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Shimadzu FTIR 8400s Manual

The document describes the Shimadzu FTIR-8400S Fourier transform infrared spectrophotometer. It has a maximum resolution of 0.85 cm-1 and achieves an excellent signal-to-noise ratio of 20,000:1 or better. The instrument uses dynamic alignment to ensure optimal alignment and reproducible spectra. It can interface with a variety of sampling accessories and options for microscopy and automation.

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Mohammed Hamzah
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0% found this document useful (0 votes)
803 views16 pages

Shimadzu FTIR 8400s Manual

The document describes the Shimadzu FTIR-8400S Fourier transform infrared spectrophotometer. It has a maximum resolution of 0.85 cm-1 and achieves an excellent signal-to-noise ratio of 20,000:1 or better. The instrument uses dynamic alignment to ensure optimal alignment and reproducible spectra. It can interface with a variety of sampling accessories and options for microscopy and automation.

Uploaded by

Mohammed Hamzah
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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C103-E063F

FTIR-8400S

Shimadzu
F o u r i e r Tra n s f o r m
I n f r a re d S p e c t ro p h o t o m e t e r
Discover the Advantages of the FTIR-8400S
FTIR-8400S
S h i m a d z u Fo u r i e r Tra n s fo r m I n f ra r e d S p e c t r o p h o t o m e t e r

D i s c ove r t h e A d va n t a g e s o f t h e F T I R - 8 4 0 0 S

Shimadzu was the first company to offer dynamic alignment as a standard feature in an
affordable FTIR spectrometer. With state-of-the-art technology, the Shimadzu dynamic alignment
system continuously maintains optimal alignment during data acquisition, ensuring consistently
reproducible spectra without the need for tedious mechanical adjustments.
FTIR-8400S is combined with the IRsolution - a 32 bit high performance FTIR software - to
analyze your samples easily and securely.

The Dynamic Alignment Advantage The IRsolution Advantage


Optimal interferometer alignment is maintained automatically Powerful IRsolution software offers a myriad of standard data
for continuous optimization and exceptional reproducibility. processing functionsThe management of User group,
protection by user name/password, Operrecording, and
Electric Signature supports the FDA 21 CFR Part 11. note)
The Signal-to-Noise Advantage
Peak-to-Peak S/N ratio is 20,000:1 or better, guaranteed!
The Validation Advantage
The software validates instrument performance to ensure
The Simplicity Advantage compliance based on Japanese/European Pharmacopoeia and
New FTIR operators will love the quick-start function that ASTM. The instrument and data reliability are ensured by
prompts the user through every action from setting scan GLP/GMP and FDA 21 CFR Part 11 compliance.
parameters and acquiring the spectrum, to detecting peaks
and printing.
note) IRsolution Agent software is needed to fully comply to FDA 21 CFR Part 11 regulation.

Contents P 04 - Hardware Features P 10 - Software P 13 - Hardware Reliability

P 06 - Versatility P 12 - Validation Reliability P 14 - Optional Software


H a rdw a r e F e a t u r e s

FTIR-8400S
[M a x i m u m r e s o l u t i o n o f 0 . 8 5 c m - 1 . E x c e l l e n t s i g n a l - t o - n o i s e o f 2 0 , 0 0 0 : 1 o r b e t t e r .]

With a maximum resolution of 0.85cm-1, the FTIR-


8400S achieves the best signal-to-noise ratio in its
price-class by 20,000:1 or better (peak-to-peak,
4cm-1 resolution, averaged over 1 minute). Designed
with the user in mind, this instrument can be
operated using an ordinary desktop or a laptop PC.

0.85cm-1 maximum resolution


20,000:1 or better peak-to-peak S/N ratio
Dynamic alignment ensures optimum performance
On-screen instructions for easy operation
Laptop PC control is available.

