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Laboratory Activity 2: Tertiary Drug Information Resources: A. Easy (10 PTS) Question/Topic Answer

The document provides instructions for a laboratory activity involving research of tertiary drug information resources. Students are assigned three questions of varying difficulty to research and answer. They must note the reference used to find the answer and submit their responses before 11:00 AM. The questions include the normal fasting plasma glucose level, the weight of active ingredient that warrants content uniformity testing for tablets, and the reason why people with blood type AB are considered universal recipients.

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Aria Domingo
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155 views3 pages

Laboratory Activity 2: Tertiary Drug Information Resources: A. Easy (10 PTS) Question/Topic Answer

The document provides instructions for a laboratory activity involving research of tertiary drug information resources. Students are assigned three questions of varying difficulty to research and answer. They must note the reference used to find the answer and submit their responses before 11:00 AM. The questions include the normal fasting plasma glucose level, the weight of active ingredient that warrants content uniformity testing for tablets, and the reason why people with blood type AB are considered universal recipients.

Uploaded by

Aria Domingo
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Laboratory Activity 2: Tertiary Drug Information Resources

Pharmacy Informatics Lab

Names: ___________________________________________________ Section: ________

General Instructions

1. Below are specific questions which you are asked to research on.
2. Note which particular tertiary reference you consult by writing the bibliographic entry using Harvard
System.
3. Answer the question accurately and briefly
4. Submit the data sheet before 11:00 AM (speed 5 pts)

A. Easy (10 pts)

QUESTION/TOPIC ANSWER
What is the normal fasting plasma glucose level
(FPG)?

REFERENCES:

B. Average (15 pts)

QUESTION/TOPIC ANSWER
What weight of active ingredient warrants
content uniformity test for tablets?

REFERENCES:

C. Difficult (20 pts)

QUESTION/TOPIC ANSWER
What is the reason why people with blood type
AB are considered as the universal recipients?

REFERENCES:
Laboratory Activity 2: Tertiary Drug Information Resources

Pharmacy Informatics Lab

Names: ___________________________________________________ Section: ________

General Instructions

1. Below are specific questions which you are asked to research on.
2. Note which particular tertiary reference you consult by writing the bibliographic entry using Harvard
System.
3. Answer the question accurately and briefly
4. Submit the data sheet before 11:00 AM (speed 5 pts)

A. Easy (10 pts)

QUESTION/TOPIC ANSWER
What is the operation The paddle method is very sensitive to tilting. Improper alignment may
speed for paddle in drastically affect the dissolution results with some drug products. The most
dissolution apparatus? common operating speed for solid oral dosage form is 2-50 rpm and 25 rpm
for suspensions.
REFERENCES: Phaldesai, S., 2013. Dissolution Apparatus. September, p. 8. Available at
https://laney.edu/cheli-fossum/wp-content/uploads/sites/210/2012/01/9-
Amino-Acids-and-Proteins.pdf (Acessed 26 January 2021)

Gray, V.A., Brown, C.K., Dressman, J.B. and Leeson, J. 2001. A New General
Information Chapter on Dissolution. Pharmacopeial Forum 27(6):3432-3439
(Acessed 26 January 2021)

USP Pharmacopeia Available at:


https://www.usp.org/sites/default/files/usp/document/harmonization/gen-
method/q01_pf_ira_32_2_2006.pdf (Acessed 26 January 2021)

B. Average (15 pts)

QUESTION/TOPIC ANSWER
Which of the following Amino Group- Biuret Test
test is specific for Free Amino Group- Ninhydrin Test
amino acids and free
amino group: Biuret
test, Hopkin’s cole
test, Ninhydrin test, or
Xanthoproteic test?

REFERENCES: Charlwood, B. & Bell, E., 1977. Qualitative and quantitative analysis of
common and uncommon amino acids in plant extracts,. Journal of
Chromatography A, Volume 135(Issue 2), pp. Pages 377-384. Available at
https://www.sciencedirect.com/science/article/abs/pii/S0021967300883788
(Acessed 26 January 2021)

C. Difficult (20 pts)


Laboratory Activity 2: Tertiary Drug Information Resources

QUESTION/TOPIC ANSWER
This anti-infammatory drug for rheumatoid The primary adverse effects of prednisone include
arthritis should only be administerd for a brief hyperglycemia, insomnia, increased appetite,
period due to serious adverse effects such as hypertension, osteoporosis, edema, adrenal
osteoporosis, cataract formation, and impaired suppression, cataracts, and delayed wound
wound healing on long term use. Which of the healing.
following is it likely to be: aspirin, prednisone or
sulfazalazine? Adverse effects are common in patients receiving
glucocorticoids in high doses or over a long
period. Potential adverse effects include skin
fragility, weight gain, increased risk of infections,
and fractures. Significant cardiovascular and
metabolic effects are hypertension,
hyperglycemia, and dyslipidemia
REFERENCES: Bergmann TK, Barraclough KA, Lee KJ, Staatz CE.
Clinical pharmacokinetics and
pharmacodynamics of prednisolone and
prednisone in solid organ transplantation. Clin
Pharmacokinet. 2012 Nov;51(11):711-41

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