1 - GS200 Service Manual
1 - GS200 Service Manual
Model: GS200
Service Manual
For In Vitro Diagnostic Use
Intellectual Property
Genrui Biotech Inc. (hereinafter called Genrui) owns the copyright to this unpublished
manual and intends to maintain it as confidential. This publication is to be used solely for
the purposes of reference for Genrui equipment.
Genrui owns this manual and all intellectual property rights (including copyright) in this
manual. Nobody is allowed to use, disclose or let others obtain part or whole information
of this manual in any manner whatsoever without the written permission of Genrui.
Nobody is allowed to take the following actions to part or all contents of this manual,
including (but not limited to) shoot, reproduce, copy, or translate it into other languages
without the written permission of Genrui.
Genrui reserves the right to modify the content of this manual without prior notice.
Genrui reserves the right to make technical alterations without prior notice.
Genrui reserves the right to change the product specifications without prior notice.
Statement
Regarding this manual, Genrui will not take any warranty responsibility, expressed or
implied, including (but not limited to) warranties of merchantability and fitness for any
particular purpose.
Genrui is responsible for safety, reliability and performance of this equipment only in the
conditions that:
Genrui will not take the responsibility for the products’ safety, reliability and performance
based on the following situations:
Warranty
Maintenance service
Where the equipments conform to the provisions of Genrui Warranty Services Ordinance
I
range can enjoy the free service.
Services to be charged
(1) Services not included in Genrui Warranty Services Ordinance range should be
charged by Genrui.
(2) Damages caused by the following reasons should be charged for the services, even in
warranty period:
Man-made damage
Genrui will not be responsible for the direct, indirect or eventual damages and delays
resulting from the following conditions (including but not limited to):
Website: www.genrui-bio.com
II
Introduction
The following sections introduce the warning symbols used on the analyzer. Ignorance of
these symbols may get you into the risks of death or injury. The symbols are listed in a
1. Safety Precautions
ELECTRIC SHOCK
(1) When the main power is ON, the panels, side cover or rear cover of
the analyzer are not allowed to be opened unless by qualified personnel.
(2) Please make sure that no liquid spillage spatters on the panels. In
case liquid goes inside analyzer, just turn off the power supply and contact
manufacturer as soon as possible.
(3) There is high pressure in the interior of the computer and printer, do
not touch the interior of them.
PERSONAL INJURY
1 The sharp components of the analyzer can cause puncture wounds. To
prevent injury, please exercise caution when working around the reagent
probe, sample probe, mixer, auto-wash system etc.
2 When the analyzer is in operation, do not touch such moving parts as
sample probe, reagent probe, mixer, auto-wash system, fan, etc.
HIGH TEMPERATURE
1 Before replacing the lamp, please switch off the main power and then wait
at least 30 minutes till the lamp cooling down.
2 Do not touch the print head or the metal part near it; otherwise you may
get burned.
STRONG LIGHT
The light transmitted by the lamp may hurt your eyes. Do not stare at the lamp
when the system is in operation.
III
Introduction
BIOHAZARD
1 All test samples, such as calibrator and control, are infectious. If
necessary, please wear gloves when working with these samples.
2 All waste liquids should be considered infectious. Please wear gloves
when working with waste liquids.
3 Those components that have been attached with the reagent probe,
sample probe, mixer, waste tube and waste tank are infectious. Please
wear gloves when working with them.
CORROSION
1 The wash solution and certain reagents are strongly acid or alkaline.
While using them, exercise caution and prevent direct contact with your
hands or clothes. In case your hands or clothes contact the wash solution
or reagents, wash them off immediately with soap and clean water.
2 In case they spill into your eyes, rinse them with much water and consult
an oculist.
FLAMABILITY
Do not use flammable substances around the system, such as alcohol and
ether.
EXPLOSION
Do not use explosive substances around the system.
2. Precautions on Use
INTENDED USE
1 The analyzer mainly used in medical institutions to do the biochemical
tests of samples from human body, such as serum, plasma and urine.
2 To draw a clinical conclusion, please also refer to the patient’s clinical
symptoms and other test results.
OPERATOR
The analyzer is to be operated only by personnel trained and authorized by
manufacturer or authorized distributors.
ENVIRONMENT
1 Please install and operate the system in an environment specified by this
manual. Installing and operating the system in other environment may lead
to unreliable results and even equipment damage.