D y n a m i c a l i g n m e n t e n s u r e s r e p ro d u c i b i l i t y by m a i n t a i n i n g o p t i mu m a l i g n m e n t

Highly precise control of the moving mirror is required to


stabilize the interferogram of the FTIR instrument. The Piezo-actuator
FTIR-8400S includes the patented FJS system - very DSP
smooth and precise moving mirror unit - and the Dynamic He
-Ne Signal amplifier
Alignment system to optimize and stabilize the inter- las
er
ferometer unit. FTIR-8400S requires only a short
Fixed mirror
stabilization time and is very secure.
Electromagnetic drive Infrared beam
(patented)
Dynamic Alignment (Patented)
Moving Beam splitter
This System monitors the interferometer condition of He- mirror Laser
Polarized Detector B
Ne laser and compares it with that of optimized beam splitter (signal)
conditions.
Any detected discrepancies by DSP system are Laser Detector A
(interference pattern)
corrected by automatic alignment of the piezo actuators To sample
at the fixed mirror. compartment Feedback
circuit for
dynamic
auto-alignment

4
Ve rs ati l i ty

Versatility 1
[Interface with a wide variety of sampling accesories. Microscopy and automation options are available.]

Match the versatile FTIR-8400S with automation and microscopy options, as well as a wide variety of Shimadzu
and other commercially available accessories, to easily accommodate a myriad of sample types.

FTIR Microscopy System featuring the Shimadzu AIM-8800

Perform high-precision analysis of micro-


samples as small as 10μm quickly and easily
with this fully automated FTIR microscope
system, equipped with a high sensitivity MCT
detector. The standard features include auto
aperture, auto focusing, auto X-Y-Z stage
movement and auto centering, as well as the
transmittance and reflectance modes, and the
on-board video-camera. Meet all your sampling
requirements with such convenient options as
grazing angle objectives, various ATR
objectives and mapping software.

Universal sampling with a diamond ATR

Left Side : System I (High Pressure Device type) Infrared spectrum of diphenhydramin hydrochloride(powder sample)
Right Side : System H(ViewIR type)
measured with DuraSampllR2A (ATR-corrected spectrum)
The DuraSampllR2A has two types of diamond prism, a diamond
prism supported by a ZnSe lens and a diamond prism supported
by a KRS-5 lens. The ZnSe type can measure up to around
600cm-1. On the other hand, the KRS-5 type can measure up to
around 400cm-1. The infrared spectrum of diphenhydramin
hydrochloride measured with the diamond prism supported by a
KRS-5 lens is shown above. The KRS-5 type can give the infrared
spectrum without noise up to 400cm-1. Plastics, rubbers, files and
liquid samples can be measured with the DuraSampllR2A.

5
Ve rs ati l i ty

Versatility 2
For Liquid samples
For measuring liquid samples, demountable or AT R - 8 2 0 0 H A (P/N 208-97240-91)
sealed liquid cells may be used. Additionally, the
A liquid sample trough plate and a solids flat
ATR (Attenuated Total Reflectance) accessories
plate prisms are available to conveniently
are also convenient.
accommodate a range of liquid, solid and film
To measure liquids with ATR, sample preparation
samples. The ZnSe prism is standard in most
is as simple as dispensing the liquid onto the
accessories. A Ge prisms is available for high
prism of the accessory. The ATR correction
refractive index samples such as black
program in the IRsolution software converts the
rubber.Both the ZnSe prism and the Ge prism
measured ATR spectrum into a normal
are water resistant, so even aqueous solutions
transmittance measurement by correcting for
can be easily and conveniently measured.
depth penetration differences.

M I R a cl e A ZnSe : P/N 208-97247-95


( Ge : P/N 208-97247-96 )
Single bounce ATR with a 2mm diameter prism.
This accessory is suitable for liquid, solids,
powders, films, and a variety of other sample
types. The ZnSe prism is standard.
A Ge prism is available for high refractive index
samples.

F o r p ow d e r s a m p l e s
For measuring powder samples, conventional D R S - 8 0 0 0 A (P/N 206-62301-91)
KBr pellet methods may be used. The Diffuse
Sample is mixed with KBr powder, placed in a
reflectance method is also convenient and
sample cup and measured.With the Kubelka-
requires less sample preparation. In the Diffuse
Munk conversion in the IRsolution software, the
reflectance method, the sample is mixed with
diffuse reflected spectra can be converted into
KBr powder and then measured, there is no
transmission spectra for comparison purposes.
need for making a pellet. Single Bounce ATR
accessories may also be used for powder
samples in some cases.

