Physiology MCQs
Physiology MCQs
org
MCQs of physiology
the primary forces moving water molecules from the interstitial fluid to plasma include
active trasport
interstitial colloid osmotic pressure
plasma colloid osmotic pressure
interstitiqal hydrostatic pressure
plasma hydrostatic pressure
in a normal 30 years old man the volume of disteribution of Deterim oxide,inulin and
Evan’s blue dye were found to be 42,14 and 4 liters repectively.this means:
body weigt is about 60 Kg
intracellular fluid volume is about 28 liters
total body water can not be calculated from this data
interstitial fluid volume is about 12 liters
plasma volume is about 4 liters
the intracellular fluid volume differs from the intracellular fluid in the following except:
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higer protein concentration
lower chloride concentration
lower osmolarity
lower pH
lower calcium concentration
1-During inspiration;
a. alveolar pressure decreases before pleural pressure
b. pressure in trachea decreases before alveolar pressure decreases
c. pressure in trachea decreases more than alveolar pressure
d. pleural pressure decreases more than alveolar pressure
e. transpulmonary pressure decreases
2-Diffusing capacity of O2 in the lung:
a. dose not change during exercise
b. is equal to diffusing capacity of CO2
c. is directly related to alveolar capillary surface area
d. is the same is in sea level residents and residents at 3000 m altitude
e. is usually measured using carbon dioxide
3-Reduced affinity of hemoglobin to O2
a. is known as the haldan’s seffect
b. favors uptake of O2 at the lung
c. can be caused by increased plasma (H+)
d. is signified by reduced P50
e. is signified by s left shift of the hemoglobin- O2 dissociation curve
4-The following information were obtained from a subject; tidal volume of 500 ml,
dead space volume of 100 ml, respiratory rate of 15 breath/minute and cardiac
output 6 liters/minute. All the following are correct except:
a. his alveolar ventilation 6 liters/minute
b. V/Q is 1
c. His pulmonary ventilation is 7.5 liters/minute
d. His vital capacity can be calculated from the data provided
e. His dead space ventilation is 1.5 liters/minute
5-Regarding the functional residual capacity (FRC), all statements below are
correct expect:
a. FRC increases when lung elasticity increases
b. FRC is higher in elderly than young adults
c. FRC reflects the balance between lung and chest wall elasticity
d. FRC can not be measured with simple spirometry
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e. FRC increases with emphysema
6-Bronchodilatation is likely to produced by:
a. cholinergic muscarinic agonists
b. ß2 adrenergic antagonists
c. ß2 adrenergic agonists
d. leukatriens
7-The peripheral chemoreceptors:
a. are activated only by hypoxia
b. quickly adapt to hypoxia
c. are the major site through which CO2 stimulate ventilation
d. are stimulated both by hypoxic and atagnant hypoxias
e. do not play a role in the hyperpnea high altitude
8-An increase in 2.3 diphosphoglycerate:
a. shift the hemoglobin – O2 dissociation curve to the same side as does metabolic
acidosis
b. shifts hemoglobin – O2 dissociation curve the same side as hypothermia
c. affects hemoglobin F more than hemoglobin A
d. reduces the P20 of hemoglobin
e. is expected to occur in metabolic acidosis
9-Surfactant:
a. is produced by type 1 alveolar epithelial cells
b. production is slow
c. increases lung compliance
d. is a glycoprotein
e. production starts only after deliver of term babies
10-In quite breathing expiration is:
a. passive and due to elastic lung tissue alone
b. passive and both to surface tension and elastic tissue
c. active due intercostals muscles
d. accompanied by an increase in the recoil force of the lung
e. accompanied by an increase in the transpulmonary pressure
11-Blood taken from the pulmonary artery is likely to have:
a. higher hematocrit than arterial blood
b. O2 percent saturation of 50%
c. Higher pH than arterial blood
d. PCO2 of about 40 mm Hg
e. None of the above
12-The V/Q of three alveoli were found to be as follows; alveolus A is 1 alveolus B is
0.5 alveolus C is 2. All the following are correct except:
a. blood leaving alveolus B will have PO2 higher than normal
b. blood leaving alveolus C will have PO2 lower than normal
