Saint Louis University

SCHOOL OF NATURAL SCIENCES

Department of PHARMACY

REF SNS-BSPharm-PHARM 215-2020

BACHELOR OF SCIENCE IN PHARMACY

Course No.: Course Title

1 Name of Course Pharmacology And Therapeutics 2

2 Course Number PHARM 315
3 Semester and Year
Offered
4 Credit Units 1st Semester, 3rd year
5 Contact Hours 3 Units Lecture; 1 unit Laboratory
6 Pre-requisite/s (if any) 54 hours Lecture; 18 hours Laboratory
7 Co-requisite/s (if any)
8 Course Description This course is a continuation of Pharmacology and Therapeutics 1. It further discusses the pharmacokinetics and
pharmacodynamics of drugs that affect the cardiovascular, respiratory, gastro-intestinal, endocrine and genito-
urinary systems. Additionally, drugs used in the management of immunologic, oncologic and infectious conditions
are also discussed extensively. It also deals with the adverse effects, dosage regimen, contraindications and
interactions of these drugs.
9 Program Learning After finishing the BS Pharmacy program, the graduate should be able to:
Outcomes 1. Participate in the generation of new knowledge and development projects and researches and disseminate
findings for utilization.
2. Utilize techno-intelligent care systems and processes in health care delivery.
3. Engage in lifelong learning with a passion to keep current with national and global developments, as well
as, pharmacy and health developments.
4. Communicate and facilitate learning effectively of selected learners for specific purpose (patients,
students, peers, staff and health professionals) in speaking, writing and presenting using culturally-
appropriate language.
5. Work effectively in collaboration with with inter-, intra-, and multi-disciplinary and multi-cultural teams.
6. Practice pharmacy in accordance with existing laws, legal, ethical and moral principles
7. Integrate knowledge & skills of mathematics, physical, social, natural and health sciences, humanities,
environmental, information technology & other advanced technologies in pharmacy practice.
8. Perform safe, appropriate, humanistic and holistic care to individuals, families, population groups and
community utilizing the pharmaceutical care process.
9. Practice efficiently and effectively key responsibilities (managerial & entrepreneurial skills) in any
organization integrating patient safety.
10. Demonstrate responsible citizenship and pride in being a Filipino Louisian Pharmacist.
11. Apply suitable guidelines, principles and techniques of evidence-based practice in the delivery of
pharmaceutical care.
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

12. Practice Christian values in their personal and professional endeavors as Louisians in the service of the
CICM mission.
10 Course Learning After completing this course, the would- be pharmacists should be able to:
Outcomes 1. List specific drugs that are rationally used in the treatment of cardiovascular, pulmonary, gastro-intestinal,
hormonal and hematologic diseases; as well as chemotherapeutic agents for infectious diseases.
2. Explain the occurrence of adverse effects associated with the use of chemotherapeutic agents.
3. Perform in-vitro procedures to determine the pharmacological activities of drug substances.
4. Administer drug substances to laboratory animals to determine the drugs’ pharmacological activities.
5. Perform laboratory procedures to determine safety and toxicological data of drugs on animals.
6. Extrapolate data on laboratory animals to determine drug response of human subjects.

11. Alignment of Course Learning Outcomes with the SLU Graduate Attributes

SLU Graduate Attributes Course Learning Outcomes

Christian Spirited CLO1, CLO5
Socially Involved CLO6
Professionally Competent CLO1, CLO2, CLO3, CLO4, CLO5, CLO6
Creative and Critical Thinker CLO3, CLO4, CLO5, CLO6

12. Learning Plan

Topic Conten T Learning Assessm

Learning t/Topic A Strategies ent
Outcomes

PRELIMS

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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

At the end of I. Review of Lecture Graded

this chapter, the Pharmacol 2 Class discussion recitation
student should ogy1 ho (review of Diagnostic
be able to: urs Pharmacology 1) exam
1. Recall the A. Concepts
definition, on Drugs
sources, B. Pharmac
categories, okinetics
dosage and
forms and Pharmac
routes of odynami
administra cs
tion of C. Drugs
drugs; acting on
2. Explain the
the Nervous
absorption System
,
distributio
n,
metabolis
m and
excretion
of drugs;
3. Classify the
drugs that
act on the
nervous
system.
At the end of II. Diuretics Lecture Quiz
this chapter, the and Powerpoint Assignment
student should Cardiovasc presentation outputs
be able to: ular Drugs Assignment Prelim
1. Relate the (anatomy & exam
mechanis A. Diuretics physiology of
ms of and Drugs for Cardiovascular
action of the treatment of 6 System)
cardiovasc Hypertension ho
1. urs
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