For gases
Various gas cells are available for gas sample
measurement. The path length is selected
according to concentration of the gas. Various
path length cells are available ranging from 5cm
to 20m.

5cm gas cell P/N202-32006-30(KRS-5 window)


10cm gas cell P/N202-32007-30(KRS-5 window)

5cm gas cell 10m gas cell

6
For solid samples, films, cast resins
The transmission method is effective for film AT R - 8 0 0 0 A (P/N 206-62303-91)
samples up to 100μm thick. For films thicker
This accessory can measure film samples
than 100μm, multi layer film and cast resins, ATR
clamped firmly on one or both sides of the prism.
(Attenuated Total Reflectance) is recommended.
A large contact area results in good sensitivity.
Samples are clamped to the prism to ensure
The KRS-5 prism is standard, a Ge prism is also
contact. With the ATR method, a spectrum is
available for samples with a high refractive
taken through a depth of a few μm within the
index.The incident angle on the sample is
sample. For samples with high refractive indices,
switchable between 30/45/60°, allowing for
the Ge prism is suitable. For hard samples, the
accumulation of spectra at different depths.
diamond prism is preferred. With the ATR
correction available within the IRsolution
AT R - 8 2 0 0 H A (P/N 208-97240-91)
software, ATR spectra is converted into a normal
transmittance spectra. Another method for these A liquid sample trough and a solids flat plat prism are available
sample types, involves scratching the surface of to conveniently accommodate a range of liquid, solid and film
the sample and measuring with a diffuse samples. The ZnSe prism is standard in most accessories.
reflectance accessory. A Ge prisms is available for high refractive index samples.
The measuring light is reflected through the prism 10 times.
The sample is clamped firmly to the prism to ensure contact
with an attached clamp and easily adjustable clamp pressure.

M I R a cl e A ( ZnSe : P/N 208-97247-95


Ge : P/N 208-97247-96 )
Single bounce ATR with a 2mm diameter prism.
This accessory is suitable for liquid, solids,
powders, films, and a variety of other sample
types. The ZnSe prism is standard.
A Ge prism is available for high refractive index
samples. The sample can be easily clamped to
prism with the attached clamp with adjustable
pressure. For hard samples, the Diamond
MIRacle with diamond prism is available.

DuraSampllR2A System I DuraSampllR2A System I DuraSampllR2A System H


(With Pressure Sensor)
ZnSe support:P/N 208-92143-11 ZnSe support:P/N 208-92144-11
( KRS-5 support:P/N 208-92143-12 )(KRS-5 support:P/N 208-92144-12 ) ( ZnSe support:P/N 208-92145-11
KRS-5 support:P/N 208-92145-12 )
Single Bounce ATR with a 2mm diameter
diamond prism. This accessory is good for
measuring hard samples that may damage other
prism types. It is also suitable for liquid, solids,
powders, films, and a variety of other sample
types. The System I (High Pressure Device Type)
allows the sample to contact the prism easily
with the attached clamp and adjustable pressure.
The System H (ViewIR Type) allows the sample
to be visually observed while clamping.

S i C S a m p l e r (P/N 200-66750)
This sample preparation accessory has SiC
emery paper that is used to scratch the sample
of interest. The powder of the sample on the
emery paper is directly analyzed with a Diffuse
Reflectance Accessory.

7
Ve rs ati l i ty

Versatility 2
For coating films on metals or resins
For coatings, Reflectance is the measurement S R M - 8 0 0 0 A (P/N 206-62304-91)
method is a choice. Selection of Specular
Specular Reflectance accessory with 10°
Reflection or Reflection absorption method is
reflection. Samples are placed on the top of the
dependent on the thickness of the coating
accessory with the measurement side down.
sample.
Analysis of μm thick thin films is possible.
The specular reflectance spectra can convert
into a transmittance spectra with Kramers-Kronig
conversion in the IRsolution software.

