1. Stabilize airway by intubating and start oxygen to address hypoxemia
2. Rapidly correct shock with fluid bolus and pressors to maintain adequate MAP
3. Control seizures by loading anti-seizure medications
4. Reduce ICP through sedation, head elevation, hyperosmotic therapy, and avoiding lumbar puncture given the low GCS
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Raised ICP Nurses
1. Stabilize airway by intubating and start oxygen to address hypoxemia
2. Rapidly correct shock with fluid bolus and pressors to maintain adequate MAP
3. Control seizures by loading anti-seizure medications
4. Reduce ICP through sedation, head elevation, hyperosmotic therapy, and avoiding lumbar puncture given the low GCS
Changes in pupil size Papilloedema Management of raised ICP Complications Tier one : Stabilization
Airway : even if adequately breathing, early
intubation, ventilation and deep sedation are indicated Indications for intubation – 1. GCS < 8, or fall in GCS by 2 points 2. Evidence of herniation 3. airway compromise / irregular breathing 4. Hypoxemia / hypercarbia Breathing: Circulation: Rapid correction of shock with NS & inotropes to maintain MAP > 50 th centile for age CPP targeted therapy
CPP = MAP – ICP
Maintain CPP > 60 mm Hg in adolescents, > 50 mm Hg in 1 yr – 12 yrs > 40 mm Hg in Infants Calculate MAP target for the three age groups
(Clue: Raised ICP > 20 mm Hg)
CPP targeted therapy
CPP = MAP – ICP
Maintain CPP > 60 mm Hg in adolescents, > 50 mm Hg in 1 yr – 12 yrs > 40 mm Hg in Infants Calculate MAP target for the three age groups CPP = MAP + ICP Infants MAP target = CPP + ICP = 40 + 20 = 60 Children MAP target = CPP + ICP = 50 + 20 = 70 Adolescents MAP target = CPP + ICP = 60 + 20 = 80 Management of raised ICP Nursing pearls…CLUSTER NURSING Hyperosmotic agents Mannitol, 3% saline CSF drainage with EVD Anti seizure medications LP IS CONTRAINDICATED IN CHILD WITH LOW GCS Thiopentone coma Therapeutic hypothermia Conclusion
Patients presenting with altered mental status is
a medical emergency Systematic approach to stabilization and diagnosis will be rewarding in majority Family needs to be counselled with honesty and sensitivity Survival and long term prognosis difficult to predict at the initial stages of illness CASE SCENARIO
10 year old child with h/o fever x 1 day
Seizures x 1 day, multiple episodes Altered sensorium x 8 hours On examination, GCS E3V1M4, PEARL, Noisy breathing with gurgling sounds. BP 70 / 40 mm Hg. SPO2 84% What are the management priorities? Maintain airway, start oxygen Fluid bolus -> Noradrenaline Intubate and sedate Load with phenytoin 20 mg/kg Maintain euthermia, paracetamol Q6H Maintain euglycemia Head in midline, cluster nursing, 3% Saline Antibiotics, withold LP Sedation before suctioning, oral care Prevent bedsores, early enteral feeds