MOCK – 5

1) The example of S-glycoside is

a) Sennoside b) Sinigrin c) Senegin d) Psoralen

2) Which of the following glycosides produces foam in aqueous solution?

a) Anthracene glycosides b) Saponin glycosides
c) Cardiac glycosides d) Cyanogenetic glycoside

3) The socotrine aloes mounted in lactophenol and is observed under microscope.It will
show the following character
a) Fragments composed of large number of slender prism
b) Fragments composed of large prisms grouped irregularly
c) Transparent,brown,angular or irregular fragments.
d) None of the above

4) Rutin is an example of
a) Triterpenoid glycosides b) Tropane alkaloid
c) Saponin glycoside d) Flavonoid glycoside

5) Vanillin, the active constituent of vanilla can be synthesized from :

a) Eugenol b) Carvone c) Vincristine d) Vinblastine

6) The main film-forming agent in the nail-polish is

a) Nitrocellulose b) Sulphonamide-formaldehyde
c) Ethyl lactate d) n-butyl acetate

7) The concentration of plasticizer is nail polish is:

a) 1% b) 5% c) 15% d) 25%

8) Creams are basically:

a) Semi-solids b) Emulsions
c) Ointment like preparation d) None

9) The different forms of polymorphic Cocoa Butter is all except:

a) α b) β c) βI d) αI

10) Addition of alcohol to the hydrophilic colloid leads to

a) Crystallization b) Hydration c) Precipitation d) Stabilization

11) Separation of the tablet into two or more distinct layers is

a) Picking b) Capping c) Lamination d) Broken

1 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

12) Tablets that are placed under the skin are
a) Electric coated tablets b) Film coated tablet
c) Implants d) Sublingual

13) Tablets which after oral administration release the drug at a desired time for
prolonged effect are
a) Multi compressed tablets b) Multi layer tablet
c) Enteric coated tablets d) Sustained action tablets

14) The following is filling principle in the capsule filling machine except:
a) Auger filling b) Vibratory Principle c) Dosator Principle d) Hopper filling
15) The following are the capsule imprinting machine except:
a) Hartnett b) Macofar c) Markem d) Ackley
16) The vacuum applied for the leaker test for vials is:
a) - 27 mmHg b) - 40 mmHg c) - 50 mmHg d) - 10 mmHg
17) Which of the following parental container material shows the highest Gas
permeation?
a) Polypropylene b) Polystyrene c) Polyisoprene d) Neoprene
18) Mier’s theory is associated with:
a) Heat transfer b) Super saturation c) Flow of fluid d) Flow of fluid
19) Which of the following polymer is used in a Muco-adhesive system as a bioadhesive
polymer?
a) Polymethacrylate b)Polyacrylic acid c) PEG d)Polylactate

20) which of the following statement is correct?

a) Amide Local anasthetic(LA) hydrolysed by plasma esterases
b) Amide LA long acting than ester LA
c) Dibucaine intermediate acting anasthetic
d) Both A & C
21) which of the following anticancer drug purine analogue?
a) Pentostatin b) Methotrexate c) Dacarbazine d) Carboplatin
22) which of the following drug used in diagnosis of Pheochromocytoma
a) Propranolol b) Phenoxybenzamine
c) Phentolamine d) Ergometrine

23) which pair is correct?

a) GABA- B receptor-Baclofen b) Cental α2 adrenergic-chlormezanone
c) Benzodiazepine-Tizanidine d) Both B & C
24) The risk of Digitalis toxicity is significantly increased by concomitant administration of
a) Triamterene b) Lidocaine c) Captopril d) Hydrochlorthiazide