R A S - 8 0 0 0 A (P/N 206-62302-91)
Reflection absorption spectroscopy method
accessory with 70° or 75° reflection angle. Analysis of
nm thick thin films is possible. The optional GPR-8000
polarizer allows for higher sensitivity measurement.
When a polarized light beam is incident on a metal
substrate, the phase of the light is changed. In
vertical polarization, the vectors of the polarized
light are opposite to each other, and hence no
stationary waves are produced . In parallel
polarization, the the vectors of the polarized light
meet at the point to produce stationary waves,
which enhances the sensitivity of the measurement.

A c c e s s o r y fo r a u t o m a t e d a n a ly s i s
Various automation accessories, are available to A S C - 8 0 0 0 T (P/N 206-63900)
provide efficient analysis of large numbers of
ASC-8000T is an auto sample changer for
samples.
performing transmission measurements on up to
18 samples. The holder is designed for 13mm
diameter KBr pellets and optional film-holder or
cell plates for Nujol mulls are also available.
The ASC-8000T can be easily controlled by the
IRsolution software.

Applications

D R S - 8 0 1 0 A S C (P/N 206-62308)
DRS-8010ASC are automatic diffuse reflectance
accessories. The DRS-8010ASC accepts up to
24 samples. The DRS-8010ASC can be easily
controlled by IRsolution software.

Infrared spectrum of lactose


Infrared spectrum of lactose measured with the
DRS-8010ASC automatic diffuse reflectance
accessory (Kubelka-Munk concerted spectrum)

8
Versatility 3
Space Efficient Laptop PC Control
A unique laptop PC rack option (note1) reduces the
system footprint to just 630mm (W) by 592mm (D),
and the height to only 530mm. Process your data
anywhere with this portable PC option.

(note1) Rack accommodates 13.3 inch laptop PC.


(note2) Microscope-equipped systems require desktop PC.
(note3) Special SCSI interface for laptop PCs is required.

Easy Operation
The simplicity of the software makes it perfect for routine work within QA/QC departments or educational
institutions, the main procedure is to operate some limit number of functions. In either case, procedures can be
simplified by standard Easy-Scan program, all procedures including the setting of measurement parameters,
analysis of the sample, data processing, saving, and printing the results are performed with one click operation.

The IRsolution software is equipped with an Easy-Scan


program. This macro program takes the user step by step
through the entire analysis from spectrum measurement,
peak detection, printout and saving of the result data.
On screen instructions guide the operator ever step of
the way. This feature allows for a decrease in the learning
curve for operating the IRsolution
and the FTIR-8400S.

Scan Parameter Setting

BKG Measurement

Peak Detection

9
Software

IRsolution
IRsolution software provides windows based 32bit software control for the FTIR-8400S. With IRsolution, operations
for FTIR analysis can be performed easily and quickly using dedicated analysis screens
Spectrum measurement
Data display and comparison to other spectra
Data processing, quantitation and spectral searching
Report Generation
As the operation progresses, the IRsolution software automatically advances into the optimum mode. Optional
software such as PLS quantitation modules are available for increased versatility.
You can quickly access the many useful functions of IRsolution by customizing the User Interface of software.

Measurement and Status Monitor


In the measurement menu of IRsolution, all
measurement start buttons and dialogs to set the
analysis parameters are integrated for easy operation.
All measurement parameters are arranged into four
dialog screens that are easily viewed.
One click operation will start the analysis. During
measurement, a real time spectrum is displayed on
screen.
The hardware settings are displayed on the status
monitor screen.

Status Monitor

View Mode
After the data is acquired, you can use the View Mode to
zoom in on certain areas or compare with other spectra.

10
Data Manipulation, Quantitation and Spectrum Search
After the data acquisition has been completed, you can extract
a variety of specific information from measured spectrum.
The IRsolution software has many functions ranging from Peak
detection, spectral subtraction, Kubelka-Munk conversion and
ATR correction functions to optional Spectrum searching and
Quantitation. The results of data processing can be imported
into Word Processing and Spread
Sheet software applications.

Pesk Picking
Spectrum Search

Quantitation

Quantitation
In addition to multi-point calibration curve methods, the IRsolution
software offers MLR (Multi Linear Regression) and optional PLS
(Partial Least Squares) analysis that is useful for NIR measurements.
Spectrum Search
The IRsolution software allows the creation of user libraries from
acquired spectra, and spectral searching of user and commercial
libraries.

