NERVOUS SYSTEM Concept RNA Notes
NERVOUS SYSTEM Concept RNA Notes
NERVOUS SYSTEM
Nervous System
CNS PNS
SNS PNS
(B)Neuron:-
Each neuron consist of :-
A) Cell body
B) Dendrites
C) One axon.
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NERVOUS SYSTEM
A) Cell body:-
Contain a nucleus surrounded by cytoplasm.
okss neuronal cell body ftuesa free ribosome & prominent cluster of rough endoplasmic recticulam gskrs gS
mUgs Nissl bodies dgrs gSA (Protein synthesis dk dke djrh gSA )
B) Dendrites:- (little tree)
;s neuron dk input or receiving portion gksrk gSA
;s short tapering & highly branch gskrk gsA
C) Axons:- (axis)
;g long thin vkSj cylindrical projection gskrs gS tks cell body ls ,d cone shape elevation ij Join gksrs gs
ftls axon hillock (Small hill) dgrs gsA
Anatomical Classification
1. Multipolar neurons:- Brain & spinal cord esa most neuron blh type ds gksrs gSA
2. Bipolar neurons:- retina of eye, inner ear & olfactory area in the brain eas gskrs gSA
3. Unipolar neurons:- (Pseudounipolar neurons) PNS esa mostly ;gh neuron gksrs gSA bu neuron dh cell body
ganglia esa fLFkr gksrh gSA
Functional classification
1) Sensory or afferent neurons
2) Motor or efferent neurons
3) Interneurons or association neurons
4. NEURO TRANSMITTERS
5. SYNAPSE
Electrical synapse
Chemical synapse
Area where nerve impulse is transmitted from one neuron to other neuron
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NERVOUS SYSTEM
6. Brain
100 bilion neurons & 10 – 15 trillion neuroglia ls brain cuk gskrk gSA
1.3 – 1.4 kg Wt. (1300gm) almost 3lb in adult
Brain ectoderm ls mRiUu gksrk gSA
8. MENINGES:-
Duramater:- Cranial duramater esa nks layer gksrh gSA tcfd spinal duramater esa 1 gh layer gksrh gSA
Arachnoid mater:- Thin, Transperant gksrh gSA
Pia mater
Thin & Vascular gksrh gSA
;g brain stem ds pkjks vksj better difined gksrh gSA
Telachoroidea :- choroid plexus
Note:-
Duramater & SAS ends at the level of lower boarder of S2
Pia mater extend upto tip of coccyx.
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NERVOUS SYSTEM
9. CSF:-
Clear, Transparent, colorless gksrk gSA
Specific gravity:- 1.005.
Modified tissue Fluid gksrk gSA
Brain ds ventricles, Spinal cord & brain ds pkjks vksj fLFkr SAS & center canal of spinal cord esa ik;k tkrk
gSA
CSF replaces lymph in the CNS.
Formation:- Choroid plexuses of lateral ventricles & 3rd & 4th ventricles.
Total quantity = 80 – 150ml (3 – 5 oz)
Rate of Production:- 0.3ml – 0.5 ml/min. (20ml/hour) & 480 – 720 ml/day average (500ml/day)
Normal pressure of CSF:-
Lateral recumbent position :- 10 – 18 cm of H2O (60 – 100 mm of CSF or H2O)
Sitting position:- 30 cm of H2O,
Circulation
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NERVOUS SYSTEM
Absorption in arachnoid villi & granulations and into dural venous sinuses.
Rate of Absorption:- 20ml/hour (480ml/day)
Rate of Absorption & Rate of production same gksrh gSA
Function
Protection
Nutrition
Metabolism
1) Lateral ventricles:-
Rt. & Lt. cerebral hemisphere esa fLFkr gksrs gSA
;s 3rd ventricles ls interventricular foraman ;k foraman of Munro }kjk communicate jgrs gSA
2) Third ventricles:-
;g between two parts of thalamus esa fLFkr gksrk gSA
;s 3rd ventricle 4th ventricles ls cerebral aqueduct }kjk tqMk jgrk gSA
3) Fourth ventricles:-
;g between cerebellum & pons fLFkr gksrk gSA
;g uhps center canal of spinal cord ds lkFk continues gksrk gS o SAS ds lkFk foramina }kjk continues jgrk
gSA
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NERVOUS SYSTEM
11. CEREBRUM
Seat of intelligence
Cerebral cortex:
Folds=gyri or convolutions
Deepest grooves b/w folds: - fissures.