c. blood leaving alveolus A will have PO2 of about 100 mm Hg
d. alveolus B represents wasted ventilation
e. alveolus A represents wasted ventilation
13-Cyanosis:
a. is caused by low hemoglobin concentration
b. is caused by high concentration of carboxyhemoglobin
c. may be caused by hypoxic or stagnant hypoxia
d. its occurrence is related to the proportion and not the absolute concentration of
reduced hemoglobin
14-The rhythemicity center:
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a. is located in the pons
b. is spontaneously active
c. activity causes expiration
d. activity is increased by pneumotaxic center
e. activity is increased by a rise in blood pressure
15-All the following afferent are in the vagus nerve except those enervating:
a. the carotid body
b. lung stretch receptors
c. aortic chemoreceptors
d. j receptors
16-Hypoventiation may lead to:
a. low plasma HCO3
b. low PCO2 in venous blood
c. high PCO2 in arterial blood
d. low ionized serum calcium
e. shift of the hemoglobin oxygen dissociation to the left
17-The vital capacity:
a. is higher in the elderly than young adults
b. increases following destruction of lung elastic fibers
c. more than 80% of it expired in the first second of forced expiration
d. is twice as much in females than in males
e. is increased by surfactant deficiency
18-Spontaneous respiration stops after:
a. transaction of the brain stem above the pons
b. transaction of the brain stem at the caudal end of the medulla
c. bilateral vagotomy combined with transaction of the brain stem above the pons
d. transaction of the spinal cord between the 6th and 7th cervical segments
e. cutting both the right and left phrenic nerves
19- Pulmonary fibrosis would be expected to produce:
a. hidtotoxic hypoxia
b. stagnant hypoxia
c. decreased vital capacity
d. emphysema
e. increased compliance
20-Which of the following has the greatest affect on the capacity of blood to
transport O2:
a. solubility of oxygen in blood
b. hemoglobin concentration
c. pH of plasma
d. PCO2 of blood
e. Temperature of the blood
21-In the body the metabolism of 10 grams of protein would produce
approximately:
a. 10 kcal
b. 53 kcal
c. 41 kcal
d. 90 kcal
e. 20 cal
22-For measurement of the basal metabolic rate all the following conditions are
required except:
a. mental rest
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b. physic rest
c. normal body temperature
d. 12 hours fasting prior to measurement
e. comfortable room temperature
39-The following is not true about the endplate potential of skeletal muscle cell:
a. its magnitude is proportional to the amount of acetylcholine released by the
motor neurone
b. its magnitude is proportional to the number of acetylocoline receptors in the
endplate
c. is an action potential
d. it can be abolished by curare
e. is low in myasthenia gravis
40-The excitability of neurons is increased by:
a. hypocalcaemia
b. hyponatraemia
c. hypokalaemia
d. hypermagnesaemia
e. hypercalcaemia
41-Myelin:
a. is important in the peripheral nerves but not the central nervous system
b. is formed by the microglial cells
c. is an insulator
d. decreased the speed of transmission of action potentials
e. is carbohydrate in nature
42-The following is not a future of chemical synapses:
a. convergence
b. divergence
c. synaptic
d. transmission of impulse in both directions
e. postsynaptic inhibitory potential
43-The globin part of haemoglobin F consists of:
a. 2 and 2 chains
b. 2 and 2 chains
c. 2 and 2 chains
d. 2 and 2 chains
e. 2 and 2 chains
44-The following are natural anticoaguans except:
a. thromboxane A2
b. prostacycline
c. protein C
d. antithrombin III
e. plasminogen
45- Concearning vitamin B12:
a. is a fat soluble vitamin
b. is found in green vegetable
c. is absorbed in theduodenum
d. antagonized folic acid
e. is required for myelin formation
46-Physiological jaundice:
a. is due to rhesus incompatibility
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b. appears in the first 24 hours after birth
c. is treated by exchange transfusion
d. is due to excessive RBC break down
e. is less common in pre term babies
77. Haemoglobin:
a. forms 80% of haemoglobin in adults.
b. consists of 2 ? & 2y chains.
c. has higer affinity for O2 than haemoglobinF.
d. contains iron in the oxidized form.
e. its amount in each red cell is 30 picogram.
