Orange Book
Orange Book
Department of Justice
Drug Enforcement Administration
Diversion Control Division
Drug & Chemical Evaluation Section
Lists of:
Scheduling Actions
Controlled Substances
Regulated Chemicals
April 2024
Foreword
The first three sections of this booklet list the names of the substances which are described in the Code of Federal
Regulations (CFR) as well as some of those which generate frequent inquiries. The substances are first arranged
alphabetically, then by Drug Enforcement Administration (DEA) drug code number, and finally by Controlled Substances
Act (21 U.S.C. §801 et seq.) (CSA) schedule.
These lists describe the basic or parent chemical and do not describe the salts, isomers, salts of isomers, esters,
ethers, and derivatives which may be controlled substances. These are not comprehensive lists so please note that a
substance need not be listed as a controlled substance to be treated as a scheduled substance for criminal prosecution.
The “Other Names” column, provides some examples of alternate names for certain compounds, and in some
instances provides examples of “positional isomers”. If outside parties want to ensure that a compound is not
considered a scheduled substance or listed chemical, they should write the DEA, Drug and Chemical Evaluation
Section (DRE), Diversion Control Division, 8701 Morrissette Drive, Springfield, Virginia 22152, for an official
determination.
A substance (not included on these lists) may also be regulated as a controlled substance analogue. A controlled
substance analogue is a substance which is intended for human consumption, is structurally substantially similar to a schedule
I or schedule II substance, is pharmacologically substantially similar to a schedule I or schedule II substance, or is
represented as being similar to a schedule I or schedule II substance and is not an approved medication in the United States.
See 21 U.S.C. § 802(32)(A) for the definition of a controlled substance analogue and 21 U.S.C. § 813 for the schedule.
The next two sections of this booklet list the Federal Register notices through which the DEA has directed substances
to be added, deleted or transferred between schedules of the CSA. The scheduling changes are listed first in alphabetical
order by substance and then in chronological order by effective date. With the exception of anabolic steroids, section 812 of
the CSA lists only those substances which were controlled in 1970 when the law was enacted. Since then, numerous
substances have been added, removed, or transferred from one schedule to another. The current official list of controlled
substances can be found in section 1308 of the most recent issue of Title 21 Code of Federal Regulations Part 1300 to end (21
CFR § 1308) and the final rules which have been published in the Federal Register subsequent to the issuance of the CFR.
The CFR and the Federal Register are available on the U.S. Government Printing Office web site at
https://www.gpo.gov/fdsys/. This information is accessible, also, on the Diversion Control Division’s website at
https://www.deadiversion.usdoj.gov/.
The last section of this booklet identifies the “List I” and “List II” chemicals. Certain commercial transactions
involving these chemicals are regulated by the CSA. See 21 CFR §§ 1309, 1310 and 1313 for details.
These lists are intended as general references and are not comprehensive listings of all controlled substances and
regulated chemicals.
Drug and Chemical Evaluation Section
Diversion Control Division
Drug Enforcement Administration
April 2024
Abbreviations
2C-B = 4-Bromo-2,5-dimethoxyphenethylamine
2C-T-7 = 2,5-Dimethoxy-4(n)-propylthiophenethylamine
BZP = N-Benzylpiperazine
DMT = Dimethyltryptamine
DOM = 4-Methyl-2,5-dimethoxyamphetamine
GBL = Gamma butyrolactone
GHB = Gamma hydroxybutyric acid, gamma hydroxybutyrate,
4-hydroxybutanoic acid, sodium oxybate
LAAM = Levo-alphacetylmethadol
LSD = Lysergic acid diethylamide, lysergide
MDA = 3,4-Methylenedioxyamphetamine
MDE = 3,4-Methylenedioxy-N-ethylamphetamine
MDMA = 3,4-Methylenedioxymethamphetamine
MPPP = 1-Methyl-4-phenyl-4-propionoxypiperidine
P2P = Phenyl-2-propanone, phenylacetone
PCC = 1-Piperidinocyclohexanecarbonitrile
PCE = N-Ethyl-1-phenylcyclohexylamine
PCH = 1-Phenylcyclohexylamine
PCP = 1-(1-Phenylcyclohexyl)piperidine, phencyclidine
PEPAP = 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine
PHP = 1-(1-Phenylcyclohexyl)pyrrolidine
SPA = (-)-1-Dimethylamino-1,2-diphenylethane
TCP = 1-[1-(2-Thienyl)cyclohexyl]piperidine
TCPy = 1-[1-(2-Thienyl)cyclohexyl]pyrrolidine
THC = Tetrahydrocannabinols
THG = Tetrahydrogestrinone
Scheduling Actions
Alphabetical Order
Scheduling Actions
- Alphabetical Order -
*Scheduled under 21 USC 811(h) FINAL ORDER
**Extension of temporary control
NC = Not Controlled PROPOSAL FEDERAL
PUBLICATION PUBLICATION REGISTER EFFECTIVE CSA
SUBSTANCE DATE DATE CITATION DATE SCHEDULE
CSA
SUBSTANCE CSCN SCH NARC OTHER NAMES
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Alphamethadol 9605 I Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Betacetylmethadol 9607 I Y
Betamethadol 9609 I Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Codeine-N-oxide 9053 I Y
Desomorphine 9055 I Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Dimenoxadol 9617 I Y
Dimepheptanol 9618 I Y
Dimethylthiambutene 9619 I Y
Diphenoxylate 9170 II Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Levomoramide 9629 I Y
Levophenacylmorphan 9631 I Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Morpheridine 9632 I Y
Morphine-N-oxide 9307 I Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Norlevorphanol 9634 I Y
Noroxymorphone 9668 II Y
Norpipanone 9636 I Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Phenampromide 9638 I Y
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Piminodine 9730 II Y
Properidine 9644 I Y
Racemoramide 9645 I Y
Serdexmethylphenidate 1729 IV N
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
CSA
SUBSTANCE CSCN SCH NARC OTHER NAMES
Codeine preparations - 200 mg/(100 ml or 100 gm) V Y Cosanyl,Robitussin A-C,Cheracol,Cerose,Pediacof
Difenoxin preparations - 0.5 mg/25 ug AtSO4/du V Y Motofen
Dihydrocodeine preparations 100mg/(100 ml or 100 V Y Cophene-S, various others
gm)
Diphenoxylate preparations 2.5 mg/25 ug AtSO4 V Y Lomotil, Logen
Ethylmorphine preparations 100 mg/(100 ml or 100 gm) V Y
Opium preparations - 100 mg/(100 ml or 100 gm) V Y Parepectolin, Kapectolin PG, Kaolin Pectin P.G.
Amphetamine 1100 II N Dexedrine, Adderall, Obetrol
Methamphetamine 1105 II N Desoxyn, D-desoxyephedrine, ICE, Crank, Speed
Lisdexamfetamine 1205 II N Vyvanse
Amineptine (7-[(10,11-dihydro-5H- 1219 I N
dibenzo[a,d]cyclohepten-5-yl)amino]heptanoic acid)
Mesocarb (N-phenyl-N'-(3-(1-phenylpropan-2-yl)-1,2,3- 1227 I N
oxadiazol-3-ium-5-yl)carbamimidate)
Benzphetamine 1228 III N Didrex, Inapetyl
Cathine 1230 IV N Constituent of "Khat" plant, (+)-norpseudoephedrine
3-Fluoro-N-methylcathinone (3-FMC) 1233 I N 1-(3-fluorophenyl)-2-(methylamino)propan-1-one)
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
CSA
SUBSTANCE CSCN SCH NARC OTHER NAMES
(1-(4-Fluorobenzyl)-1H-indol-3-yl)(2,2,3,3- 7014 I N FUB-144
tetramethylcyclopropyl)methanone
1-(1-Phenylcyclohexyl)pyrrolidine 7458 I N PCPy, PHP, rolicyclidine
1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine 9663 I Y PEPAP, synthetic heroin
1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole- 7083 I N 5F-CUMYL-PINACA; SGT-25
3-carboxamide
1-[1-(2-Thienyl)cyclohexyl]piperidine 7470 I N TCP, tenocyclidine
1-[1-(2-Thienyl)cyclohexyl]pyrrolidine 7473 I N TCPy
1-Methyl-4-phenyl-4-propionoxypiperidine 9661 I Y MPPP, synthetic heroin
2-(2,5-Dimethoxy-4-(n)-propylphenyl) ethanamine (2C- 7524 I N 2C-P
P)
2-(2,5-Dimethoxy-4-ethylphenyl) ethanamine (2C-E) 7509 I N 2C-E
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
Abbreviations: "NARC" = Narcotic, "CSA SCH" = CSA Schedule, "CSCN" = Controlled Substance Code Number
DEA
CHEMICAL
LIST CODE EFFECTIVE
REGULATED CHEMICAL NUMBER NUMBER CITATION DATE
4-PIPERIDONE (piperidin-4-one) including its acetals, its amides, its I 8330 88 FR 21902 5/12/2023
carbamates, its salts, and salts of its acetals, its amides, and its
carbamates, and any combination thereof, whenever the existence of such
is possible
APAA (Alpha-phenylacetoacetamide) and its optical isomers (Effective I 8515 86 FR 24703 6/9/2021
06/09/2021)
APAAN (Alpha-acetoacetonitrile), salts, optical isomers, & salts of optical I 8512 82 FR 32457 8/14/2017
isomer
EPHEDRINE, salts, optical isomers, & salts of optical isomers I 8113 Pub. L. 100-690 3/18/1989
EPHEDRINE - remove exemption for OTC single entity drug product I 8113 Pub. L. 103-200 4/17/1994
EPHEDRINE remove exemption for OTC ephedrine combination products I 8113 Pub. L. 104-237 10/3/1996