2 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

25) The mechanism of action of Paclitaxel is
a) Bind to DNA through intercalation between specific bases and block the synthesis
of new RNA or DNA, cause DNA strand scission
b) Mitotic spindle poison through the enhancement of tubulin polymerization
c) Competitive partial agonist — inhibitor of estrogen and binds to estrogen receptors
d) S-Phase specific antimetabolite that is converted by deoxykinase to the 5’-
mononucleotide.
26) Select the specific unwanted effect of L-DOPA
a) Dementia b) Hypertension c) Dyskinesia d) Excitotoxicity
27) Caruncle is present in
a) Nutmeg b) Cardamom c) Strophanthus d) Castor
28) A liter of water-ethanol solution which contains 1.5 microliters of ethanol has
concentration of ________ ethanol.
a) 1.5 ppb b) 1.5 ppm c) 1.5 ppt d)None of these
29)In Polarography, to eliminate migration current which of following used?
a) NaC l b) KCl c) NaOH d) KOH
30)Diclofenac sodium is assayed by
a) 0.1 M NaOH b) 0.1 M TBAH
c) 0.1 M NaNO2 d) 0.1 M HClO4
31)In IR, photoconducting detector can construct from:
a)Lead sulfide b)Lead telluride
c)Mercury cadmium telluride d)All of above
32) Which reagent used for the conversion of hydrocortisone acetate to cortisone
acetate
a) CrO3 b) SeO3 c) HOBr d) m-CPBA
33) Cancergland is called?
a) Sarcoma b) Tumorous c) Carcinoma d) Leukemia
34) Which of the following is true for antineoplastics?
a) Selective toxicity to cancer cells b) Kills cells by zero-order kinetics
c)Easy access to cancer cells of any region d) Easily develop resistance
35) Which of the following is not a nitrosurea?
a) Carmustine b) Semustine
c) Estramustine d) Chlorozotocin
36) which of the following residue in DNA exists predominantly as the keto tautomer
a) Cytosine b) Guanine c) Alanine d) Thymidine
37) Which is the principle alkylator that is formed from cyclophosphamide?
a) Aldophosphmide b) 4-ketocyclophosphamide
c) 4-hydroxycyclophosphamide d) Phosphoramide mustard
38) N/10 sodium sulphide is used as a reducing agent in assay of inorganic compound
a) Iron b) Arsenic c) chlorine d) Mercury
39) Chlorinated lime is prepared by action of Cl on?
a)Calcium carbonate b) Calcium chloride
c)Calcium hydroxide d ) Calcium oxide

3 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

 40) Defficiency of which of the following causes respiratory distress syndrome?
a) Phosphetidylserine b) Sphingomyelin
c) Plasmogens d) Dipalmitoyl lecithin
41) Which of the following is not present in bark of Neem?
a) Nimbin b) Nimbidin
c) Nimbinin d) Azadirachtin
42) Which of the alkaloids are liquid and volatile in nature
a) Nicotine and Coniine b) Morphine and Paparvareine
c) Atropine and Quinine d) None of these
43) The degree of basicity of alkaloid mostly depends upon the influence caused due to
a) Electrostatic status of oxygen atom
b) Electrostatic status of carbon atom
c) Electrostatic status of sulphur atom
d) Electrostatic status of nitrogen atom
44) Herion is
a) Methyl morphine b) Diacetyl morphine
c) Butyl morphine d) None of these
45) Which drug does not contain Quinazoline alkaloid?
a) Lobelia b) Vasaka
c) Punarnava d) Shankhpushpi
46) Which of the following does not contain steroidal alkaloids?
a) Ashwagandha b) Ephedra
c) Kurchi d) Veratrum
47) Apparent volume of distribution increases when:
a) More tissue binding of drug b) More protein binding of drug
c) Both d) None
48) In biotransformation ,Phase-I reaction is also known as :
a)Conjugation b)Synthetic reaction
c)Functionalization reaction d)None of above
49) According to the pH-partition hypothesis the absorption of drug is maximum when :
a) Drug is ionized in biological fluid b)Drug is unionized in biological fluid
c) Both d)cant say
50) What effect dose plasma-protein binding have on bio-transformation?
a) Changes the mechanism b) Increases formation of metabolites
c) Slows the process d) Has no effect
51) Vanishing creams are called so because :
a) They disappear during formulation mix
b) They vanish during removal from skin surface
c) They disappear after rubbing application
d) None of the above

