1.) Generic Name: Gabapentin Brand Name Classification Dosage Route and Frequency Mechanism of Action
1.) Generic Name: Gabapentin Brand Name Classification Dosage Route and Frequency Mechanism of Action
NURSING RESPONSIBILITIES
Monitor for therapeutic effectiveness; may not occur until several weeks following
initiation of therapy.
Assess frequency of seizures: In rare cases, the drug has increased the
frequency of partial seizures.
Assess safety: Vision, concentration, and coordination may be impaired by
gabapentin.
2.) GENERIC NAME: TRAMADOL HYDROCHLORIDE
BRAND NAME: Ultram, Zydol
CLASSIFICATION: CENTRAL NERVOUS SYSTEM (CNS)
AGENT; ANALGESIC; NARCOTIC (OPIATE) AGONIST
DOSAGE: 1 tab
ROUTE AND FREQUENCY: Three times a day for 5 days - Oral
MECHANISM OF ACTION:
Centrally acting opiate receptor agonist that inhibits the uptake of norepinephrine and
serotonin, suggesting both opioid and nonopioid mechanisms of pain relief. May
produce opioid-like effects, but causes less respiratory depression than morphine.
INDICATION:
Management of moderate to moderately severe pain.
CONTRAINDICATION:
Hypersensitivity to tramadol or other opioid analgesics; patients on MAO inhibitors;
patients acutely intoxicated with alcohol, hypnotics, centrally acting analgesics, opioids,
or psychotropic drugs; substance abuse; patients on obstetric preoperative medication;
abrupt discontinuation; alcohol intoxication; pregnancy (category C); lactation; children
<16 y.
ADVERSE EFFECT:
CNS: Drowsiness, dizziness, vertigo, fatigue, headache,
somnolence, restlessness, euphoria, confusion, anxiety, coordination
disturbance, sleep disturbances, seizures.
CV: Palpitations, vasodilation.
GI: Nausea, constipation, vomiting, xerostomia, dyspepsia, diarrhea, abdominal
pain, anorexia, flatulence.
Body as a Whole: Sweating, anaphylactic reaction (even with first dose),
withdrawal syndrome (anxiety, sweating, nausea, tremors, diarrhea, piloerection,
panic attacks, paresthesia, hallucinations) with abrupt discontinuation.
Skin: Rash. Special Senses: Visual disturbances.
Urogenital: Urinary retention/frequency, menopausal symptoms.
NURSING RESPONSIBILITIES
Assess for level of pain relief and administer prn dose as needed but not to
exceed the recommended total daily dose.
Monitor vital signs and assess for orthostatic hypotension or signs of CNS
depression.
Discontinue drug and notify physician if S&S of hypersensitivity occur.
Assess bowel and bladder function; report urinary frequency or retention.
Use seizure precautions for patients who have a history of seizures or who are
concurrently using drugs that lower the seizure threshold.
Monitor ambulation and take appropriate safety precautions.
Ask the parent of the patient to notify any of the health care team if the patient
vomits of having abdominal pain
Monitor for signs and symptoms of adverse reaction.
NURSING RESPONSIBILITIES
In children if the initial dose causes diarrhea, dosage is reduced immediately.
Discontinue if diarrhea persists.
Promote fluid intake ( 1500–2000 mL/d) during drug therapy for constipation;
older adults often self-limit liquids. Lactulose-induced osmotic changes in the
bowel support intestinal water loss and potential hypernatremia. Discuss strategy
with physician.
Laxative action is not instituted until drug reaches the colon; therefore, about 24–
48 h is needed.
Do not self-medicate with another laxative due to slow onset of drug action.
Notify physician if diarrhea (i.e., more than 2 or 3 soft stools/d) persists more
than 24–48 h. Diarrhea is a sign of overdosage. Dose adjustment may be
indicated.
.
ADVERSE EFFECT:
GI: Nausea, heartburn, anorexia, constipation, diarrhea, epigastric pain, abdominal
distress, black stools.
