaundice
Antipyretic/ function, chronis - do not give other
Analgesic alcoholism, and - Hepatic failure drugs that contains
pregnancy acetaminophen
lactation
Generic/ Trade Dosage/ Mechanism of Indication Contraindication Side Effects Nursing
Name/ Frequency Action Responsibilities
Classification

Generic Name: 500 mg/IV After diffusing Used for treating Hypersensitivity to Allergic - Check for patients
every 6 into bacterial metronidazole, reaction: history
Metronidazole hours the organism, infection and nitroimidazole hives, difficulty
interacts with also protozoal derivatives, or any in breathing, - check for allergic
Brand Name: DNA infestation component of the swelling of reactions
to cause a loss of formulation; face, lips,
Flagyl helical DNA pregnancy tongue, or throat - Monitor Vital signs
structure and
Classification: strand breakage Serious Side - appearance of urine,
resulting in Effects: stool and also WBC
Antiprotozoal/ inhibition of seizures
Antibacterial protein synthesis (convulsions), - Monitor neurological
and cell death in fever, flu signs before and after
susceptible symptoms, IV infusion
organisms white patches
or sores inside - Monitor I&O and
your mouth or weight
on your lips,
pain or burning
when you
urinate,
diarrhea that is
watery or
bloody.

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