CEFUROXIME Scribd
CEFUROXIME Scribd
Nursing
Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects
Responsibilities
Generic Name: Therapeutic Inhibits bacterial cell Pharyngitis Contraindicated with CNS: Headache, Before:
Cefuroxime Classification: anti- wall synthesis by Tonsillitis allergy to dizziness, lethargy, Check doctor’s order
infectives binding to one or more Infection of the cephalosporins or paresthesia Assess skin status,
Trade Name: Ceftin of the penicillin-binding urinary and lower penicillins. GI: Nausea, vomiting, renal function tests,
Pharmacological proteins (PBPs) which respiratory tracts Use cautiously with diarrhea, anorexia, hx of hypersensitivity
Px’s dose: 500 mg BID Classification: in turn inhibits the final Skin and skin renal failure, abdominal pain, Verify px’s identity
PO antibiotic, second- transpeptidation step of structure lactation, pregnancy. flatulence, pseudo Explain the right
generation peptidoglycan synthesis infections cause by membranous colitis, dosage, full course of
Availability: Tablets cephalosporin in bacterial cell walls, Streptococcus hepatotoxicity medication, use of
125 mg, 250 mg. 500 thus inhibiting cell wall pneumoniae and S. GU: Nephrotoxicity drug and side effects
mg Pregnancy Category: B biosynthesis. Bacteria pyogenes, Hematologic: Bone
eventually lyse due to Haemophillus marrow depression (low During:
Route: Oral ongoing activity of cell influenza, WBC, low platelets, low Give oral drug with
wall autolytic enzymes staphylococcus HCT) food to decrease GI
(autolysins and murein aureus, Hypersensitivity: from upset and enhance
hydrolases) while cell Escherichia coli rash to fever to absorption
wall assembly is UTIs caused by anaphylaxis; serum Have Vit K available
arrested. Escherichia coli, sickness reaction incase
Klebsiella Other: Superinfections, ofhypothrombinemia
pneumoniae disulfiram-like reaction occurs
Uncomplicated with alcohol Take full course of
Pharmacokinetics: gonorrhea therapy even if you
Metabolism: T ½: 1- are feeling better
Treatment of early
2hr Lyme disease This drug is specific
Distribution: crosses for this infection and
placenta; enters breast should not be used to
milk
Excretion: urine self-threat other
Onset: IV- rapid, IM- problems
20mins, O-varies Swallow the tablets
Peak: immediate; whole do not crush
30mins;2hr them.
Duration:18-24hr
After:
Discontinue if
hypersensitivity
reaction occurs
Report severe
diarrhea with blood,
pus or mucus; rash;
difficulty breathing;
unusual tiredness,
fatigue; unusual
bleeding or bruising;
unusual itching or
irritation
Report for allergic
rxn
Emphasize drug
compliance
Source: Karch, Amy Source: Karch, Amy Source: Karch, Amy Source: Karch, Amy Source: Karch, Amy Source: Karch, Amy Source: Karch, Amy
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