Special Senses: Yellow-brown discoloration of eyes and teeth (liquid forms.) Large
Chronic Doses in Infants Rickets (due to interference with phosphorus
absorption). Massive Overdosage Lethargy, drowsiness, nausea, vomiting, abdominal
pain, diarrhea, local corrosion of stomach and small intestines, pallor or cyanosis,
metabolic acidosis, shock, cardiovascular collapse, convulsions, liver necrosis, coma,
renal failure, death.
NURSING RESPONSIBILITIES
note: ascorbic acid increases absorption of iron. consuming citrus fruit or tomato
juice with iron preparation (except the elixir) may increase its absorption.
be aware that milk, eggs, or caffeine beverages when taken with the iron
preparation may inhibit absorption.
be aware that iron preparations cause dark green or black stools.
report constipation or diarrhea to physician; symptoms may be relieved by
adjustments in dosage or diet or by change to another iron preparation.
ADVERSE EFFECT:
GI: Nausea, vomiting, diarrhea, cramps, gas, pseudomembranous colitis.
Metabolic: Transient increases in liver transaminases, alkaline phosphatase, lactic
dehydrogenase, and eosinophilia count.
Musculoskeletal: Tendon rupture, cartilage erosion.
CNS: Headache, vertigo, malaise, peripheral neuropathy, seizures (especially with rapid
IV infusion).
Skin: Rash, phlebitis, pain, burning, pruritus, and erythema at infusion site.
Special Senses: Local burning and discomfort, crystalline precipitate on superficial
portion of cornea, lid margin crusting, scales, foreign body sensation, itching, and
conjunctival hyperemia.
NURSING RESPONSIBILITIES
Report tendon inflammation or pain. Drug should be discontinued.
Lab tests: Culture and sensitivity tests should be done prior to initial dose.
Treatment may be implemented pending results.
Monitor urine pH; it should be less than 6.8, especially in the older adult and
patients receiving high dosages of ciprofloxacin, to reduce the risk of crystalluria.
Monitor I&O ratio and patterns: Patients should be well hydrated; assess for S&S
of crystalluria.
Monitor plasma theophylline concentrations, since drug may interfere with half-
life.
Administration with theophylline derivatives or caffeine can cause CNS
stimulation.
Assess for S&S of GI irritation (e.g., nausea, diarrhea, vomiting, abdominal
discomfort) in clients receiving high dosages and in older adults.
Monitor PT and INR in patients receiving coumarin therapy.
Assess for S&S of superinfections
NURSING RESPONSIBILITIES
Determine previous hypersensitivity reactions to penicillins, cephalosporins, and
other allergens prior to therapy.
Lab tests: Baseline C&S tests prior to initiation of therapy; start drug pending
results. Baseline and periodic assessments of renal, hepatic, and hematologic
functions, particularly during prolonged or high-dose therapy.
Note: Sodium content of drug must be considered in patients on sodium
restriction.
Inspect skin daily and instruct patient to do the same. The appearance of a rash
should be carefully evaluated to differentiate a nonallergenic ampicillin rash from
a hypersensitivity reaction. Report rash promptly to physician.
Note: Incidence of ampicillin rash is higher in patients with infectious
mononucleosis or other viral infections, Salmonella infections, lymphocytic
leukemia, or hyperuricemia or in patients taking allopurinol.
Take medication around the clock; continue taking medication until it is all gone
(usually 10 d) unless otherwise directed by physician or pharmacist.
CONTRAINDICATION:
Hypersensitivity to levofloxacin and quinolone antibiotics; hypokalemia, tendon pain,
pregnancy (category C); syphilis; viral infections; phototoxicity; lactation.
ADVERSE EFFECT:
CNS: Headache, insomnia, dizziness.
GI: Nausea, diarrhea, constipation, vomiting, abdominal pain, dyspepsia.
Skin: Rash, pruritus.
Special Senses: Decreased vision, foreign body sensation, transient ocular
burning, ocular pain, photophobia. Urogenital: Vaginitis.
Body as a Whole: Injection site pain or inflammation, chest or back pain, fever,
pharyngitis.
Other: Cartilage erosion.