Shallower grooves b/w folds =sulci
nksuks cerebral hemispheres vUnj ls corpus callosum }kjk connected jgrs gS tks fd white mater dk cuk gksrk
gSA
Lobes of cerebram
Frontal lobe
Parietal
Temporal
Occipital
Limbic system dks “emotional brain” Hkh dgrs gSA (Pleasure, pain, affection, fear & anger)
Limbic system olfaction & memory dk dke Hkh djrk gSA
Note:- Aphasia :- Inability use or comprehend words. blesa O;fä words dks vfPN rjg ls use ugh dj ikrk A
12. Thalamus:-
Function:- Relay station
13. Hypothalamus:-
Control of ANS
Production of Hormones
Regulation of emotional & behaviour patterns
Feeding center, satiety center, thirst center & thermoregulating center hypothalamus esa gh fLFkr gskrs gsA
Circadian rhythms & conscious dks cuk;s j[krk gSA
14. Cerebellum
Outer gray matter.
Butter fly shape dk gskrk gSA
Arbor vitae
Function:-
Smooth & coordinates the contractions of skeletal muscles. (Anterior lobe & posterior lobe dk dk;Z gSA)
Posture & balance. (Flocculonodular lobe dk dk;Z gSA)
Ataxia:- disturbances of muscle coordination.
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NERVOUS SYSTEM
Pons:- (Bridge)
Pons esa pneumotaxic & apneustic centers mifLFkr gksrs gSA
Medulla oblongata:-
;g superior part of the spinal cord ds lkFk continues jgrk gSA
Medula oblongata esa Cardiovascular center & vaso motor center & medullary rhythmicity area (control
breathing) mifLFkr gksrs gSA
Medula oblongata esa Vomiting, Swallowing, sneezing, coughing & hiccupping (fgpdh) ds centers (dsUnz)
mifLFkr gksrs gSA
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NERVOUS SYSTEM
Cranial nerve nose, eyes, inner ear, brain stem & spinal cord ls mRiUu (Originate) gksrh gSA
Name:- According to their function & distribution.
Number (roman no. I to XII):- in order of attachment to the brain.
Mnemonic for Cranial Nerves
- Oh Oh Oh To Touch And Feel Very Green Vegetables AH
5. Trigeminal (V) nerve Mixed Conveys impulses for touch, pain & temperature
Ophthalmic (smallest), sensations & proprioception
Maxillary &
mandibular
(Largest)
6. Abducens (VI) nerve Motor Movement of the eyeball (abduction of the eyeball)
7. Facial (VII) nerve Mixed Touch, pain & temp. sensation, proprioception &
test
8. Vestibulocochlear (VIII) nerve Sensory Conveys impulses related to equilibrium
9. Glossopharyngeal (IX) nerve Mixed Taste & somatic sensation (Touch, pain &
Temprature from tongue)
10. Vagus (X) nerve Mixed Taste & somatic sensation (Touch, pain & Temp.
from Epiglotis & pharynx), BP ,
swallowing, coughing, voice production,
GIT & CVS
11. Accessory (XI) nerve Motor Movement of head & pectoral girdle.
Cranial & spinal portion
12. Hypoglossal (XII) nerve Motor Movement of tongue during speech & swallowing
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NERVOUS SYSTEM
17. Brain Waves (EEG)
Mainly neurons of cerebral cortex ds }kjk electrical impulses generate gksrs gS recording these electrical
impulses is electroencephalogram (EEG) dgk tkrk gSA
Father of EEG:- Hans Berger
EEG ls normal function of brain ,oa diseases dks Hkh diagnose fd;k tk ldrk gSA
1) Epilepsy
2) Tumor
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NERVOUS SYSTEM
It is done to assess the level of conscious. It is an important neurological tool. There are 3 parameters.
