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Course Title: Bioprocess Engineering: L T S SW/ FW P Total Credit Units

This course covers the fundamentals of bioprocess engineering including cell growth kinetics, mass transfer operations, reaction kinetics, downstream processing techniques, and applications. Students will learn about topics like oxygen transfer, stoichiometric analysis, membrane separation, and bioreactor design. Assessment includes continuous assessments, internal assessments, homework assignments, quizzes, and an end term examination.

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Drishti Malhotra
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63 views3 pages

Course Title: Bioprocess Engineering: L T S SW/ FW P Total Credit Units

This course covers the fundamentals of bioprocess engineering including cell growth kinetics, mass transfer operations, reaction kinetics, downstream processing techniques, and applications. Students will learn about topics like oxygen transfer, stoichiometric analysis, membrane separation, and bioreactor design. Assessment includes continuous assessments, internal assessments, homework assignments, quizzes, and an end term examination.

Uploaded by

Drishti Malhotra
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Course Title: Bioprocess Engineering

L T S SW/ P TOTAL
FW CREDIT
Course Code: FOOD414 Credit Units: UNITS
2 - - - - 2

Course Objectives: This course explains the fundamentals of cell growth and product production and techniques involved in mass transfer operations

Pre-requisites: Basics of Mass Transfer and Unit operations

Course Contents/Syllabus:

Weightage (%)

Module I : Basic of Mass Transfer 15


Mass Transfer in bioprocessing Operation; Theories of Diffusional mass transfer; Mass transfer by convection; Oxygen transfer
Methodology and importance; Factor affecting oxygen transfer rate
Module II : Stoichiometric Analysis 25
Stoichiometry of microbial growth and product formation; Elemental balances; degree of reduction of substrate and biomass, Yield
coefficients of biomass and product formation, maintenance coefficients, Energetic analysis of microbial growth and product formation;
thermodynamic efficiency of growth. Prediction of Yield coefficient
Module III : Reaction Kinetics 20
Reaction kinetics for biological systems- Michaelis Menten kinetics, enzyme deactivation kinetics; heterogenous reactions in
bioprocessing- concentration gradients and reaction rates in solid catalysts.
Module IV : Downstream Processing 30
Recovery and purification of products; Strategies to recover and purify products; filtration; Sedimentation; Centrifugation; Cell
Disruption; Extraction; Membrane Separation; Chromatography; Crystaliztion; Drying
Module V : Applications 10
Examples of Aerobic and Anaerobic Bioprocesses

Student Learning Outcomes:


On completion of the course, the student should be familiarized with the following:
Cell growth kinetics,
Mass transfer involve in bioreactor,
Downstream product recovery

Pedagogy for Course Delivery:


(a) Lecture Plan/Session Plan : The course pedagogy will include lectures, discussion on applications of the topics covered.

(b) Lab/ Practicals:

List of Experiments

Assessment/ Examination Scheme:

Theory L/T (%) Lab/Practical/Studio


(%)
100% 0%

Theory Assessment (L&T):

Continuous Assessment/Internal Assessment End Term Examination

Components (Drop down) CT S/V/Q HA A EE

Weightage (%) 10 08 07 05 70
Lab/ Practical/ Studio Assessment: NA

Continuous Assessment/Internal Assessment End Term Examination

Components (Drop down

Weightage (%)

Text & References:

 McCabe L. Warren, Smith C. Julian and Peter Harriott, “Unit Operations of Chemical Engineering”, 6th ed., McGraw Hill International Edition, New
York, 2001.
 Michael L. Shuler, Fikret Kargi, “Bioprocess Engineering” 2nd Edn., Prentice Hall of India, New Delhi, 2003.
 Bailey, J.E. and Ollis, D.F., “Biochemical Engineering Fundamentals”, 2nd ed., McGraw Hill Book company, 1986.

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