NURSING RESPONSIBILITIES
Lab tests: Do C&S test prior to beginning therapy and periodically.
Withhold therapy and report to physician immediately any of the following: Skin
rash or other signs of a hypersensitivity reaction (see Appendix F); CNS
symptoms such as seizures, restlessness, confusion, hallucinations, depression;
skin eruption following sun exposure; symptoms of colitis such as persistent
diarrhea; joint pain, inflammation, or rupture of a tendon; hypoglycemic reaction
in diabetic on an oral hypoglycemic agent.
ADVERSE EFFECT:
Significant: Visual and ocular disturbance (e.g. impaired colour vision), retinal
vein or artery occlusion, ligneous conjunctivitis, thromboembolic events,
convulsions.
NURSING RESPONSIBILITIES
Check IV site at frequent intervals for extravasation.
Observe for signs of thrombophlebitis. Change site immediately if extravasation
or thrombophlebitis occurs (see Appendix F).
Monitor & report S&S of myopathy: muscle weakness, myalgia, diaphoresis,
fever, reddish-brown urine (myoglobinuria), oliguria, as well as thrombotic
complications: arm or leg pain, tenderness or swelling, Homan's sign,
prominence of superficial veins, chest pain, breathlessness, dyspnea. Drug
should be discontinued promptly.
Monitor vital signs and urine output.
Lab tests: with prolonged therapy, monitor creatine phosphokinase activity and
urinalyses for early detection of myopathy.
ADVERSE EFFECT:
Significant: Shock, anaphylaxis reactions (e.g. redness, itching, urticaria,
oedema, dypnoea), Stevens-Johnson syndrome and toxic epidermal necrolysis.
Blood and lymphatic system disorders: Anaemia.
Cardiac disorders: Palpitations.
Gastrointestinal disorders: Nausea, vomiting, stomach discomfort, abdominal
pain, diarrhoea, constipation, stomatitis, feeling of enlarged abdomen, hiccup.
General disorders and admin site conditions: Weakness, fatigue, diaphoresis.
Investigations: Elevated BUN.
Metabolism and nutrition disorders: Anorexia, thirst.
Musculoskeletal and connective tissue disorders: Stiffness, muscle
hypotonia.
Nervous system disorders: Headache, numbness of extremities, tremor, light-
headedness, dizziness.
Psychiatric disorders: Sleepiness, insomnia.
Renal and urinary disorders: Proteinuria, urinary retention, urinary
incontinence.
Skin and subcutaneous tissue disorders: Rash, pruritus, erythema exudative
multiforme.
Vascular disorders: Hot flushes.
NURSING RESPONSIBILITIES
Be aware that incidence and severity of adverse effects are usually dose related
and may be minimized by dosage reduction. Older adults appear more sensitive
to usual adult doses.
Monitor vital signs. Pulse is a particularly sensitive indicator of response to drug.
Report tachycardia, palpitations, paradoxical bradycardia, or fall in BP.
Assess for and report severe CNS stimulation (see ADVERSE EFFECTS) that
occurs with high doses, and in patients with arteriosclerosis, or those with history
of hypersensitivity to other drugs.
In patients with severe rigidity, tremors may appear to be accentuated during
therapy as rigidity diminishes.
Monitor daily I&O if patient develops urinary hesitancy or retention. Voiding
before taking drug may relieve problem.
Check for abdominal distention and bowel sounds if constipation is a problem.
Monitor intraocular pressure at regular intervals.
Provide close follow-up care. Tolerance may develop, necessitating dosage
adjustment or use of combination therapy. Patients 60 y frequently develop
sensitivity to drug action.
BLOOD TRANSFUSION
Date: January 11, 2020 @ 2300H
BLOOD TRANSFUSION
Date: January 11,2020 @ 2330H
BLOOD TRANSFUSION
Date: January 11, 2020 @2330H
BLOOD TRANSFUSION
Date: January 13, 2020 @1730H
BLOOD TRANSFUSION
Date: January 14, 2020
BLOOD TRANSFUSION
Date: January 21, 2020 @2200H