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补体受体

维基百科,自由的百科全书
补体受体
鑑定
標誌Complement receptor
膜蛋白數據庫英语Membranome116

补体受体(英語:complement receptor)是补体系统中的受体,是先天免疫系統的一部分。当有病原体入侵时,可通过抗体或其他途径激活补体蛋白切割为活性形式,再与细胞表面的补体受体结合,激活下一步反应[1]

列表

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CR 名称 配体[1] CD
CR1 C3b, C4b, iC3b CD35
CR2 C3d, iC3b, C3dg, EB病毒 CD21
CR3 , 巨噬细胞-1抗原整合素αMβ2 iC3b CD11b+CD18
CR4 ,整合素αXβ2或 "p150,95" iC3b CD11c+CD18
C3a受体 C3a -
C5a受体 C5a CD88

参考文献

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  1. ^ 1.0 1.1 Janeway, CA Jr; Travers P; Walport M; et al. The complement system and innate immunity. Immunobiology: The Immune System in Health and Disease. New York: Garland Science. 2001 [29 December 2017]. (原始内容存档于2020-01-09). 

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