ular drugs Physiology

and and control
diuretics of blood
to the pressure
physiolog 2.
y of the Pathophysi
cardiovasc ology and
ular and classificati
renal on of 4
systems; hypertensio ho
2. Categorize n, and urs
and goals in
differentia hypertensio
te drugs n therapy
that act on 3. Diuretics
the & other
cardiovasc classes of
ular Antihyperten
system; sive drugs
3. List a. Diuret
specific ics
drugs that b. Symp
are used in athopl
the egics 4
treatment c. Vasod ho
of ilators urs
cardiovasc d. Calciu
ular m
diseases; Chann
4. Rationaliz el
e the Block
effects of ers
drugs on e. Angio
the tensin
cardiovasc Modif
ular iers 4
system; ho
5. Present urs
and B. Mechanisms
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

rationalize of drugs used

a stepwise in the
approach management of
in the angina pectoris
treatment and other
of ischemic heart
hypertensi conditions
on. 1. Nitrovaso
dilators
2. Beta-
blockers
3. Calcium 2
channel ho
blockers urs

C.
Pharmacologic
approach to
heart failure
1. Pathophy
siology
classificat
ion and
approach
to therapy
of acute
and
chronic
congestiv
e heart
failure
2. Classifica
tion of
drugs
used for
HF
a. Inotro
pic
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

Agent
s
b. Pre-
load
and
afterlo
ad
unloa
ding
agents

D. Cardiac
rhythm and
drugs used for
arrhythmia

E.
Miscellaneous
agents
MIDTERM

At the end of III. Lecture Quiz

this chapter, the Respiratory Recitation, Assignment
student should Drugs assignment output
be able to: 4 (review of
A. Drugs used hou Respiratory
1. Distinguish for bronchial rs System anatomy
drugs based asthma and and physiology)
on their COPD
effect on 1. Pathophy
the siology of
respiratory COPD
system and and
their use; Bronchial
2. Rationalize Asthma
the use of 2. Pharmaco
certain logic
drugs for approach
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

specific to
respiratory bronchial
conditions; asthma &
3. Present and COPD
rationalize a a. Bronc
stepwise hodila
approach in tors
the b. Anti-
treatment of Infla
asthma mmat
ory

B. Cough and
mucus
production

At the end of IV. Lecture Quizzes

this chapter, the Gastrointestin
student should al Drugs
be able to: 6
A. hou
1. Classify Pharmacothera rs
gastrointesti py of Acid
nal drugs Peptic
according to Disorders
their 1. Antisecre
pharmacolo tory
gic action Agents
and a. H2-
therapeutic blockers
use; b. Proton-
2. Rationalize pump
the inhibitors
occurrence c.
of adverse Antimusc
effects arinic
associated agents
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

with the use 2. Cytoprote

of ctive
gastrointesti agents
nal drugs and
coating
agents
a. Protag
landin
analo
gues
b. Sucral
fate
3. Acid
neutralize
rs
4. Helicobac
ter pylori
eradicatio
n therapy
and
maintena
nce
therapy in
H. pylori-
associate
d acid
peptic
diseases

B. Drugs
affecting
gastrointestinal
motility and
secretion
1. Drugs for
the
managem
ent of
emesis
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

and
hypermot
ility
disorders
a. Metoc
lopro
mide
and
relate
d
comp
ounds
b. Seroto
nin
antag
onists
2. Pharmaco
therapy
of
diarrhea
a. Oral
Rehyd
ration
Thera
py
b. Opioi
ds and
relate
d
comp
ounds
c. Adsor
ptive
agents
3. Cathartic-
Laxatives
: Bulk,
Osmotic,
Saline,
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

Lubricant
At the end of V. Hormonal 3 Lecture Quiz
this chapter, the Agents hou Recitation Reaction
student should rs (review of paper
be able to: A. Physiology Endocrine Midterm
1. Differentiat of System) exam
e endocrine hypothalam Film viewing
hormones ic-pituitary (DM)
and control of
hormonal target
drugs based
on organ
therapeutic hormone
applications secretion
; B. Specific
Relate the hypothalamic
pharmacodynam and pituitary
ics and hormones
pharmacokinetic and
antagonists
s of hormonal
C. Gonadal
drugs to their
hormones
uses and and other
adverse effects reproductive
drugs
D.
Pharmacothe
rapy of
thyroid
disorders
E.
Adrenocortic
al hormones
F. Insulin and
drugs for
diabetes
mellitus
FINALS

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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

