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Cetrorelix Drug Study

Cetrotide is a GnRH antagonist used to inhibit premature LH surges in patients undergoing controlled ovarian stimulation. It works by competing with natural GnRH for binding sites on pituitary cells, controlling the release of LH and FSH. Common side effects include stomach pain, bloating, nausea, vomiting, and diarrhea. Nurses monitor for signs of ovarian hyperstimulation syndrome and educate patients on when to contact their physician regarding severe side effects.

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242 views2 pages

Cetrorelix Drug Study

Cetrotide is a GnRH antagonist used to inhibit premature LH surges in patients undergoing controlled ovarian stimulation. It works by competing with natural GnRH for binding sites on pituitary cells, controlling the release of LH and FSH. Common side effects include stomach pain, bloating, nausea, vomiting, and diarrhea. Nurses monitor for signs of ovarian hyperstimulation syndrome and educate patients on when to contact their physician regarding severe side effects.

Uploaded by

happymee927
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Drug Mechanism of Action Indications Side Effects Nursing Responsibility

Generic Name: cetrorelix It competes with natural GnRH for Inhibition of premature LH surges in stomach pain, bloating, nausea, Assessment & Drug Effects
Brand Name: Cetrotide binding to membrane receptors on patients undergoing controlled
pituitary cells and thus controls the ovarian stimulation vomiting, diarrhea, rapid weight Lab test: Monitor routine blood
Classification: GnRH Antagonist release of LH and FSH in a dose- gain, especially in your face and chemistries.
dependent manner. Monitor weight and report
Dosage/Route/Frequency: midsection, little or no urination,
development of edema and/or
3 mg subcutaneously during early pain when you breathe, rapid heart shortness of breath.
follicular pitase or 0.25 mg
rate, feeling short of breath
subcutaneously on day 5 or 6 and
(especially when lying down). Patient & Family Education
then every day until HCG is
administered
Contact physician immediately for
References: any of the following: Abdominal or
https://dailymed.nlm.nih.gov/ stomach pain, persistent or severe
dailymed/fda/fdaDrugXsl.cfm?s Contraindication/s Adverse Reaction/s nausea, vomiting or diarrhea;
etid=aca7768e-28a7-4027-b1d8- Hypersensitivity to cetrorelix Ovarian Hyperstimulation decreased urination; pelvic pain;
e66247665f79&type=display acetate, extrinsic peptide hormones Syndrome , Nausea, Headache moderate to severe bloating, rapid
https://www.everydayhealth.com or mannitol. redness, erythema, bruising, weight gain; shortness of breath;
/drugs/cetrotide Known hypersensitivity to GnRH or itching, swelling, and pruritus swelling of lower legs.
any other GnRH analogs. Understand that hot flashes are a
Known or suspected pregnancy, and common side effect of this drug.
lactation. Do not breast feed while using this
Severe renal impairment drug without consulting physician.

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