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马安那莫单抗

维基百科,自由的百科全书
马安那莫单抗
单克隆抗体
种类Fab片段英语Fab fragment
目標TAG-72
臨床資料
ATC碼
  • 未分配
识别信息
CAS号1370261-50-9  checkY
ChemSpider
  • none
UNII

马安那莫单抗INN:anatumomab mafenatox;开发代号:ABR-214936)是一种小鼠单克隆抗体,研究用于治疗非小细胞肺癌英语Non-small cell lung cancer[1]它充当肿瘤靶向的超抗原[2]

它是一种人类肿瘤相关5T4抗原单克隆IgG1 Fab片段英语Fragment antigen-binding金黄色葡萄球菌肠毒素(即mafenatox)的融合蛋白[3]

马安那莫单抗的研发于2005年中止。[4]

参考资料

[编辑]
  1. ^ Active Biotech. activebiotech.com. [25 May 2016]. (原始内容存档于2016-08-16). 
  2. ^ Hedlund G, Forsberg G, Nederman T, Sundstedt A, Dahlberg L, Tiensuu M, Nilsson M. Tumor-Targeted Superantigens. Fusion Protein Technologies for Biopharmaceuticals. 2013: 365–381. ISBN 9781118354599. doi:10.1002/9781118354599.ch24. 
  3. ^ Drug info (PDF). World Health Organization. [25 May 2016]. (原始内容存档 (PDF)于2012-02-19). 
  4. ^ Anatumomab mafenatox. AdisInsight. Springer Nature Switzerland AG. [2024-04-26]. (原始内容存档于2024-04-26). 
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