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Chapter2 WPS Office

Sleep plays a key role in maintaining various bodily systems and processes related to health and longevity. Lack of sleep can negatively impact cognitive functioning, with short sleep associated with cognitive deficits. Epidemiological data also links less than 5 hours of sleep per night to a twofold increased risk of dementia, while experimental studies show sleep deprivation increases amyloid plaques and tau tangles in the brain. Acute and chronic sleep deprivation in animals has been shown to impair memory and synaptic plasticity in the hippocampus. The mechanisms by which sleep deprivation affects cognitive function require further investigation.

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46 views17 pages

Chapter2 WPS Office

Sleep plays a key role in maintaining various bodily systems and processes related to health and longevity. Lack of sleep can negatively impact cognitive functioning, with short sleep associated with cognitive deficits. Epidemiological data also links less than 5 hours of sleep per night to a twofold increased risk of dementia, while experimental studies show sleep deprivation increases amyloid plaques and tau tangles in the brain. Acute and chronic sleep deprivation in animals has been shown to impair memory and synaptic plasticity in the hippocampus. The mechanisms by which sleep deprivation affects cognitive function require further investigation.

Uploaded by

Maria alexa Gonzales
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Chapter 1

Introduction

Sleep plays a necessary role in maintaining the homeostasis of the immune , metabolic ,
gastrointestinal , cardiovascular , and central nervous systems which supports that sleep is essential to
human health and longevity Krueger et al..2016, Medic et al..2017, Tobaldini et al..2019 First-rank
Cognitive functioning is dependent on good Sleep.Accumulating clinical and experimental studies
indicate that Sleep loss can result in cognitive deficits (Krause et al 2017 , Shi et al 2018 Short and Chee,
2019)Epidemiologic data also Shows that Sleeping time 5h prospecticvely predicts a twofold increase in
incident dementia (Robbins et al 2021) Experimental SD in humans and animals has been confirmed to
increase amyloid burden and tau aggregation which are linked with the development and progression of
Alzheimers disease ( AD) (Chen et al 2017 , Holth et al 2019 ,Kang et al 2021) and basic studies done
with mice have shown that acute SD leads to.long-term spatial reference memory impairment of
chronic SD can cause impairment of working memory and dysregulation of synaptic plasticity , and
even hippocampal shrinkage (Kreutzmann et al 2015 , Wadhwa et al 2019 , yin al 2017) Although
countless facts demonstrate that sleep problems are risk factors for the development of mild cognitive
impairment , preclinical AD, and AD, the mechanisms underlying the disruption of SD on cognitive
functiion need to be further ecavated.

Hwang and golbay 2012 it is unclear whether this prefrontal activation reflects episodic memory
function the organization of information in warking memory or the executive control of attention and
memory., based on the information provided, it is difficult to form a definitive opinion on whether the
prefrontal activation observed in hwang and Golbays 2012 study reflects episodic memory function, the
organization of information in working memory, or the executive control of attention and
memory.,Achermann 2012) the homeostatic process S depends on sleep and wakefulness the need for
sleep increases as wakefulness continues the theory for circadian process C suggests a control of an
endogenous circardian pacemaker, which affects thresholds for the on set and offset of a sleep episode
the interaction of these two processes determines the sleep i wake cycle and can be used to describe
fluctuations in alertness and vigilance. ,the idea that the need for sleep increases as wakefulness
continues is consistent which refers to the bodys ability to maintain a atable internal environment. The
accumulation of sleep bebt over time results in a increased need for sleep, which ultimately leads to the
onset of a sleep episode.

Reduced attention and focus sleep deprivation. can lead to a decrease in attention and focus making it
harder to concentrate on tasks and make sound decisions.,Impaired memory consolidation lack of sleep
can impact the ability to form and consolidate memories, which can lead to difficulties in recalling
important information ., slower reactiontime sleep deprived individuals may have slower reaction
times,which can be dangerours in situations that require quick reflexes,such as driving.,Poor problem-
solving skills sleep deprivation can also affect problem-solving skills,making it harder to think critically
and come up with effective solutions.,Increased risk -taking behavior studies have shown that sleep
deprivation can lead to increased risk-taking behavior ,as the brain may be less able to evalute potential
consequences of actions.

Reduced attention and focus are common Symptoms of sleep deprivation which occurs when an
ldividual does not get enough sleep .Sleep deprivation can affecta persons ability to concentrate on
tasks ,leading to reduced productivity and decsion making abilities.,Establish a consistent sleep schedule
by going to bed and waking up at the same time every day,including weekends.,Get enough sleep the
most obvious solution is to ensure that individuals get enough sleep on avetage adults need 7-9 hours of
sleep per night getting enought sleep helps to improve reaction time and conitive function.,Sleep
deprivation can have a hsignificant impact on problem-solving skills.when we dont get enough sleep our
cognitive abilities are impaired and our ability to think critically and creatively is reduced.,The problem
statement is shown that when individuls are sleep deprived they may be less able to evalute ponlential
concequences of their actions leading to incrcased risk-taking behavior.

This Study Claims that Sleep deprivation Shown to have a Significant impact on Cognitive Function in
Chuding Cognitive development there are numerous research papers that have investigated the
relationship between Sleep deprivation and Cogmtive lf you are Concerned about your own Sleep nabits
or those of a loved one its Important to Speak with a healthcare provider Who Can provide

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