and establish a 24 g retail threshold. Threshold remains zero for single
entity products. Mail order report requirements imposed. For more info, see
21 CFR Parts 1309, 1310, 1313.
METHYL ALPHA-PHENYLACETOACETATE (MAPA) and its optical isomers I 8795 86 FR 64362 12/20/2021
N-METHYLEPHEDRINE, salts, optical isomers, & salts of optical isomers I 8115 Pub. L. 101-647 2/27/1991
N-METHYLPSEUDOEPHEDRINE, salts, optical isomers, salts of optical I 8119 Pub. L. 101-647 2/27/1991
isomers
NORPSEUDOEPHEDRINE, salts, optical isomers, & salts of optical isomers I 8317 Pub. L. 100-690 3/18/1989
PHENYLPROPANOLAMINE, salts, optical isomers, & salts of optical I 1225 Pub. L. 100-690 3/18/1989
isomers
PHENYLPROPANOLAMINE -remove exemption for certain OTC I 1225 Pub. L. 104-237 10/3/1997
transactions. Retail threshold of 24 g established for products not distributed
in blister packs. Mail order report requirements imposed. For more info, see
21 CFR Parts 1309, 1310, and 1313.
PMK GLYCIDATE (3,4-MDP-2-P METHYL GLYCIDATE) and its optical and I 8535 86 FR 24703 6/9/2021
geometric isomers (Effective 06/09/2021)
PMK GLYCIDIC ACID (3,4-MDP-2-P METHYL GLYCIDIC ACID) and its I 8525 86 FR 24703 6/9/2021
salts, optical and geometric isomers, and salts of isomers (Effective
06/09/2021)
PSEUDOEPHEDRINE, salts, optical isomers, & salts of optical isomers I 8112 Pub. L. 100-690 3/18/1989
PSEUDOEPHEDRINE -remove exemption for certain OTC transactions. I 8112 Pub. L. 104-237 10/3/1997
Retail threshold of 24 g established for products not distributed in blister
packs. Mail order report requirements imposed. For more info, see 21 CFR
Parts 1309, 1310, and 1313.
N,N-Dimethylamphetamine
Phenyl-2-propanone
Phencyclidine (PCP)
Methamphetamine
Ethylamphetamine
See 21 C.F.R. §§ 1309, 1310, 1313 and 1314
4-Methylaminorex
Methcathinone
Methaqualone
for details
Amphetamine
THRESHOLDS
DEA
Reagent = Chemical
Precursor =
Cocaine
MDMA
Last Update: Apr 15, 2024 Code
Heroin
MDA
MDE
Solvent =
GHB
LSD
Number
1
1. 1-Boc-4-AP 8336 0 0
8
2. 4-Anilinopiperidine 8335 0 0
12
3. 4-Piperidone 8330 0 0
2
4. N-Acetylanthranilic acid 8522 0 0
9
5. Alpha-Phenylacetoacetamide (APAA) 8515 0 0
3
6. Alpha-Phenylacetoacetonitrile (APAAN) 8512 0 0
2
7. Anthranilic acid 8530 30 30
8. Benzaldehyde 8256 4 4
9. Benzyl cyanide 8735 1 1
1
10. Benzylfentanyl 8334 0 0
3&7
11. Ephedrine 8113 0 0
1
12. Ergocristine 8612 0 0
1
13. Ergonovine 8675 0.010 0.010
1
14. Ergotamine 8676 0.020 0.020
1
15. Ethylamine 8678 1 1
16. gamma-Butyrolactone (GBL) 2011 0 0
17. Hydriodic acid 6695 1.7 1.7
1
18. Hypophosphorous acid 6797 0 0
19. Iodine 6699 0 0
LIST I
6545 0 27
45. Methyl ethyl ketone (2-Butanone) 6714 145 1,455
4
46. Methyl isobutyl ketone 6715 N/C 1,523
47. Potassium permanganate 6579 55 500
48. Sodium permanganate 6588 55 500
5&6
49. Sulfuric acid 6552 N/C 347
50. Toluene 6594 159 1,591
1 and its salts
2 and its salts and esters
IMPORTS &
EXPORTS