Motor Response Points:– 6
Obeys a simple response = 6
Localized painful stimuli = 5
Withdrawal to pain = 4
Abnormal flexion (decorticate posturing)=3
Extensor response (decerebrate posturing) = 2
No motor response to pain = 1
Verbal Response Points:– 5
Fully Oriented = 5
Confused conversation = 4
Inappropriate words = 3
Responds with incomprehensible sounds = 2
No verbal response = 1
Eye Opening Points 4
Spontaneous = 4
In response to sounds = 3
In response to pain = 2
No response even to painful stimuli = 1
Interpretation Of Gcs
Below 8 = coma
9 to 12 = moderate injury
13 to 15 = mild injury
Best score =15.
Worst score =3
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DISORDERS OF NERVOUS SYSTEM
Trigeminal Neuralgia
Definition:-
It is also known as tic doulourex. Trigeminal neuralgia is a sensory disorder to the trigeminal
It results in severe recurrent sharp facial pain along the course of trigeminal nerve.
Causes:-
Compression of trigeminal nerve by artery.
Clinical manifestations:-
1. Client has severe pain on the lips, gums or nose or across the checks.
2. Situations that stimulate symptoms include cold washing the face, chewing or food or fluids of
extreme temperatures.
Treatment:-
1. Instruct the client to avoid hot or cold foods and fluids.
2. Provide small feedings of liquid and soft foods.
3. Instruct the client to chew food on the unaffected side.
Definition:-
Normal ICP is 5 to 15 mm Hg. If pressure is increased and causes symptoms then it is known as
increased ICP.
Clinical manifestations:-
1. Altered level of consciousness which is the most sensitive and earliest indication of increasing ICP.
2. Late signs of increased ICP “CUSHING TRIAD”
increased systolic blood pressure,
widened pulse pressure and
slowed heart rate.
Irregular respiration.
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DISORDERS OF NERVOUS SYSTEM
Treatment:-
Assess patency of the airway and keep an airway and emergency equipment at the bedside.
Place the client in a semi fowler’s position.
Change position of the client every 2 hours avoiding injury when turning.
Avoid Trendelenburg’s position
Initiate seizure precautions if necessary.
A hypersomotic agent increases intravascular pressure by drawing fluid from the interstitial spaces and
from the brain cells.
Limit fluid intake to 1200 ml/day
Instruct the client to avoid straining activities, such as coughing and sneezing.
Instruct the client to avoid Valsalva’s maneuvers.
For the client with increased intracranial pressure elevate the head of the bed 30 to 40 degrees, avoid the
Trendelenburg position, and prevent flexion of the neck and hips.
Epidural Hematoma:-
Results from arterial bleeding.
Epidural hematoma forms between the dura and skull from a tear in the meningeal artery.
It is associated with lucid period.
Epidural hematoma is a surgical emergency.
Subdural Hematoma:-
Results from a venous bleed.
Subdural hematoma occurs under the duramater as a result of tears in the veins crossing the subdural
space.
Intracerebral Hemorrhage:-
Intracerebral hemorrhage occurs when a blood vessel within the brain ruptures allowing blood to leak
inside the brain.
Subarachnoid Hemorrhage:-
A subarachnoid hemorrhage is bleeding into the subarachnoid space.
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DISORDERS OF NERVOUS SYSTEM
Tetraphlegia (Quadriplegia):-
Injury occurring between C5 and C8
Paraplegia:-
Injury occurring between T1 - L4 (below C8)
Paralysis involving only the lower extremities
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DISORDERS OF NERVOUS SYSTEM
Types of seizures:-
1. Generalized seizures
2. Partial seizures
Assess behaviour at the onset of the seizure. If the client has experienced an aura, if a change in
facial expression occurred, or if a sound or cry occurred from the client.
If the client is standing or sitting, place the client on the floor and protect the head and body.
Administer oxygen.
Prepare to suction secretions.
Turn the client to the side to allow secretions to drain while maintaining the airway.
Prevent injury during the seizure.
Remain with the client.
Do not restrain the client.
Loosen restrictive do thing.
STATUS EPILEPTICS:- Involves a rapid succession of epileptic spasms without intervals of consciousness
it is a potential complication that can occur with any type of seizure and brain damage may result.