2 To relocate the system, please contact manufacturer or your local distributor.
ELECTROMAGNETIC NOISE
1 Electromagnetic noise may interfere with operations of the system, or even
lead to unreliable test results and misoperation. Do not use such devices
as electric drill, mobile phones or radio interphones near the system.
IV
Contents
2 The system may generate electromagnetic wave during operation. Do not install or
use electrosensitive equipment near the system.
GROUNDING
1 Make sure the power socket is grounded correctly. Improper grounding may lead to
electric shock.
2 The grounding resistance must be lower than 10mΩ. Improper grounding may lead to
unreliable test results and risk of enclosure leakage and even electric shock.
LIQUID LEAKAGE
1 Please check the tubing connectors carefully before starting tests. Leakage may
cause inaccurate aspiration or dispensing.
2 Do not place reagents or samples on the panels of the analyzer; otherwise liquid
spray or leakage may occur.
PROBE BLOCKAGE
Check the reagents and samples carefully for insoluble matters, such as fibrin and
protein; otherwise the reagent probe or sample probe may be blocked.
WATER
The water used should meet the requirements of the CAP Type II, otherwise it may lead to
valve and pump damage easily, and the cleaning is not clean, etc.
SYSTEM USE
1 Operate the system strictly as instructed by this manual. Inappropriate use of the
system may lead to unreliable test results or even equipment damage or personal
injury.
2 Before using the system for the first time, run the calibration program and QC program
to make sure the analyzer is in proper state.
3 Be sure to run the QC program every time you use the system, otherwise the result
may be unreliable.
4 Do not open the cover of the reaction disk when the analyzer is in operation
5 Please install the reaction disk cover, reagent/sample disk cover before start the
analyzing.
6 Be sure that there is no obstacle in the moving paths of the probe and mixer during
analyzing
7 For safety, please don’t touch the reaction disk or reagent/sample disk when it is in
operation.
8 The operating software installed on the operation unit is specified by manufacturer.
Please do not install any other software or hardware, otherwise it may affect the
system. .Do not run other software when the system is in operation.
V
Introduction
9 Do not use this computer for other purposes. Inappropriate use of it will probably
introduce computer virus, which may spread through floppy disks, software or
network, into the system.
SYSTEM MAINTENANCE
1 Maintain the system strictly as instructed by this manual. Inappropriate maintenance
may lead to unreliable results or equipment damage or personal injury.
2 Replacement of such major parts as photometer, probe, mixing bar and syringe
plunger assembly must be followed by a calibration.
3 In allusion to the characteristics of high temperature, low humidity and extreme
dryness which exceed the design requirements of the working environment of the
South Asia countries (including India, Pakistan, Bengal, and Sri Lanka), it should add
the maintenance of dusting and adding lubricating grease regularly.
4 In the case that the analyzer discontinue use because of error or other reason and
needs repair or disposal, please contact manufacturer, meanwhile
Please take other measures to avoid delay in results, for example, use other
machines or other methods to continue to finish the test.
Please dispose of the used cuvette in compliance with the local regulations.
Wear gloves while disposing of the used cuvette to avoid biohazard.
Take out the reagent bottle in the analyzer and store it in accordance with the
reagent kit. For example, put the reagent back in the refrigerator to keep it from
spoilage.
SAMPLES
1 Use serum samples that are completely separated from blood clots or urine samples
that are free from suspended matter. If fibrin exists in the serum samples or
suspended matter exists in the urine samples, the probe may be blocked.
2 Medicines, anticoagulants or preservative in the samples may lead to unreliable
results.
3 Hemolysis, jaundice or chylomicron in the samples may lead to unreliable test results.
Sample blank analysis is recommended.
4 Store the samples properly. Improper storage may change the compositions of the
samples and lead to unreliable results.
5 Sample volatilization may lead to unreliable results. Do not leave the sample open for
a long period.
6 The system has a specific requirement on the sample volume. Refer to this manual for
proper sample volume.
7 Load the sample to proper tube position on the sample disk before the analysis
begins; otherwise you will not obtain correct results.
VI
Contents
about your reagent choice.
3 Store and use the reagents, calibrators and controls strictly as instructed by the
suppliers. Otherwise, you may not obtain reliable results or best performance of the
system.
4 If the storage of the reagents, calibrators and controls is improper, it may lead to
unreliable test results even if it is within the validity period.
5 Perform calibration after changing the reagents. Otherwise, you may not obtain
reliable results.
6 Cross-contamination among reagents may lead to unreliable test results. Consult the
reagent suppliers for details.
