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This document outlines the preparation of a zinc oxide paste. It provides the objective, category, materials, formula, procedure, computations, and questions about the paste. The key ingredients are zinc oxide, starch, and white petrolatum. Zinc oxide (30g) and starch (30g) are triturated in a mortar and pestle and then white petrolatum (60g) is incorporated to make a smooth paste that is placed in an appropriate container.

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Kate Mendoza
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0% found this document useful (0 votes)
257 views4 pages

This Study Resource Was

This document outlines the preparation of a zinc oxide paste. It provides the objective, category, materials, formula, procedure, computations, and questions about the paste. The key ingredients are zinc oxide, starch, and white petrolatum. Zinc oxide (30g) and starch (30g) are triturated in a mortar and pestle and then white petrolatum (60g) is incorporated to make a smooth paste that is placed in an appropriate container.

Uploaded by

Kate Mendoza
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
You are on page 1/ 4

Aiame Marie L.

Taping July 9,
2019

Preparation No.3

I. Objective

To make Zinc Oxide Paste

II. Category

Pharmacological

III. Materials & Ingredients

 Mortar and pestle  Glassine paper


 Spatula  Graduated Cylinder
 Ointment jar (4 pcs. Of  Zinc Oxide
20-30g)  Starch

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 White petrolatum

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IV. Formula

o.
Original Amount Calculated Amount
Zinc Oxide rs e 0.165 g 30 g
ou urc
Starch 82.5 mg 30 g
White petrolatum q.s.ad 1000 g 60 g
To make 120 g
o
aC s
vi y re

V. Procedure

1. Weighed all the ingredients accurately.


2. Triturated Zinc Oxide and starch in a mortar and pestle separately.
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3. Then white petrolatum was incorporated into the mixture to make a


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smooth paste.
4. Placed in an appropriate container then placed a wax paper at the top of
the cap.
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5. Then it was Labeled properly.


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VI. Computation

Zinc Oxide: White Petrolatum:


sh

C.A= 120 g x 250 g 30g+30g=60g


1000 g 120g – 60g= 60g
C.A.= 60g
C.A.= 30 g

Starch:

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C.A= 120 g x 250 g
1000 g

C.A= 30 g

VII. Questions

1. What is the method of administering the paste?


While Ointments is an ointment, is a viscous semisolid preparation
used topically on a variety of body surfaces. These include the skin
an ointment may or may not be medicated.

2. How are paste differ from ointment?


The difference between paste and ointment is that paste is a soft
mixture, in particular: while ointment is (medicine) a viscous
preparation of oils and/or fats, usually containing medication, used
as a treatment or as an emollient.

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3. When do you use paste?

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Paste is used when there is a need for localized treatment of

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dermatological condition where the medication is not targeted for

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systemic delivery.

o.
4. What are the Physical and Chemical properties of the ingredient?
rs e
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Ingredient Quantity Physical Description Uses in the Formula
s
Zinc 30 g  ZnO is a white powder  Zinc oxide is used in a
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Oxide that is insoluble in wide range of cosmetics


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water, and it is widely and personal care


vi y re

used as an additive in products. Zinc oxide is


numerous materials also used by forming a
and products including barrier on the skin to
rubbers, plastics, protect it from
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ceramics, glass, irritants/moisture and


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cement, lubricants, sunscreen products.


paints, ointments,  Zinc oxide is used as a
adhesives, sealants, bulking agent and a
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pigments, foods, colorant. In over-the-


batteries, ferrites, fire counter drug products, it
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retardants, and first- is used as a skin


aid tapes. protectant and a
sunscreen.
sh

Starch 30 g  Pure starch is a white,


tasteless and odorless  Starch is used to make
powder that is foam for packaging. It is
insoluble in cold water used in making sizing for
or alcohol. textiles and papers. The
glucose from starch can
be fermented to biofuel

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ethanol. It is used as filler
in papermaking. It is used
in preparing laundry
starch
 It is also used as a
substitute for talcum
powder and other beauty
and health products. It is
processed to produce
dextrin- a gummy
substance used primarily
in making adhesive.

White 60 g  Petroleum jelly,  This medication is used


Petrolatu petrolatum, white as a moisturizer to treat
m petrolatum, soft or prevent dry, rough,
paraffin, or multi- scaly, itchy skin and

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hydrocarbon, is a minor skin irritations
semi-solid mixture of (e.g., diaper rash, skin

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hydrocarbons (with burns from radiation
carbon numbers therapy).

o.
mainly higher than
rs e 25).
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VIII. Synonyms: “Zinc Paste” is also known as:
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Flowers of zinc Philosopher’s wool Chinese white


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Zinc white Calamine Oxide

IX. Use of the Preparation


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 Zinc paste used as protective coating for mild skin irritations and
abrasions. Can promote the healing of chapped skin and diaper rash.
Works as a mild astringent and has some antiseptic properties
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X. Methods of Preparation
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 Trituration Process-Trituration is the name of several different


methods used to process materials. In one sense, it is a form of
sh

combination (reducing the particle size of a substance). In another


sense, it is the production of a homogeneous material by mixing
component materials thoroughly. Can also refer to the process of
grinding one compound into another to dilute one of the
ingredients, add volume for processing and handling, or to mask
undesirable qualities.

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 Incorporation Process- It is where the components are mixed until a
uniform preparation is attained.

XI. Appropriate Container

Contain in a well-closed container and avoid exposure to temperatures


exceeding 30°C.

XII. Official description of Finished Product

 Zinc Oxide Pate, USP 42

XIII. Recommended Storage Condition

 Storage: Store between 20°C to 25 °C (68°F and 77 °F).

XIV. Label

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Liceo de Cagayan University
College of Pharmacy

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Dr. Aiame L. Taping Prep: 3

Rx

o.
rs e
Zinc Oxide Paste
USP 42
ou urc
FOR EXTERNAL USE ONLY
o
aC s
vi y re
ed d
ar stu
is
Th
sh

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