Report Generator
Data is not useful unless you can get the
results in the desired format.
The IRsolution software includes a powerful
report generator with customized layout
features. With the Report Generator, you can
create reusable print templates using any
data including the spectrum, calibration
curve, quantitation results and peak pick
tables. You can set the thickness and color of
the graph lines as well as the font size.
Annotations may be attached on the graph to
comment on the results.
The print layout can be saved as a template
file for later use, ensuring accurate repeat
reporting.

11
Va lid ati on Re l i a b i l i t y

Reliability 1
FTIR-8400S has many features on hardware and within the software that improve reliability. Measurement
conditions of the FTIR-8400S are constantly monitored and may be reported at anytime.
IRsolution is complied to GLP and FDA 21 CFR Part 11. note1)

Validation Program and Report


FTIR-8400S comes standard with a validation program that complies with
Japanese/European Pharmacopoeia and ASTM (American Society of Testing
and Materials).
This validation program checks the performance of the FTIR-8400S using a
polystyrene film and creates a report upon completion.

Test Items for Japanese/European Pharmacopoeia


Shape and Intensity of Power spectrum
Measurement of Polystyrene film spectrum
Resolution
Wavenumber accuracy
Wavenumber Reproducibility
Transmittance Reproducibility
Test Items for ASTM (ASTM1421 Level Zero)
Energy Test by Power spectrum
100%T Line Test
Polystyrene Film Test

Compliant with GLP/GMP and FDA 21 CFR Part 11


Recently, the reliability and security of the software controlling the instrument and the collected data have become more important. The FDA
regulations such as 21 CFR Part 11 in the Pharmaceutical market and GLP/GMP in the food industry are examples. The FTIR-8400S with the
IRsolution and IRsolution Agent software includes the following features and supports GLP/GMP, ISO-9000 series and FDA 21 CFR Part 11.
Security and log function with User name/Password
Restriction of user rights by user group
Raw data preservation including interferogram and background spectrum before FFT.
History log of data processing.
Electronic signature note2)
Instrument and software installation according to IQ/OQ documentation is available.

Software security by User name and Password


By requiring a user name and password upon startup of the IRsolution software, security can
enhanced by restricting the functions or methods for the particular user within a user group.
An administrator can restrict the functionality that is available within IRsolution to each particular
user and can control all the user rights.
The logon information is recorded into a log-file with the date, time and user name.

Data Preservation, Operation Logging, Audit-trail of the instrument


Spectra that are obtained by the IRsolution software are stored in a Container file that includes
with scan parameters, background and the original interferogram.
When a data manipulation is performed, the processed data is added to the file along with date
Electronic signature
and time of processing, user name and the manipulation method. The original data is preserved - in IRsolution
not overwritten. All instrument related information including the power on date/time, user name,
results of the instrument initialization, date/time of measurement, and attached accessories are
recorded as an audit-trail.
This file can be displayed and is write-protected by the IRsolution software for security.
The electronic signature is also supported for FDA 21 CFR Part 11 compliance.note2)

note1) IRsolution Agent software is needed to fully comply to FDA 21 CFR Part 11 regulation.
note2) The electronic signature should be done by IRsolution Agent software for FDA 21 CFR Part 11. Operation Log

12
H a rdw a r e R e l i a b i l i t y

Reliability 2
The Interferometer is one of the most important parts of the FTIR. For accurate data collection, the interferometer
must scan with high precision. The FTIR-8400S includes the Patented FJS system which scans the moving mirror
with a smooth and stable mechanism. The optimization and stabilization of the FTIR-8400S interferometer by
Dynamic Alignment system ensures consistent and repeatable results. Since the beam splitter within the
interferometer is susceptible to moisture, the optical system of the FTIR-8400S is sealed and desiccated.

