Lab Report
Lab Report
K ANV A Name
Age
Mr. PAVAN KUMAR
19 Year(s) Sex Male
DIAGNOSTIC SERVICES PVT. LTD.
Corporate NON CORPORATE
Centre for Hi-tech Diagnostic Services and Multi-Speciality
Polyclinic Integrated with Physiotherapy & Research
Ref. By. C/O ASHIRVAD NH
#2/10, Dr.Rajkumar Rd, 4th N Blk, Rajajinagar, Bangalore - 10
PH: 080 69094001 (30 Lines)
E-Mail : dr.venkatappa@kanvadiagnostic.com MC-2457
WebSite : www.kanvadiagnostic.com
HAEMATOLOGY
Neutrophils 34 % 45 - 75 %
Lymphocytes 57 % 20 - 45 %
Monocytes 9 % 2-9%
Red Blood Corpulses (Dc Detection Method 6.31 millions/cumm 4.5 - 5.9 millions/cumm
by Hydrodynamic Focusing)
Platelet Count (Dc Detection Method by 1.27 Lakhs/cumm 1.5 - 4.5 lakhs/cumm
Hydrodynamic Focusing)
Page 1 of 5
Reg. No. K2982410 Date 21/08/2024 11:07
K ANV A Name
Age
Mr. PAVAN KUMAR
19 Year(s) Sex Male
DIAGNOSTIC SERVICES PVT. LTD.
Corporate NON CORPORATE
Centre for Hi-tech Diagnostic Services and Multi-Speciality
Polyclinic Integrated with Physiotherapy & Research
Ref. By. C/O ASHIRVAD NH
#2/10, Dr.Rajkumar Rd, 4th N Blk, Rajajinagar, Bangalore - 10
PH: 080 69094001 (30 Lines)
E-Mail : dr.venkatappa@kanvadiagnostic.com MC-2457
WebSite : www.kanvadiagnostic.com
HAEMATOLOGY
Page 2 of 5
Reg. No. K2982410 Date 21/08/2024 11:07
K ANV A Name
Age
Mr. PAVAN KUMAR
19 Year(s) Sex Male
DIAGNOSTIC SERVICES PVT. LTD.
Corporate NON CORPORATE
Centre for Hi-tech Diagnostic Services and Multi-Speciality
Polyclinic Integrated with Physiotherapy & Research
Ref. By. C/O ASHIRVAD NH
#2/10, Dr.Rajkumar Rd, 4th N Blk, Rajajinagar, Bangalore - 10
PH: 080 69094001 (30 Lines)
E-Mail : dr.venkatappa@kanvadiagnostic.com
WebSite : www.kanvadiagnostic.com
SEROLOGY
• Dengue fever, a mosquito borne viral infection is caused by distinct, but closely related serotypes of the Dengue virus(Den1,2,3,4 & 5).
• NS1 antigen is a highly conserved ; non structural glycoprotein, produced both in membrane associated and secretory froms, by all serotypes
of Dengue virus.
Note
• Detection of NS1 is dependent on the stage of the disease in which the specimen is collected, hence a negative result does not exclude an
infection.
• Dengue NS1 is detectable in blood from day 1 upto day 9; occasionally upto day 18; post onset of symptoms.
• Recommended to check for Dengue specific antibodies in conjunction with Dengue NS1.
• A definitive clinical interpretation to be made by evaluation of laboratory findings, clinical and exposure history.
•
Significance
• NS1 is an alternative biomarker to both serological and molecular based techniques for diagnosis of acute dengue infection, without the
requirement of paired sera.
• NS1 antigen detection has highest sensitivity in acute phase of the illness.
• High level of antigenemia is a probable indicator of disease severity and correlates with development of Dengue hemorrhagic fever(DHF).
• NS1 Antigen is detectable in both primary and secondary infections. Detection rate is higher in acute primary infection (for up to 9 days; post
onset of symptoms) compared to acute secondary infection(NS1 antigen is detectable for a shorter duration of 1-4 days; post onset of
symptoms.)
Page 3 of 5
Reg. No. K2982410 Date 21/08/2024 11:07
K ANV A Name
Age
Mr. PAVAN KUMAR
19 Year(s) Sex Male
DIAGNOSTIC SERVICES PVT. LTD.
Corporate NON CORPORATE
Centre for Hi-tech Diagnostic Services and Multi-Speciality
Polyclinic Integrated with Physiotherapy & Research
Ref. By. C/O ASHIRVAD NH
#2/10, Dr.Rajkumar Rd, 4th N Blk, Rajajinagar, Bangalore - 10
PH: 080 69094001 (30 Lines)
E-Mail : dr.venkatappa@kanvadiagnostic.com
WebSite : www.kanvadiagnostic.com
SEROLOGY
Result Indications
<0.9 (IgM antibodies not detected) • Absence of infection
• Early acute phase of primary infection
• Secondary infection
• Immunosuppression
0.9 – 1.1 (Equivocal) • Indeterminate (To retest after 2 weeks)
>1.1 (IgM antibodies detected) • Recent,Primary infection
• Secondary infection(low titres)
• Cross reactivity with other Flavi viruses
Dengue IgM is a semi quantitative, invitro assay for detection of human IgM antibodies against Dengue virus.
Note:
• Duration of specimen collection is crucial for presumptive diagnosis and differentiation between primary and secondary Dengue infection.
• IgM antibodies are detectable approximately from day 5 of illness, peaks by two weeks and remains detectable for 2-3 months.
• IgM antibodies are either undetectable or present in low titres in acute phase of secondary infections.
• Testing of convalescent phase serum recommended to check for presence of IgG antibodies to confirm recent infection.
• Negative result does not preclude the possibility of exposure or infection.
• Test result to be interpreted in conjunction with the clinical findings.
Limitations
1. False negativity observed during early acute phase of illness.
2. False positivity seen due to serological cross reactivity with other Flaviviruses and in autoimmune diseases.
Page 4 of 5
Reg. No. K2982410 Date 21/08/2024 11:07
K ANV A Name
Age
Mr. PAVAN KUMAR
19 Year(s) Sex Male
DIAGNOSTIC SERVICES PVT. LTD.
Corporate NON CORPORATE
Centre for Hi-tech Diagnostic Services and Multi-Speciality
Polyclinic Integrated with Physiotherapy & Research
Ref. By. C/O ASHIRVAD NH
#2/10, Dr.Rajkumar Rd, 4th N Blk, Rajajinagar, Bangalore - 10
PH: 080 69094001 (30 Lines)
E-Mail : dr.venkatappa@kanvadiagnostic.com
WebSite : www.kanvadiagnostic.com
SEROLOGY
Limitations :
•
•
False negativity observed during early acute phase of primary infection.
• False positivity observed due to-
1. serological cross reactivity with other Flaviviruses
2. immunisation against yellow fever, Japanese encephalitis and tick borne encephalitis.
Sample Received At
SERUM 21/08/2024 11:13
Verified By : KEYURI
Kruthika Muralidhar
Microbiologist
Page 5 of 5