78. A stained normal blood film shows:
a. 50-70% nuetrophils.
b. 4% basophils.
c. 2-8% lymphocytes.
d. 0-4% moncyted.
e. 0-0.4 % eosinophils.
79. lymphocytes:
a. forms 5-15% of lymphocytes.
b. have no nuclei.
c. produce IgM antibodies.
d. convert to plasma cell when activated.
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e. produce perforins.
80. Immunoglobulin M (IgM):
a. are called secretory immunoglobulin.
b. most abundant in the secondary immune response.
c. can cross the placenta.
d. constitutes the antibodies in the ABO blod group system.
e. consist of 4 light chains.
81. A person who is group O:
a. has both A & B antigens.
b. has both anti- A & B anti bodies.
c. act as universal reciepient.
d. can not be a father of child whose group is B.
e. his genotype is AB.
82. Acetylcholine:
a. is a steroid.
b. produced by all preganglionic autonomic fibers.
c. formation is catalized by the wnzyme choline transferase.
d. has receptors on the skeletal muscle.
e. is found normaly in the blood.
83. nor adrenaline:
a. is formed from the amino acid glycine.
b. has less affinity to alpha receptors than adrenaline.
c. is produced by the adrenal cortex.
d.is antagonized by antropine.
e. is found normaly in the blood.
84. stimulation of the parasympathetic may lead to:
a. inhibition of saliva secretion.
b. increases gastric movement.
c. dilation of the eye pupil.
d. increase blood flow to the skeletal muscle.
e. piloercetion.
85. Extracellular fluid can be measured using all the following substances except:
a. inulin.
b. mannitol.
c. sucrose.
d. evans blue.
e. radioactive thiocyanate.
86. Infustion 1 litre of 0.9% saline intravenously to a subject will immediately:
a. increased intracellular fluid volume.
b. increased extraculluer fluid volume.
c. increased both intra and extraceullar fluid volume.
d. increase urine volume.
e. increased extracellular fluid volume but decrease intracellular fluid volume.
87. if K+ concentration in ECF is increased the following may happen:
a. the resting membrane potential become less negative.
b. the resting membrane potential will not change.
c. rapid sodium channel will open.
d. an action potential will occur spontaneously.
e. the action potential will occur.
88. Which of the following substances contributes more to plasma osmolarity:
a. Na +
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b. K+
c. albumin.
d. urea.
e. glucose.
89. The following is a function of protein in the cell except;
a. water channel.
b. lons channels.
c. hormone receptors.
d. nutrition of the cell.
e. antigen.
90. which of the following can lead to oedma:
a. increase in the oncotic pressure.
b. increase in venous pressure.
c. increase in the concentration of atrial natriuretic peptide.
d. contraction of the precapillary sphincter.
e. decrease in ADH secretion.
91. Excessive loss of fluid from the body will increase:
a. bororecptors discharge.
b. chemoreceptor discharge.
c. volume recptor discharge.
d. angiotensin II formation.
e. pulse pressure.
92. What is the most highly time answer regarding the following action potential:
a. results from changes in membrane voltage .
b. obeys the principle of generator potential.
c. characterized by the fading conduction.
d. has the same amplitude in different types of nerve fibers
e. has the same form in neural fibers and myocardial fibers
93. the resting membrane potential:
a has the same magnitude in all tissues.
b. result from potassium efflux.
c. needs energy.
d. it depends on voltage gated sodium channels.
e. sodium –potassium ATPase play an important role in it.
94. Pain sensation:
a. receptors are free nerve endings.
b. is transmitted by posterior col?
c. fast pain is tramsmitted by C fibers.
d. is appreaciated in sensory cortex .
e. localization is the function of the thalamus.
95. The centers for these reflexes are as follows:
a. biceps reflex in C 5 –C6
b. plantar in S 1 –S 2.
c. ankle jerk reflex in S 1 –S 2 –S 3
d. Knee jerk reflex in L2 & L3.
e. bladder emptying reflex in L1 –L2
96. Paralysis or weakness results from:
a. upper motor neuron lesions
b. lesions of the crocipiltal brain
c. bune disease
d. lesions ofbasal ganglia
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e. lesions of cerebellum
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