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L T P C 2 1 0 Course Code: CHE108 Semester: III Bioprocess Calculations Course Objective

This document outlines a course on bioprocess calculations. The course has 4 units that cover material and energy balance calculations, as well as their applications to chemical and biochemical processes. Unit 1 covers gas laws and composition calculations. Unit 2 applies material balancing to unit operations. Unit 3 covers material balancing of chemical reactions and calculating stoichiometric coefficients. Unit 4 performs energy balancing of reactive and non-reactive processes. The course aims to provide students with skills in various process calculations.

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ARUN K CHOCKALINGAM
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65 views2 pages

L T P C 2 1 0 Course Code: CHE108 Semester: III Bioprocess Calculations Course Objective

This document outlines a course on bioprocess calculations. The course has 4 units that cover material and energy balance calculations, as well as their applications to chemical and biochemical processes. Unit 1 covers gas laws and composition calculations. Unit 2 applies material balancing to unit operations. Unit 3 covers material balancing of chemical reactions and calculating stoichiometric coefficients. Unit 4 performs energy balancing of reactive and non-reactive processes. The course aims to provide students with skills in various process calculations.

Uploaded by

ARUN K CHOCKALINGAM
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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L T P C

2 1 0 3

Course Code: CHE108


Semester: III

BIOPROCESS CALCULATIONS

Course Objective:
To provide the elements of material balance and energy balance used in chemical and
biochemical industries.

UNIT – I 12 Periods

Basic and derived units; use of mole in calculations; methods of expressing compositions of
mixtures and solutions. Gas systems: ideal and real gas laws; gas constant; calculations of
pressure, volume and temperature, Use of partial pressure & partial volume of a pure
component in gas calculations.

UNIT –II 12 Periods

Application of material balance in unit operations like mixing, filtration, extraction, evaporation,
crystallization and drying. Humidification & dehumidification: calculations of absolute humidity;
molal humidity; saturation humidity; relative humidity, percentage humidity; humid heat; humid
volume and enthalpy. use of humidity in condensation & drying; Use of humidity chart.

UNIT – III 11 Periods

Material balance with chemical reaction; limiting & excess reactants, Stoichiometry of cell
growth & product formation – elemental balances; degrees of reduction of substrate & biomass;
available-electron balances; yield coefficients of biomass & product formation; maintenance
coefficients, problems based on yield coefficients, respiration quotients, reduction ratio.

UNIT – IV 10 Periods

Energy balance - Balance on non-reactive process; effect of pressure and temperature on heat
of reaction. Heat of mixing, heat of solution. Balance on reactive processes; calculations of
heats of reaction; formation and combustion reactions, adiabatic reaction temperature,
Theoretical flame temperature.

TEXTBOOKS

1. Bhatt, B. I. and S. B. Thakore, Stoichiometry, 5/e, Tata McGraw-Hill, New Delhi, 2010.
2. Doran, P.M., Bio process Engineering Principles, 2/e, Academic press, New Delhi, 2013.
(Unit III)
3. Shuler, M., and F. Kargi, Bioprocess Engineering, 2/e, Prentice-Hall, Englewood Cliffs, NJ,
2002. (Units III & IV)
REFERENCES
1. Himmelblau, D.M., Basic Principles and Calculations in Chemical Engineering, 6/e, Prentice-
Hall of India, New Delhi, 1996.
2. Narayanan, K.V., Chemical Engineering Thermodynamics, Prentice-Hall of India, India,
2006. (Unit – I; PVT Relationship)

ONLINE MATERIAL

1. Process design and Economics:


http://nptel.ac.in/syllabus/syllabus.php?subjectId=103103107

UNIT-WISE LEARNING OUTCOMES

Upon completion of each unit, the learner will be able to

Unit - I Perform calculations using P-V-T relationship for ideal and real gases.

Unit - II Perform material balance for various unit operations.

Perform material balance on reactive systems.


Unit - III Calculate the stoichiometric coefficients using elemental and electron
balances.
Carry out energy balance for the various reacting and non-reacting
Unit - IV
systems.

COURSE LEARNING OUTCOMES

Upon completion of this course, the learner will be able to

1. Perform unit conversion calculations between different systems of units


2. Perform calculation using P-V-T relationship for ideal and real gases.
3. Perform overall and component material balance for different unit operations under specified
conditions.
4. Perform overall and component material balance for reactive systems under specified
conditions.
5. Calculate stoichiometric coefficients and yield coefficient for reactions relevance to
bioprocess using material, elemental and electron balances.
6. Perform energy balance for reactive and non-reactive systems under specified conditions.

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