Protection of the Interferometer and Atmosphere Correction


The Interferometer is one of the most important parts of the FTIR.
The FTIR-8400S has 3 features to stabilize the interferometer and to protect the beam splitter.
1. Sealed optical system to create closed environment
2. Anti Humidity Beam Splitter coating to provide extra protection
3. Desiccated interferometer to remove moisture by Desiccants

The Atmosphere Correction Function easily


compensates for the influences of water vapor and
He-N
e las
carbon dioxide on your data. You can easily get
er Colimator
Fixed mirror mirror beautiful spectra with the FTIR-8400S even if the
sample has peaks which are overlap with water vapor
Light
BS sourse around 2100-1300cm-1 or 4000-3100cm-1.
Moving mirror

Laser detector

Sealing case

Sample KRS-5 window


position
Condensing mirror

Detector Elimination of influences of CO2 and H2O by Atmosphere Correction

Blue : Spectrum Before Atmosphere Correction Red : Spectrum After Atmosphere Correction

13
Optional Software

Optional Software
Wide varieties of optional software to enhance IRsolution capabilities
Powerful 32-bit Windows based software - IRsolution - has various optional software modules to enhance its performance:
IRsolution Agent
Mapping software - AIM-MAP (for the AIM-8800 Microscope)
PLS quantitation software
Curvefitting (Peak split) software
PharmaReport Program note)
Macro Platform
IRsolution includes a wide selection of data manipulation operations which include:
spectral subtraction and Kubelka-Munk conversion; Variety of Quantitation operations - Multi-point Method and Multiple Linear Regression
(MLR) method; as well as Spectral search functions. The optional software for IRsolution expands the application capabilities of IRPrestige-21.
note) In order to use PharmaReport Program, the separately available Macro Platform is required.

I R s o l u t i o n A g e n t (P/N 206-21600-92)
IRsolution Agent software is an Add-On software module for
IRsolution to meet FDA 21 CFR Part 11 regulations and/or to
manage obtained data. IRsolution Agent software consists of a
database function and a data registration function from
IRsolution to IRsolution Agent, as well as electronic signature
capabilities.

CLASS-Agent screen and data registered in CLASS-Agent database

M a p p i n g P ro g r a m A I M - M A P (P/N 206-72332-91)
Mapping Software - AIM-MAP - captures visual images from
the AIM-8800 microscope and creates a large composite
visual image of your sample. Mapping conditions such as
Mapping area, Scan intervals, Background position and etc.
are set up on the composite image. You can operate the AIM-
8800 microscope and AIM-MAP through simple point and click
operations. AIM-MAP has 3 types of mapping modes - Area
mapping, Line mapping and Random mapping. Not only can
traditional transmittance/reflectance measurements be done,
but also micro-ATR mapping with an optional ATR objective
are available. IRsolution mapping has various data
manipulation functions such as extracting a spectrum from
mapped data or reprocessing functional-group mapping.
The mapped data can be shown as 3D bird's-eye view,
counter plot or spectral overlay mode.

Area mapping data


Mapped data of flux on a circuit board

14
PLS Quantitation Software (P/N 206-72331-91)
PLS (Partial Least Squares) quantitation is a widely used
Chemometrics method like Multiple Linear Regression (MLR) method
for quantitation of multicomponents.
IRsolution has PLS I and PLS II method for PLS quantitation. IRsolution
analyzes PLS calibration curves by calculating "Influence", "Residuals",
"Scores", "Loadings", "Press Values", etc.

Screen of PLS quantitation

Curve fitting (Peak split) Software (P/N 206-72333-91)


Usually, an IR band can consist of several overlapping peaks. Curve
fitting (Peak split) software separates IR bands to individual component
peaks. This software is good for many applications such as analysis of
peak with hydrogen bond influences, and analysis of hidden peaks
overlapped with other peaks. Curve fitting (Peak split) software
separates the band with suitable curves from 6 types of curve such as
Gaussian, Lorentian, Gaussian+Lorentian. Component peaks and a
synthesized peak are displayed to evaluate the separation.