4 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

52) The main application of Foundation cream is :
a) To form a base for application of powders/make-up
b) To form a foundation for the formulation of Facial creams
c) To mix it with fatty acids for preparing soluble lotions
d) None of the above
53) The most frequently used surfactants in shampoos are :
a) Anionic b) Cation c) Non-ionic d) All
54) The major constituent in the After-shave is :
a) Emollient b) Anti-septics c) Alcohol d) Perfumes
55) CARBOWAX® is a type of :
a)Absorption base b)Modern ointment
c)Water soluble bases d)Oleaginous & Hydrocarbon
56) The approximate particle size of microcapsules using solvent evaporation is :
a)5-5000 µm b) 100-10,000 µm c) 10-100 µm d) 5-10 µm
57) A compound (mol. Wt – 200gm/mol) has specific absorbance 100 at its λ = 257.Find
mola absorptivity of compound.
a) 200 b) 2000 c) 1000 d) 100
58) PMR of 2-methyl 1-pentene gives how many peaks?
a)3 b) 4 c) 5 d) 6
59) Presence of Si in TMS cause
a)Deshielding and upfield b)Deshielding and downfield
c)Shielding and upfield d)Shielding and downfield
60) Value of λmax for a particular compound is
a) Increase with increase in concentration
b) Decrease with decrease in concentration
c) Does not change
d) Both of a & b
61) IP assay of Ferrous gluconate tablet is carried out by
a) Ceriometry b) Iodometry
c) Iodimetry d) Argentometry
62) Precision is calculated by
a) Standard deviation b) Mean c) Mode d) Median
63) Nernst equation used to measure
a) Current b) Conductance c) Potential d) Resistance
64) Transmittance is defined as
a) Log I0/It b) Log It/I0 c) It/I0 d) I0/It
65) Which indicator is not used for weak base and strong acid titration ?
a) Methyl orange b) Methyl red
c) Bromocresol green d) Thymol blue

5 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

66) A conductivity cell consists of
a) Two platinised-platinum electrodes
b) A platinum-calomel electrode system
c) A platinum-tungsten electrode system
d) A glass-calomel electrode system

67) Polarogram of a solution containing an electro-reducible substance is obtained by

plotting
a) Current Vs Volume b) Current Vs Potential
c) Resistance Vs Time d) Potential Vs Volume
68) Paracetamol is assayed by
a)Ceric ammonium sulphate b) I2
b)HPLC d)KIO3
69) Which of following used as precipitating agent for Ca2+ ion in gravimetry analysis?
a)BaCl2 b)HNO3
c)NH4SCN d)H2C2O4
70) In Polarography, diffusion current indicate
a)Quality of compound b)Quantity of compound
c)Both of above d)None of above
71) Assay of Furosemide is carried out by
a)Back titration with NaOH b)Direct titration with NaOH
c)Back titration with HCl d)Direct titration with HCl
72) In Polarography, apparatus used is
a)Polarogram b)Polarograph
c)Polarometer d)Polaroscope
73) Ascorbic acid injection assayed by
a)CAS b)2,6- dichloro indophenol
c)I2 d)KIO3
74) Kjeldahl method is used for
a)Hydrogen estimation b)Sulfur estimation
c)Nitrogen estimation d)All of above
75) Which of following used as indicator in Non-aqueous titration?
a)Crystal violet b)Quinaldine red
c)Orcet blue d)All of above
76) Assay of the chloride ion in intraperitoneal dialysis fluid is carried out by :
a)Complexometric titration b)Gravimetric method
c)Mohr’s method d)Karl fischer titration
77) How many gm of NaOH required to prepare 100 ml 1 M solution of NaOH?
a)400 mg b)4 gm
c)200 mg d)2 gm

