lopinavir (Q422585)

0 references

1 reference

Lopinavir (English)

imported from Wikimedia project

17 November 2015

Lopinavir.svg
1,800 × 1,900; 27 KB

1 reference

German Wikipedia

mass

628.362 dalton

1 reference

Lopinavir (English)

19 October 2016

(2R) epimer-lopinavir

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(4R) epimer-lopinavir

2 references

D-valine diastereomer-lopinavir

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(2R,4R) diastereomer-lopinavir

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chemical formula

C₃₇H₄₈N₄O₅

1 reference

Lopinavir (English)

19 November 2016

CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O

1 reference

Lopinavir (English)

19 November 2016

CC1=C(C(=CC=C1)C)OCC(=O)N[C@@H](CC2=CC=CC=C2)[C@H](C[C@H](CC3=CC=CC=C3)NC(=O)[C@H](C(C)C)N4CCCNC4=O)O

1 reference

Plasmodium falciparum hexose transporter

Lopinavir (English)

19 November 2016

1 reference

The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir.

medical condition treated

1 reference

human immunodeficiency virus infectious disease

13 December 2016

1 reference

Lopinavir-ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

13 December 2016

1 reference

significant drug interaction

bosentan

1 reference

High-priority drug–drug interactions for use in electronic health records

carbamazepin

1 reference

High-priority drug–drug interactions for use in electronic health records

rifabutin

1 reference

High-priority drug–drug interactions for use in electronic health records

rifampicin

1 reference

High-priority drug–drug interactions for use in electronic health records

rifapentine

1 reference

High-priority drug–drug interactions for use in electronic health records

erythromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-methadone

withdrawal symptom

1 reference

probably

A reference set of clinically relevant adverse drug-drug interactions

buprenorphine

central respiratory depression

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

posaconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

rosuvastatin

rhabdomyolysis

1 reference

A reference set of clinically relevant adverse drug-drug interactions

rosuvastatin

muscular disease

1 reference

A reference set of clinically relevant adverse drug-drug interactions

atorvastatin

rhabdomyolysis

1 reference

A reference set of clinically relevant adverse drug-drug interactions

atorvastatin

muscular disease

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Ketoconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

US pregnancy category C

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category D

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Lopinavir

last update

1 September 2017

subject has role

xenobiotic-transporting ATPase inhibitor

1 reference

5 March 2018

HIV protease inhibitors

2 references

5 March 2018

Medical Subject Headings

MeSH descriptor ID

D061466

cytochrome P-450 CYP3A inhibitors

15 March 2018

1 reference

CAS COVID-19 Anti-Viral Candidate Compounds

Medical Subject Headings

15 March 2018

0 references

1 reference

1 reference

Lopinavir

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catalog

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Identifiers

InChI

InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1

1 reference

Lopinavir (English)

19 November 2016

2 references

Lopinavir (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

192725-17-0

2 references

lopinavir (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=192725-17-0

9 April 2021

1 reference

Lopinavir (English)

19 November 2016

2 references

Lopinavir (English)

19 November 2016

Reaxys registry number

9309881

1 reference

lopinavir (English)

19 October 2016

mapping relation type

2 references

LOPINAVIR (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1

1 reference

LOPINAVIR (English)

19 November 2016

2 references

MSBNK-Athens_Univ-AU228801

1 reference

MassBank accession ID

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MSBNK-Athens_Univ-AU228802

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MSBNK-Athens_Univ-AU228803

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MSBNK-Athens_Univ-AU228804

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MSBNK-Athens_Univ-AU228805

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MSBNK-Athens_Univ-AU228806

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SPLASH

splash10-0532-1900601000-f85a252f1640f27563a8

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HSDB ID

8138

1 reference

Hazardous Substances Data Bank

28 October 2019

Lopinavir (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

DTXCID6026456

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LiverTox ID

Lopinavir

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ECHA Substance Infocard ID

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Lopinavir

0 references

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0 references

1 reference

lopinavir (English)

19 November 2016

1 reference

Human Metabolome Database ID

HMDB0015539

2 references

2 references

lopinavir (English)

19 November 2016

NDF-RT ID

N0000148672

1 reference

lopinavir (English)

19 November 2016

0 references

1 reference

1 reference

lopinavir (English)

19 October 2016

1 reference

Immune Epitope Database and Analysis Resource

lopinavir (English)

19 October 2016

1 reference

1 March 2022

0 references

0 references

1 reference

28 October 2013

1 reference

9 July 2020

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

1MUI (English)

19 October 2016

1 reference

2RKG (English)

19 October 2016

1 reference

2RKF (English)

19 October 2016

1 reference

1RV7 (English)

19 October 2016

1 reference

2Q5K (English)

19 October 2016

1 reference

2O4S (English)

19 October 2016

1 reference

3OGQ (English)

19 October 2016

1 reference

2QHC (English)

19 October 2016

1 reference

4L1A (English)

19 October 2016

1 reference

2Z54 (English)

19 October 2016

1 reference

lopinavir (English)