At the end of VI. Drugs for 6 Lecture Quiz

this chapter, the Metabolic and hou Recitation
student should Coagulative rs Written
be able to: Disorders report on
1. Differentiat (Hyperlipidemi blood
e the a, coagulati
various Osteoporosis, on
effects of Thrombosis, process
drug acting Bleeding)
on the
blood; A. Drugs for
2. Rationalize Hyperlipidemia
the choice B. Drugs for
of drugs for Coagulative
the Disorders:
treatment of Anti-
blood Thrombotics,
disorders Procoagulant
s
C. Vitamin D
and
Bisphosphon
ates
At the end of VII. Drugs 4 Lecture Quiz
this chapter, the that Modify hou Recitation Recitation
student should Immune rs (review of
be able to: Function Organic
1. Present and (Allergy, Medicinal
rationalize a Rheumatoid Chemistry)
stepwise Arthritis and
approach in Vasculitides,
the Nephritic
treatment of Syndrome,
rheumatoid Immunosuppre
arthritis; ssion Therapy)
2. Relate the A. DMARDs
action of drugs B.
that modify Immunosuppre
ssive Agents:
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

immune Glucocorticoste
function to the roids,
physiology of Cyclosporine,
the immune Interferon,
system Cytotoxic
Agents
At the end of VIII. 6 Lecture Quiz
this chapter, the Chemotherape hou Recitation Reaction
student should utic Agents rs (review of paper
be able to: Organic Final exam
A. Antibacteri Medicinal
1. Differenti al Chemistry)
ate B. Antifungal Film viewing
diseases C. Antiviral (cancer)
that D. Antiprotoz
require oal
chemothe E. Anthelmint
rapeutic ic
agents for F. Cancer
treatment; Chemotherape
2. Rationali utic Agents
ze drugs
of choice;
3. Explain
the
occurrenc
e of
adverse
effects
associate
d with the
use of
chemothe
rapeutic
agents
Explicate the
importance of
compliance to
antibiotic
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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

dosage regimen.

13. Learning Resources:

A. Main Reference/s
Katzung, Bertram G. (2003). Basic and Clinical Pharmacology 10th ed. USA: Appleton and Lange;
Trevor, Anthony, Bertram G. Katzung and Susan B. Masters, editors.(2003). Katzung and Trevor’s Pharmacology 7th ed. USA: McGraw-Hill.

B. Books

Craig, Charles R. and Robert E. Sitzel, ed. (2004). Modern Pharmacology with Clinical Applications. Philadelphia: Lippincott Williams and
Wilkins.
Hardman, Joel G., Lee E. Limbird and Alfred Gilman, editors (2003). Goodman and Gilman’s Pharmacological Basis of Therapeutics 10th ed.
USA: McGraw-Hill.
Hitner, Henry and Barbara Nagle (1994). Basic Pharmacology for Health Occupation 3rd ed. USA: MacMillan/McGraw-Hill.
McPhee, Stephen J. and William F. Ganong (2006). Pathophysiology of Disease: An Introduction to Clinical Medicine 5 th ed. New York: The
McGraw-Hill Companies.
Rang, H.P. et al. (1999). Pharmacology 4th ed. London: Churchill Livingstone.
Tortora, Gerard J., Berdell R. Fluke and Christine L. Case (2004). Microbiology: An Introduction 6th ed. San Francisco: Pearson Education, Inc.

14. Final Course Requirement

Course Learning Outcomes Required Output Due Date

15. Assessment and Grading System

PRELIM GRADE MIDTERM GRADE TEMPORARY FINAL GRADE FINAL GRADE

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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

16. Course References

A. Main Reference/s
Katzung, Bertram G. (2003). Basic and Clinical Pharmacology 10th ed. USA: Appleton and Lange;
Trevor, Anthony, Bertram G. Katzung and Susan B. Masters, editors.(2003). Katzung and Trevor’s Pharmacology 7th ed. USA: McGraw-Hill.

B. Journals

C. Books
Craig, Charles R. and Robert E. Sitzel, ed. (2004). Modern Pharmacology with Clinical Applications. Philadelphia: Lippincott Williams and
Wilkins.
Hardman, Joel G., Lee E. Limbird and Alfred Gilman, editors (2003). Goodman and Gilman’s Pharmacological Basis of Therapeutics 10th ed.
USA: McGraw-Hill.
Hitner, Henry and Barbara Nagle (1994). Basic Pharmacology for Health Occupation 3rd ed. USA: MacMillan/McGraw-Hill.
McPhee, Stephen J. and William F. Ganong (2006). Pathophysiology of Disease: An Introduction to Clinical Medicine 5 th ed. New York: The
McGraw-Hill Companies.
Rang, H.P. et al. (1999). Pharmacology 4th ed. London: Churchill Livingstone.
Tortora, Gerard J., Berdell R. Fluke and Christine L. Case (2004). Microbiology: An Introduction 6th ed. San Francisco: Pearson Education, Inc.

D. Electronic References

Revised and Updated: Date:

Prepared by Reviewed by Approved by

Rhoda S. Lumang-ay, RPh, MSPharm Ann P. Opiña, RMT, MMHSM

Faculty Department Head Dean

Fortune L. Torrecampo, RMT, MPH

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 Saint Louis University
SCHOOL OF NATURAL SCIENCES
Department of PHARMACY

School-based QA Officer

Annexes:
A. Alignment Matrix
B. Assessment tools/rubrics
C. Table of Specifications per term

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