CUVETTE USE LIFE
1 The replacement cycle for the semi-permanent cuvette is 3 months. Please replace
the cuvette according to method of replacing cuvettes in operation manual when the
cuvette is used for more than 3 months.
2 Please use only the wash solution supplied by manufacturer to wash cuvettes,
Otherwise, you may not obtain expected results.
3. The wash solution supplied by manufacturer is WASH DILUTION
PARAMETERS
Incorrect analysis parameters may cause erroneous test results. Please consult
manufacturer or your reagent supplier for correct parameters.
DATA BACKUP
The system can store data to the hard disk of the PC automatically. However, data loss is
still possible due to deletion or physical damage of the hard disk. We recommend you to
back up the data to portable storage device regularly.
DISPOSING OF ANALYZER
Some materials of the analyzer are subject to contamination regulations. Dispose of the
analyzer in accordance with your local or national guidelines for waste disposal.
Foreword
In order to use the product correctly, please read this manual carefully. After reading,
please keep it properly for future use.
VII
Introduction
Contents
IX
Chapter 1 System Specification
Minimum 160μL
Reaction
Volume
Operating
Windows 7/10
System
Save the data automatically and can save various kinds of data for
Data Storage
more than 5 years.
1
Chapter 1 System Specification
Sample/reagent
barcode Scan and read the sample/reagent barcode.
scanner
Temperature 0℃ ~40℃
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Chapter 2 Installation and Update
inspect the apparatus carefully when you receive it before opening the box to make sure
whether there are the following damages or not:
(1) The external packaging is with inversion or deformation.
(2) The external packaging is marked with wet water evidently.
(3) The external packaging is with evident trace of hit.
(4) The external packaging is with sign of being opened.
When you find the above damages, inform the local agent as soon as possible.
If the external packaging is proper, open the box and inspect the apparatus with no
absence of the agent and staff of manufacturer.
(1) Make sure that all the components are complete according to the packing list.
(2) Inspect the exterior of the components carefully to make sure whether there are
cracks, bruises or deformations or not.
The bearing ground should be level with gradient less than 1/200. It should
be hard enough to bear weight about 250kgs.
Installation site The installation site should be free of dust, corrosive and flammable gas, no
heat and wind source, neither mechanical vibration.
It shall not be exposed in sunshine directly and should be well ventilated.
Space
Environment
10℃ - 30℃
Temperature
Relative
30%-70%, away from dew.
humidity
Atmospheric
86.0 kPa-106.0kPa
pressure
Ventilation Well-ventilated to the outside with the analyzer not exposed directly to the
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Chapter 2 Installation and Update
wind source.
Otherwise, please connect a copper wire with resistance below 10mΩ to the
rear cover screw of the analyzer and bury the other end of the copper wire
into the earth.
Electromagnetic Away from brush-type motors and electrical-contacts equipments which are
wave powered on and off frequently.
3. If the water purification equipment is used, the analyzer can only use gravity-type
water.
4. The distance between the water supply device and the water inlet of the analyzer
must be less than 10m.
5. Length of the waste tubing connected to the analyzer must less than 2m.
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Chapter 2 Installation and Update
Biohazard
Please dispose the waste liquid compliantly with the local regulation.
NOTE
The water must meet the water standard requirement of CAP II.
2. Put purified water float detector into the purified water bucket and then connect the
connector of the purified water detector assembly to the connector of the purified
water detector which is on the left side or back side of the analyzer.
Biohazard
Please dispose the waste liquid compliantly with the local regulation.
NOTE
The purified water bucket must be placed around the analyzer to ensure
that the purified water inlet tube can absorb the water at the bottom of the
bucket.
instrument, the other end insert into the waste bucket, leave proper length and cut
the waste tube. For analyzers with auto washing unit, there will be 2 waste tubes
and 2 waste outlets at the backside the analyzer, please connect both.
2. Connect waste detector line with the waste detector connector, put the waste
detector into waste container as a cap of it.
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Chapter 2 Installation and Update
3. Insert the end of the waste tube into the hole on the cap as shown in below figure.
For analyzers with auto washing unit, there will be 2 waste tubes, please connect
both.
BIOHAZARD
Wear gloves and lab coat and, if necessary, goggles.
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Chapter 2 Installation and Update
1 Connect one end of the power cord to the power input of the analyzer and the
other end to the power supply.
