NCM 107 Hands Out
NCM 107 Hands Out
A. MENSTRUATION
Is the visible manifestation of cyclic physiologic uterine bleeding due to shedding of the
endometrium following invisible interplay of hormones mainly through hypothalamo-pituitary-
ovarian axis.
HYPOTHALAMUS
The release of GnRH (also called luteinizing hormone– releasing hormone, or LHRH) initiates
the menstrual cycle.
With puberty, becomes less sensitive to estrogen feedback; this results in the initiation every
month in females of the hormone GnRH.
GnRH is transmitted to the anterior pituitary gland and signals the gland to begin producing
the gonadotropic hormones FSH and LH.
GnRH is cyclic, menstrual periods also cycle.
Disease that cause deficiency of the releasing factor result in delayed puberty.
Early activation of GnRH lead to abnormally early sexual development or Precocious
Puberty.
PITUITARY GLAND
Under the influence of GnRH, the anterior lobe of the pituitary gland (the adenohypophysis)
produces two hormones that act on the ovaries to further influence the menstrual cycle:
a. FSH - is active early in the cycle and is responsible for maturation of the ovum.
b. LH - becomes most active at the midpoint of the cycle and is responsible for ovulation or
release of the mature egg cell from the ovary and growth of the uterine lining during the
second half of the menstrual cycle.
MITTELSCHMERZ SIGN - acute pain felt on either side of the abdomen during rupture of the
follicle
The ovum is set free from the surface of the ovary, a process termed ovulation. Swept into
the open end of a fallopian tube.
Ovum and the follicular fluid have been discharged from the ovary; the cells of the follicle
remain in the form of a hollow, empty pit.
FSH has done its work at and now decreases in amount
LH, continues to rise in amount and acts on the follicle cells of the ovary
Follicle cells produce lutein, a bright-yellow fluid, the empty follicle, which is then termed a
corpus luteum.
Cervix
During half of the cycle, hormone secretion from the ovary is low, cervical mucus is thick and
scant. Sperm survival is poor.
Estrogen level is high, cervical mucus becomes thin Sperm penetration and survival
are excellent.
Second half of the cycle, cervical mucus again becomes thick Sperm survival is again
poor.
Fern Test - high estrogen surge before ovulation cervical mucus forms fernlike patterns
when placed on a glass slide and allowed to dry. Women who do not ovulate continue
to show the fern pattern throughout the menstrual cycle.
Spinnbarkeit Test - cervical mucus becomes thin and watery and can be stretched into
long strands at the midpoint of
a menstrual cycle
demonstrates high levels of
estrogen are being produced
and ovulation is about to occur.
Physiologic Changes
Ovaries begin to atrophy, reducing estrogen production
Hot flashes
Vaginal dryness
Osteoporosis
Urinary incontinence
SEXUAL HEALTH
B. HUMAN SEXUALITY
DEFINITION OF TERMS
C. SEXUAL DEVELOPMENT
Table 1
Criteria Males Females
Start of growth Around 13 years old After onset of
spurt menses, around
10-12 years old
Growth rate Rapid early growth Sharp decrease
after menses
occur
Growth cessation Early cessation 1-2 years after
onset of menses
Order of sexual 6 months later than females
maturation Completed in 5 years
1. Darkening and thinning
of scrotum and
enlargement of testes
and scrotum – first
visible sign
2. Appearance of body hair
a. Pubic area
b. Axilla
c. Upper lip
d. Face
METHODS OF CONTRACEPTION
1. NATURAL METHOD
Involves no introduction of chemical or foreign material into the body or sustaining from
sexual intercourse during a fertile period
a. Abstinence - refraining from sexual relations
b. Calendar (Rhythm) Method
couple abstains coitus during fertile days
Useful for those experiencing regular menstruation.
Woman observes her menses for 6 straight months and documents the pattern.
To calculate safe days,
the longest cycle is subtracted by 11, this represents last fertile days
The shortest cycle (interval) is subtracted by 18 this result predicts her first fertile
day.
Example:
January – February = 28
February – March = 31
March – April = 26
April – May = 28
May – June = 30
June – July = 27
Longest is 31 (minus 11) = 20
Shortest is 26 (minus 18) = 8
Table 5.1
Factors to Access Menstrual Cycle Phase
Lutheal phase Follicular Phase
Dominant Hormone Progesterone Estrogen
Cervical Mucous
Characteristics Scanty Profuse
– Amount Cloudy, white to yellow Clear
– Color Thick and sticky Thin, watery,
– Consistency slippery, stretchable,
Spinnbarkeit present
at ovulation
2. ARTIFICIAL METHOD
1. Hormonal Contraception
Hormones that cause such fluctuations in a normal menstrual cycle that ovulation does
not occur
a. Oral Contraceptives “The Pill”
2 Types:
Combined Oral Contraceptive (COC)
synthetic estrogen combined
with a small amount of synthetic
progesterone
99.7% effective in preventing
conception when used correctly
not for breastfeeding women
d. Vaginal Insertion
Vaginal ring (NuvaRing) a silicone ring that surrounds
the cervix and continually releases a combination of
estrogen and progesterone.
Inserted vaginally and left in place for 3 weeks, then
removed for 1 week for menstrual flow.
e. Intrauterine Devices
small plastic object that is inserted into the uterus through the vagina
inserted before a woman has had coitus after a menstrual flow
Copper T380 (ParaGard), a T-shaped plastic device wound with copper with 2 nylon
threads at its end. It is effective for 10 years.
Figure 22 (A) Intrauterine device. (B) An IUD in place in the uterus.
Mechanical Barriers
a. Diaphragm a circular rubber disk that is placed over the cervix before intercourse
Should remain in place for at least 6 hours after coitus, it may be left in place for
as long as 24 hours.
Reusable, will last for 2-3 years.
Figure 24. Proper insertion of a
diaphragm. (A) After spermicidal
jelly or cream is applied to the
rim, the diaphragm is pinched
between the fingers and thumb.
(B) The folded diaphragm is then
inserted into the vagina and
pushed backward as far as it will
go. (C) To check for proper
positioning, the woman should
feel the cervix to be certain it is
completely covered by the soft
rubber dome of the diaphragm.
(D) To remove the diaphragm, a
finger is hooked under the
forward rim and the diaphragm is pulled down and out.
Figure 27. A female condom. (A) The REALITY (WP-333) female condom
(B) Insertion technique.
3. Surgical Methods often called sterilization.