6 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

78) What is the λmax for the following compound? Use the above parameters for
your calculation.

a) 229 nm
b) 249 nm
c) 254 nm
d) 259 nm
79) Specific conductance(conductivity ‘k’) unit is
a)Ohm cm-1 b)Mho cm-1
c)Ohm cm d)Ohm-1 cm-2
80) Ammonium purpurate(murexide) is used for determination of
a)Sodium b)Calcium
c)Silver d)Iron
81) Which of following primary standard used to standardize Perchloric acid
a)Potassium hydrogen phthalate b)Sodium carbonate
c)KBr d)Oxalic acid
82) What is the reagent used for diazotization?
a)NaNO2 + dilute HCI b)KNO3 + dilute H2S04
c)Zn + dilute H2S04 d)Tin + H2S04
83) IP assay of Al(OH)3 is carried out by using disodium edetate, which of following
method is used for this complexometric titration?
a) Direct titration b)Back titration
c)Replacement titration d)None of above
84) Karl Fischer reagent is standardized against
a)Sodium acetate b)Sodium tartrate
c)Disodium edentate d)Potassium acetate
85) The phase III clinical trials are performed
a) As multicenter trials on 1000-3000 of normal healthy volunteers
b) As multicenter trials on 100-300 of normal healthy volunteers
c) As multicenter trials on 1000-3000 of patient
d) As multicenter trials on 100-300 of patient
86) Which of the following drugs is/are used in status epilepticus
a) Benzodiazepine b)Phenytoin
c) Thiopentone and propofol d) All of the above
87) Which of the following is/ are excitatory neurotransmitter
a) Acetylcholine b) Glutamate c) Aspartate d) Both A and B

7 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

88) The inverse agonist of benzodiazepine is
a) Biculline b) Muscimol c) Flumazenil d) All of above
89) which steroid anaesthetic act on modulatory site of GABA-A receptor?
a) flumazenil b)muscimol c)bicuculine d)alphaxolone
90)which drug act by free radical scavenger like action for ischaemic braine damage?
a)riluzol b)lobeluzole c)tirilazad d)clormethiazole
91)all anaesthetic agent depress respiration system except,
a)nitrous oxide b)sevoflurene c)halothane d)desflurene
92) which benzodiazepine undergo direct glucoride formation?
a)chlordiazepoxide b)midazolam c)triazolam d)lorazepam
93) Isoflurane & enflurane are:
a) Structural isomers b) Enantiomers c)Diastereomers d) Optical isomers
94) Benzodiazepine binding site on GABA receptor is:
a) Near Cl- channel b)Inside the channel
c) Outside the channel d) On the alpha subunit
95) Hyperkalaemia with suxamethonium is associated with
a) Myotonic dystrophy b) Parkinson's disease
c) Meningomyelocoele d) Cerebral palsy
96) which antipsychotic drug cause T- wave abnormality?
a)clozapine b)quatipine
c)thioridazone d)sulpiride
97) which antiepileptic agent inhibit carbonic anhydrase?
a)topiramate b)felbamate
c)lamotrigine d)vigabatrine
98) Which antidepressant drug act through α1 blocking?
a)trazodone b)maprotiline
c)bupropion d)mirtazapine
99) From following which is related to straub phenomena?
a)GABA b)amphetamine
c)morphine d)ethanol
100) Choose one appropriate therapeutic use for imipramine.
a) Insomnia b) Epilepsy
c) Bed wetting in children d) Mania
101) An anticholinesterase which is useful in Alzheimer’s disease is
a) Arecolin b) Donepezil
c) Isoproterenol d)Clioquinol
102) The action of nondepolarising neuromuscular blocking agents is PROLONGED by:
a) Respiratory acidosis b) Increased temperature
c) Increased calcium d) Increased potassium
103) A young man suffered from generalized anxiety which drug is preferred?
a) zolpidem b) buspiron
c) midazolam d) triazolam

