NBME Laboratory Reference Values
NBME Laboratory Reference Values
SERUM
General Chemistry:
Electrolytes
Sodium (Na+) 136–146 mEq/L 136–146 mmol/L
Potassium (K+) 3.5–5.0 mEq/L 3.5–5.0 mmol/L
Chloride (Cl–) 95–105 mEq/L 95–105 mmol/L
Bicarbonate (HCO3–) 22–28 mEq/L 22–28 mmol/L
Urea nitrogen 7–18 mg/dL 2.5–6.4 mmol/L
Creatinine 0.6–1.2 mg/dL 53–106 μmol/L
Fasting: 70–100 mg/dL 3.8–5.6 mmol/L
Glucose
Random, non-fasting: <140 mg/dL <7.77 mmol/L
Calcium 8.4–10.2 mg/dL 2.1–2.6 mmol/L
Magnesium (Mg2+) 1.5–2.0 mg/dL 0.75–1.0 mmol/L
Phosphorus (inorganic) 3.0–4.5 mg/dL 1.0–1.5 mmol/L
Hepatic:
Alanine aminotransferase (ALT) 10–40 U/L 10–40 U/L
Aspartate aminotransferase (AST) 12–38 U/L 12–38 U/L
Alkaline phosphatase 25–100 U/L 25–100 U/L
Bilirubin, total // direct 0.1–1.0 mg/dL // 0.0–0.3 mg/dL 2–17 μmol/L // 0–5 μmol/L
Proteins, total 6.0–7.8 g/dL 60–78 g/L
Albumin 3.5–5.5 g/dL 35–55 g/L
Globulin 2.3–3.5 g/dL 23–35 g/L
Other, serum:
Amylase 25–125 U/L 25–125 U/L
Lipase 13–60 U/L 13–60 U/L
Male: 97–137 mL/min 97–137 mL/min
Creatinine clearance
Female: 88–128 mL/min 88–128 mL/min
Male: 25–90 U/L 25–90 U/L
Creatine kinase
Female: 10–70 U/L 10–70 U/L
Lactate dehydrogenase 45–200 U/L 45–200 U/L
Osmolality 275–295 mOsmol/kg H2O 275–295 mOsmol/kg H2O
Troponin I ≤0.04 ng/mL ≤0.04 µg/L
Uric acid 3.0–8.2 mg/dL 0.18–0.48 mmol/L
1 | Laboratory Values
Laboratory Values (continued)
Reference Range SI Reference Intervals
Lipids:
Cholesterol
Total Normal: <200 mg/dL <5.2 mmol/L
High: >240 mg/dL >6.2 mmol/L
HDL 40–60 mg/dL 1.0–1.6 mmol/L
LDL <160 mg/dL <4.2 mmol/L
Normal: <150 mg/dL <1.70 mmol/L
Triglycerides
Borderline: 151–199 mg/dL 1.71–2.25 mmol/L
Iron Studies:
Male: 20–250 ng/mL 20–250 μg/L
Ferritin
Female: 10–120 ng/mL 10–120 μg/L
Male: 65–175 µg/dL 11.6–31.3 μmol/L
Iron
Female: 50–170 μg/dL 9.0–30.4 μmol/L
Total iron-binding capacity 250–400 µg/dL 44.8–71.6 μmol/L
Transferrin 200–360 mg/dL 2.0–3.6 g/L
Endocrine:
Male: 4–25 mIU/mL 4–25 IU/L
Female: premenopause 4–30 mIU/mL 4–30 IU/L
Follicle-stimulating hormone
midcycle peak 10–90 mIU/mL 10–90 IU/L
postmenopause 40–250 mIU/mL 40–250 IU/L
Male: 6–23 mIU/mL 6–23 IU/L
Female: follicular phase 5–30 mIU/mL 5–30 IU/L
Luteinizing hormone
midcycle 75–150 mIU/mL 75–150 IU/L
postmenopause 30–200 mIU/mL 30–200 IU/L
Fasting: <5 ng/mL <5 μg/L
Growth hormone - arginine stimulation
Provocative stimuli: >7 ng/mL >7 μg/L
Male: <17 ng/mL <17 μg/L
Prolactin (hPRL)
Female: <25 ng/mL <25 μg/L
0800 h: 5–23 μg/dL 138–635 nmol/L
Cortisol 1600 h: 3–15 μg/dL 82–413 nmol/L
2000 h: <50% of 0800 h Fraction of 0800 h: <0.50
TSH 0.4–4.0 μU/mL 0.4–4.0 mIU/L