Cerebrovascular accident (CVA) or stroke
Definition:-
It is also known as brain attack. A stroke is a syndrome in which the cerebral circulation is deficiated,
causing neurological deficits.
Causes:-
Thrombosis
Embolism
Hemorrhage from rupture of a cerebral vessel.
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DISORDERS OF NERVOUS SYSTEM
Clinical manifestations:-
BY FAST acronym.
F: facial dropping
A: arm weakness
S: slurring of speech
T: tissue damage
Signs and symptoms of stroke:-
Aphasia: inability to comprehend or use words in right context.
Agnosia the inability to recognize familiar objects or persons.
Apraxia:- Characterized by loss of ability to execute or carry out
skilled movements or gestures,
Hemianopsia;- Blindness in half the visual field
Neglect Syndrome (Unilateral Neglect):- Client Unaware of the existence of his or her paralyzed side.
Treatment of stroke:-
Thrombotic stroke is treated by infusing tissue plasminogen activaters.
Antihypertensive therapy
Antiplatelet therapy
Surgical management is by carotid endarterectomy.
Multiple Sclerosis(MS)
Definition:-
1) Multiple sclerosis is characterized by demyelination of the neurons in CNS.
2) It usually consists of periods of remissions and exacerbations.
Treatment:-
Interferon therapy is used as a treatment modality.
Steroids in high doses are given to reduce nerve edema.
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DISORDERS OF NERVOUS SYSTEM
Causes:-
Lack of dopamine in substantia nigra.
Sign and symptoms:-
Bradykinesia abnormal slowness of movement.
Monotonous speech
Tremors in hands and figures at rest (pill rolling)
Tremors
Rigidity
Blank facial expression masklike faces
Drooling of saliva.
Loss of coordination and balance while walking
Treatment:-
Carbidopa levadopa
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DISORDERS OF NERVOUS SYSTEM
Causes :-
Viral cause : EB virus
Bacterial cause: campylobacter jejuni bacteria.
Postvaccinial causes : after influenza vaccine.
Clinical manifestations:-
Weakness of lower extremities.
Gradual progressive weakness of the upper extremities and facial muscles.
Meningitis
Definition:-
Meningitis is inflammation of the meninges specially arachnoids and pia mater of the brain and spinal cord.
Causes:-
1) Bacteria : E. coli , Hemophilus influenzae.
2) Viral : Mumps Virus, Chicken pox, Herpes, HIV and Coxckie viruses.
3) Protozoal:
4) Fungal :Cryptococcal fungus.
Sign and symptoms:-
Headache, High grade fever
Nuchal rigidity : neck rigidity.
Kerning sign: extension of knee beyond 135 degree causes pain in hamstring.
Brudzinski’s sign: flexion of neck cause flexion knees and hips.
Other signs are:-
Photophobia
Red. Macular rash with meningococcal meningitis.
Diagnosis : BY CSF examination.
Treatments:-
According to causative organism.
Encephalitis
Definition:-
Encephalitis is an inflammation of the brain parenchyma.
Causes:-
Viral encephalitis most common.
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IMPORTANT NOTES
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Nursing Coaching for
AIIMS, DSSB, ESIC, PGIMER, RPSC
RAILWAY, CHO, STAFF NURSE AND NUSRING
TUTOR
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MCQs
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MCQs
1 C 16 B 31 D 46 A 61 B 76 A
2 D 17 B 32 B 47 B 62 B 77 D
3 C 18 A 33 A 48 B 63 B 78 B
4 D 19 D 34 B 49 C 64 B 79 A
5 C 20 A 35 B 50 B 65 C 80 C
6 A 21 B 36 D 51 B 66 C 81 C
7 C 22 B 37 B 52 C 67 A 82 B
8 B 23 B 38 A 53 B 68 C
9 A 24 B 39 B 54 D 69 A
10 C 25 C 40 A 55 B 70 B
11 B 26 A 41 C 56 A 71 B
12 A 27 B 42 C 57 A 72 B
13 B 28 B 43 C 58 D 73 A
14 C 29 C 44 B 59 D 74 D
15 B 30 D 45 C 60 C 75 B
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