8 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

104) Alkaloids in cinchona bark are determine by
a) Nesseler’s reagent b) Iodine test
c) Thalloquin test d)Wagner’s test
105) In which Ayurvedic formulation preservative is not required
a)Lepa b) Vatika
c) Asava d) Pisti
106) Who is the “father of medicine”?
a) Aristotal b) Hippocrates
c) Galen d) William withering
107) The term ‘siddha’ means
a) Bhakti b) Yoga
c) Acheivement d) Body
108) Which polysaccharide soluble in water ?
a) Cellulose b) Inulin
c) Lactose d) Starch
109) According to ayurveda PITA (bile) is responsible for :-
a) transmitting sense impression to the min
b)providing the static energy for holding body tissue together
c) all digestive and metabolic activities
d)lubrication of various points of friction
110) Chinese rhapontic rhubarb can be distinguished from Indian rhubarb by florescence
Developed in U.V. light which is
a) deep yellow b) deep violet c) green d) blue
111) Panchmahabhuta and Tridosha theory is related to
a) Homoeopathy b) Aroma therapy
c) Unani system d) Ayurveda
112) The moisture content is determined by heating a drug at______0c to at constant weight.
a) 105 b)110 c) 120 d) 320
113) Bromelin use in inflammation which is obtained from
a) apple b) pineapple c) banana d) thornapple
114) Chlorophytum borivillianum used as
a) Anti-fertility b) Aphrodisiac
c) Anti-pyretic d) Expectorant
115) Which flavonoids present in mulethi ?
a) Liquiritin b) Isoliquiritin
c) Both a&b d) None of the above
116) Which of the following drug has antidiabetic activity ?
a) Brahmi b) Shatavari
c) Momordica d) Liquorice
117) Chikusetusaponin present in
a) Liquorice b) Ginseng
c) Senega d) Quillaia

9 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

118) Potassium myronate (sinigrin) after hydrolysis in presence of myrosin yields
a) Allyl isothiocyanate b) Allyl thiocyanate
c) Allyl isocyanate d) Amygdalin
119) The word ‘ayurveda’ means :-
a) health of people b) science of drugs
c) science of life d) none of the above
120) The loading dose (DL) of a drug is usually based on the
a) Total body clearance (CIT) of the drug
b) Percentage of drug bound to plasma protein
c) Apparent volume of distribution (VD) and desired drug concentration in plasma
d) Area under the plasma drug concentration versus time curve (AUC)
121) The plasticizer normally used in the nail polish are :
a) Di-butyl stearate b) Di-butyl phthalate.
c) Nitro cellulose d) Both a & b
122) The function of Brilliantine is to :
a) To hold the hair in position & make them lustrous
b) As a hair remover
c) As a lubricant in hair oil
d) None
123) Lakes are :
a)Natural lubricants b) Diluents
c)Dyes & Colorants d) Sugar Coating solutions
124) Which tooling used in case of large tablet
a) B tooling b) BB tooling
c) D tooling d) all
125) One of the following is NOT used in the Shampoo.Identify.
a) Sequestrants b) Preservatives
c) Thickening agents d) Dileunts
126) Bromo mixture is used in the Lipsticks to :
a) To solubilize the fatty acids b) As a preservative
c) As a colorant d) As a perfume
127) Type 2 glass is made up of
a) Highly resistant borosilicate glass b) Highly resistant soda lime.
c) Moderately resistant soda lime d) Moderately resistant borosilicate
128) Omeprazole has volume of distribution 90 Ltrs when it is given in 30 mg dose. What
is the plasma concentration Omeprazole at particular time ?
a) 3.33 µg/ml b) 0.33 µg/ml c) 33.3 µg/ml d) 3.0 µg/ml
129) The size reduction by impact is achieved in
a) Ball mill b) Edge Runner mill
c) End Runner mill d) Hammer mill