Triiodothyronine (T3) (RIA) 100–200 ng/dL 1.5–3.1 nmol/L
Triiodothyronine (T3) resin uptake 25%–35% 0.25–0.35
Thyroxine (T4) 5–12 μg/dL 64–155 nmol/L
Free T4 0.9–1.7 ng/dL 12.0–21.9 pmol/L
Thyroidal iodine (123I) uptake 8%–30% of administered dose/24 h 0.08–0.30/24 h
Intact PTH 10–60 pg/mL 10–60 ng/L
Male: 3.0–10.0 mg/24 h 8.2–27.6 μmol/24 h
17-Hydroxycorticosteroids
Female: 2.0–8.0 mg/24 h 5.5–22.0 μmol/24 h
Male: 8–20 mg/24 h 28–70 μmol/24 h
17-Ketosteroids, total
Female: 6–15 mg/24 h 21–52 μmol/24 h
2 | Laboratory Values
Laboratory Values (continued)
Immunoglobulins:
IgA 76–390 mg/dL 0.76–3.90 g/L
IgE 0–380 IU/mL 0–380 kIU/L
IgG 650–1500 mg/dL 6.5–15.0 g/L
IgM 50–300 mg/dL 0.5–3.0 g/L
CEREBROSPINAL FLUID
Cell count 0–5/mm3 0–5 × 106/L
Chloride 118–132 mEq/L 118–132 mmol/L
Gamma globulin 3%–12% total proteins 0.03–0.12
Glucose 40–70 mg/dL 2.2–3.9 mmol/L
Pressure 70–180 mm H2O 70–180 mm H2O
Proteins, total <40 mg/dL <0.40 g/L
HEMATOLOGIC
Complete Blood Count:
Male: 41%–53% 0.41–0.53
Hematocrit
Female: 36%–46% 0.36–0.46
Male: 13.5–17.5 g/dL 135–175 g/L
Hemoglobin, blood
Female: 12.0–16.0 g/dL 120–160 g/L
Mean corpuscular hemoglobin (MCH) 25–35 pg/cell 0.39–0.54 fmol/cell
Mean corpuscular hemoglobin conc.
31%–36% Hb/cell 4.8–5.6 mmol Hb/L
(MCHC)
Mean corpuscular volume (MCV) 80–100 μm3 80–100 fL
Volume
Male: 25–43 mL/kg 0.025–0.043 L/kg
Plasma
Female: 28–45 mL/kg 0.028–0.045 L/kg
Male: 20–36 mL/kg 0.020–0.036 L/kg
Red cell
Female: 19–31 mL/kg 0.019–0.031 L/kg
Leukocyte count (WBC) 4500–11,000/mm3 4.5–11.0 × 109/L
Neutrophils, segmented 54%–62% 0.54–0.62
Neutrophils, bands 3%–5% 0.03–0.05
Lymphocytes 25%–33% 0.25–0.33
Monocytes 3%–7% 0.03–0.07
Eosinophils 1%–3% 0.01–0.03
Basophils 0%–0.75% 0.00–0.0075
Platelet count 150,000–400,000/mm3 150–400 × 109/L
3 | Laboratory Values
Laboratory Values (continued)
Reference Range SI Reference Intervals
Coagulation:
Partial thromboplastin time (PTT/aPTT)
25–40 seconds 25–40 seconds
(activated)
Prothrombin time (PT) 11–15 seconds 11–15 seconds
D-dimer ≤250 ng/mL ≤1.4 nmol/L
Other, Hematologic:
Reticulocyte count 0.5%–1.5% 0.005–0.015
Male: 4.3–5.9 million/mm3 4.3–5.9 × 1012/L
Erythrocyte count (RBC)
Female: 3.5–5.5 million/mm3 3.5–5.5 × 1012/L
Erythrocyte sedimentation rate Male: 0–15 mm/h 0–15 mm/h
(Westergren) Female: 0–20 mm/h 0–20 mm/h
CD4+ T-lymphocyte count ≥500/mm3 ≥0.5 × 109/L
Endocrine:
Hemoglobin A1c ≤6% ≤42 mmol/mol
URINE
Calcium 100–300 mg/24 h 2.5–7.5 mmol/24 h
Osmolality 50–1200 mOsmol/kg H2O 50–1200 mOsmol/kg H2O
Oxalate 8–40 μg/mL 90–445 μmol/L
Proteins, total <150 mg/24 h <0.15 g/24 h
4 | Laboratory Values