Cellular Respiration Model SHO
Cellular Respiration Model SHO
A scientific model is a simplified representation of reality that highlights certain key features of a
process like cellular respiration.
2a. Describe in words what these chemical equations tell us about cellular respiration.
2b. Add a reverse arrow to show the hydrolysis of ATP. Why do cells carry out the hydrolysis of ATP?
4. The figure does not show most of the inputs and outputs of cellular respiration. Add the missing
inputs and outputs to the figure. (The electron transport chain needs O2 as an input and produces
H2O. The Krebs cycle produces CO2.)
5. Explain why mitochondria are often called the powerhouse of the cell.
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By Dr. Ingrid Waldron, Dept Biology, Univ Pennsylvania, © 2020. This Student Handout (including a Google Docs version) and Teacher Notes
(with background information and instructional suggestions) are available at https://serendipstudio.org/exchange/bioactivities/modelCR. This
activity is intended to follow "How do organisms use energy?" (https://serendipstudio.org/exchange/bioactivities/energy).
6. List each type of input molecule that is required for cellular respiration. For each type of input
molecule, explain how the body gets this molecule or how this molecule is made inside each cell.
How the Body Gets this Molecule or
Input Molecule
How this Molecule is Made Inside Each Cell
7. Use what you have learned to construct a model of cellular respiration in this drawing of a cell with
a mitochondrion. (In an actual cell there are many mitochondria.)
Write the three stages of cellular respiration in the appropriate blanks.
Label each arrow with an appropriate input or output. (Use the information from question 6
to identify inputs that come from outside vs. inside the cell. For simplicity, this diagram omits
electron transport by NADH, which is discussed on the next page.)
8a. Different types of models have different advantages for understanding cellular respiration.
Complete the table below to describe an advantage of each type of model.
What This Model Contributes to Your Understanding of Cellular Respiration
Chemical equations
(on page 1)
8b. What are some features of cellular respiration that are shown in both types of models?
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Understanding the Structure and Function of Mitochondria
9. Both figures show the Intermembrane space. Explain why this space is called
“Intermembrane”.
10. The paragraph below explains how the electron transport chain (ETC) works with ATP
synthase to make ATP. Use the information in the second figure to fill in each blank with
“intermembrane space” or “matrix”.
The electron transport chain pumps H+ from the matrix to the __________________________ .
Therefore, the concentration of H+ is higher in the intermembrane space and lower in the matrix.
Because of this concentration gradient, H+ tends to diffuse from the _______________________
to the _______________________. The only place that H+ can cross the inner membrane is
through the channels in the ATP synthase molecules. The movement of H+ through ATP synthase
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provides the energy to make ATP. This is similar to how the flow of water through a turbine
provides the energy to generate electricity.
11. Imagine a mitochondrion that has electron transport chain proteins and ATP synthase, but no
inner membrane. Explain why the ATP synthase would not be able to make ATP.
13. Explain how the folded inner membrane of mitochondria contributes to the production of
ATP. (Hint: Use your answers to questions 11 and 12 as the basis for your answer to this
question.)