10 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

130) ALZET formulation is a kind of a:
a) Vapor pressure pump b) Osmotic pump
c) Battery driven pump d)None
131) Give the correct relation
a)1 atm = 1/760 mm of Hg = 1 torr b) 1 atm = 760 mm of Hg = 1 torr
c)1 atm = 760 mm of Hg = 760 torr. d) 1 atm = 1/760 mm of Hg = 1/760 torr
132) Which of the following schedule is for Standards for surgical dressing ??
a)FF b) E c) F2. d) F
133) Which of the following drugs belongs to schedule X
a) Phenobarbitone b) Diazepam
c) Chloramphenicol d)Theophyline
134) What quantities of 95% v/v & 45% v/v alcohol are to be mixed to make 800ml of
65%v/v alcohol?
a) 480 ml of 95% & 320 ml of 45% alcohol
b) 320 ml of 95% & 480 ml of 45% alcohol
c) 440 ml of 95% & 360 ml of 45% alcohol
d) 360 ml of 95% & 440ml of 45% alcohol
135) Which of the following is not an ideal requirement for suppository ?
a) It should melt at body temperature
b) Compatible with large variety of drug
c)It should have metastable form.
d) Melting point and solidification point should be close
136) Multidose injections are packed in
a) Vials b) Ampoules
c) Infusion bottles d) Disposable sets
137) Which one of the following is commonly used as preservative in eye-drops
a) Propyl paraben b) Butylated hydroxyl toluene
c) Phenol d) Benzalkonium chloride
138) Theobroma oil is a type of ________ suppository base.
a) Oleagenious b) Hydrophillic
c) Emulsifying d) None
139) Witepsol is a type of :
a) Aqueous base b) Emulsifying base
c) Oleogenous base d) None
140) A drug X has a molecular weight of 750 daltons.From which of the following route
will it get excreted?
a)Biliary excretion b)Urinary excretion c)Both d)Can’t say

141) Flip-flop phenomenon occurs when :

a)Ka/ke ≥ 3 b)Ke/Ka ≥ 3 c)Ka=Ke d) None

11 PHARMAGLIMPS-A GLIMPSE OF PHARMACY

142) The biological half-life of procaine in a patient was 35 mins & its Vd was estimated
to be 60 liter.The total clearance rate of procaine is :
a)1.88 lit/min b)0.115 lit/min c)11.5 lit/min d)5.57 lit/min
143) Which test is performed for the diagnosis of Typhoid ?
a) Dick test b) Widal test c) Tine test d) Schik test
144) The following are the types of encapsulation technique except:
a) Air Suspension b) Pan coating
c) Spray drying-congealing d) Compression coating
145) Class 100 area utilised in aseptic filling of Parentral,which means
a) not more than 100 particles of ≥0.5 µm in one cubic meter
b) not more than 100 particles of ≥0.5 µm in one cubic foot
c) not more than 100 particles of >0.5 µm in one cubic meter
d) not more than 100 particles of >0.5 µm in one cubic foot
146) DOP test is performed for measurement of efficiency of HEPA filter, anemometer is
used with it for which reason
a) to measure particle size b) to measure velocity of air
c) to measure pore size of HEPA filter d) none
147) As per GMP permitted limit of solud contants in water for injection is :
a) 100 ppm b) 1.0ppm c)0.1 ppm d)10.0ppm
148) The amount of fatty substances in Shaving creams is :
a) 20% b) 30% c) 45% d) 15%
149) Depilatories are substances which :
a) Removes hair without removing skin
b) Moisturizes the skin
c) Imparts color to the hair
d) Are used to held the hair in the position
150) The following combination of dye-color are true except:
a) Amaranth-Red
b) Indigo Carmine- Blue
c) Tartrazine-Yellow
d) Erythrosine-Blue

12 PHARMAGLIMPS-A GLIMPSE OF PHARMACY