Curve fitting (Peak split) result of peak (3150-2750cm-1) of ABS resin spectrum.
Top : Target peak and specified peaks
Bottom : Component peaks and a synthesized peak

PharmaRepor t Program note) (P/N 206-72365-91)


This optional program compares the measured spectra of test samples with the
spectra of reference samples previously measured and registered to generate
Pass/Fail reports based on the identification test in the pharmacopoeias.
The program conducts the following calculations and comparisons:
Calculates the discrepancy in the peak wavenumbers of the sample
being checked and the reference previously registered.
Calculates the peak intensity ratio at several designated evaluation
peaks for comparison between the sample and reference.
The result is evaluated as "Pass" if both the wavenumber
discrepancy and peak intensity ratio fall within the permissible range.
In addition to the functions above, it is also possible to detect and print the
previously designated peaks only, and to print out the spectra of the measured
sample and the reference side by side.
note) In order to use this program, the separately available Macro Platform (P/N:206-72330-91) is required.

M a c ro P l a t fo r m (P/N 206-72330-91)
Macro Platform is a module to run Macro programs provided by Shimadzu on IRsolution software. Please contact your Shimadzu
representatives when you need an automatic measurement system with an automatic sample changer or to do routine operation with repeated
specified operations.

15
Specifications Dimensions
Interferometer Michelson type with 30° incident angle, dynamic
With desktop PC (Unit : mm)
alignment, sealed and desiccated
Optical system Single beam optics 305
Beam splitter Germanium-coated KBr plate
Light source High brightness ceramic

326

584
Detector Temperature controlled high sensitivity detector
(DLATGS detector)
S/N ratio Greater than 20,000:1 (KRS-5 window, 4cm -1 ,
1 minute, 2200cm-1, P-P)
Wavenumber range 7,800cm -1 - 350cm -1 622
460
Resolution 0.85, 1, 2, 4, 8, 16cm -1
Mirror speed 3 steps; 2.8, 5, 9mm/sec
Data sampling He-Ne laser
Sample compartment W200mm x D230mm x H170mm

250
Data processing Arithmetic operation between spectrum and constant,
functions Arithmetic operation among spectra, Spectral subtraction,
Peak detection, Smoothing, Derivative, Baseline correction,
Data correction, Normalization, Kubelka-Munk conversion,
Kramers-Kronig analysis, ATR correction
Optional programs IRsolution Agent, PLS quantitation, Curve fitting, With laptop PC using rack (Unit : mm)
Mapping, Macro platform, PharmaReport Program
Validation programs Compliance to Japanese/European Pharmacopoeia 630
and ASTM 320
GLP/GMP Operation log recording, Software protection by
user name/password, Management of user level

260
FDA 21 CFR Part 11 (note1) Electronic signature, Data manipulation history

592
recording, Saving of measured interferogram/
background spectrum/manipulated spectra
Ambient conditions 15 - 30°C
Less than 70%
Power requirement AC100/120/220/230/240V 50/60Hz 160VA (note2)
(note1) IRsolution Agent software is needed to fully comply to FDA 21 CFR part 11.
(note2) PC requires additional power.
530
PC Specifications 260

Type Desktop (SCSI interface for desktop PC is required.)


Notebook (SCSI interface for notebook PC is required.)
OS Microsoft Windows 2000 (note3)
CPU Celeron 766MHz or Duron 850MHz or Pentium3 850MHz and later (note4)
Video 1024 x 768 pixels/256 color or better (note5) Dimensions for PC and Printer depend on models.
RAM 128MB and more
HDD 30MB and more for free space
(note3) Windows is a trademark of Microsoft Corporation.
(note4) Celeron and Pentium are trademarks of Intel Corporation, Duron is trademark
of Advanced Micro Devices, Inc.

JQA-0376

Founded in 1875, Shimadzu Corporation, a leader in the


development of advanced technologies, has a distinguished
history of innovation built on the foundation of contributing to
society through science and technology. We maintain a global
network of sales, service, technical support and applications
centers on six continents, and have established long-term
relationships with a host of highly trained distributors located
in over 100 countries. For information about Shimadzu, and to
contact your local office, please visit our Web site at
www.shimadzu.com

SHIMADZU CORPORATION. International Marketing Division


3. Kanda-Nishikicho 1-chome, Chiyoda-ku, Tokyo 101-8448, Japan
Phone: 81(3)3219-5641 Fax. 81(3)3219-5710
URL http://www.shimadzu.com
The contents of this brochure are subject to change without notice.

Printed in Japan 3295-09611-30ATD

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