2 Power supply requirements: AC 100~240V,50/60Hz±1Hz.
1 Connect one end of the serial port wire to the serial port of the analyzer and the
other end to the serial port of the computer.
2 Do mind that the communication lines and the AC power cord cannot be bond
together.
2.8 Debugging
Before checking, please put 10 sets of new reaction cuvette in to reaction disk, put
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Chapter 2 Installation and Update
For the vertical parameters, for example, the current parameter is 30, if increase the
value to 37, the probe will go lower 7 steps.
For counterclockwise rotary parameters, for example, the current parameter is 4, if
increase the value to 6, the probe will go right 2 steps; if decrease the value to 1, the
probe will go left 3 steps.
For sample probe, rotation parameters including:
1. Reaction Disk add R1 Position
2. Reaction Disk add R2 Position
3. Acid/Alkaline Wash Solution Position
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Chapter 2 Installation and Update
If the probe in any of these positions are not in center, please adjust its parameters, the
detail procedure is listed below.
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Chapter 2 Installation and Update
Step 2
Select “Rotate to Reaction Disk Adding R1 position” command, then “Execute Command”.
Step 3
Select “Lower specified steps”, input value “10”, then “Execute Command”.
Probe will be above No. 1 cuvette position, repeat sending this command until the probe
reach the surface of the cuvette so that you can observe easier.
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Chapter 2 Installation and Update
Left Right
Step 4
1) If the probe is on the left of No. 1 cuvette center, plus 1 or 2 in “Configuration
Parameters for Rotating Counterclockwise to Reaction Disk R1 position”
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Chapter 2 Installation and Update
Step 5
Select “Vertical Reset”, then “Execute Command”.
Step 6
Select “Rotary Reset”, then “Execute Command”.
Step 7
Click “Save configuration” button to save the parameter.
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Chapter 2 Installation and Update
Step 2
Select “Rotate to Reaction Disk Adding R2/S position”, then “Execute Command”.
Step 3
Select “Lower specified steps”, input value “10”, then “Execute Command”.
Probe will be above No. 42 cuvette position, repeat sending this command until the probe
reach the surface of the cuvette so that you can observe easier.
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Chapter 2 Installation and Update
Left Right
Step 4
1) If the probe is on the left of No. 42 cuvette center, plus 1 or 2 in “ Configuration
Parameters for Rotating Counterclockwise to Reaction Disk R2/S position”
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Chapter 2 Installation and Update
Step 5
Select “Vertical Reset”, then “Execute Command”.
Step 6
Select “Rotary Reset”, then “Execute Command”.
Step 7
Click “Save configuration” button to save the parameter.
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Chapter 2 Installation and Update
Step 2
Select “Lower specified steps”, input value “10”, then “Execute Command”. Repeat
sending this command until you can observe easier.
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Chapter 2 Installation and Update
Left Right
Step 3
1) If the probe is on the left of bottle, plus 1 or 2 in “Configuration Parameters for Rotating
Counterclockwise to Wash Solution Position”
2) If the probe is on the Right of bottle, minus 1 or 2 in “Configuration Parameters for
Rotating Counterclockwise to Wash Solution Position”
Step 4
Select “Vertical Reset”, then “Execute Command”.
Step5
Select “Rotary Reset”, then “Execute Command”.
Repeat Step 1- 5 until the probe position is in the center of the bottle
(Attention: that will be ok if the probe doesn’t collide, you don’t have to make it 100%
center)
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Chapter 2 Installation and Update
Step 1
Select “Rotate to Reaction Disk Adding R1 Position”, then “Execute Command”.
Step 2
Select “Rotate to Wash Well”, then “Execute Command”.
Step 3
Select “Lower specified steps”, input value “10”, then “Execute Command”. Repeat
sending this command until you can observe easier.
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Chapter 2 Installation and Update
Left Right
1) If the probe is on the left of wash well, plus 1 or 2 in “Configuration Parameters for
Rotating Counterclockwise to Wash Well”
2) If the probe is on the Right side of wash well, minus 1 or 2 in “Configuration Parameters
for Rotating Counterclockwise to Wash Well”
Then Click “Effectuate configuration” buttons.
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Chapter 2 Installation and Update
Step 4
Select “Vertical Reset”, then “Execute Command”.
Step 5
Select “Rotary Reset”, then “Execute Command”.
Repeat Step 2- 5 until the probe position is in the center of the wash well
(Attention: it will be ok if the probe doesn’t collide, no need to make it 100% center)
Step 6
Click “Save Configuration” button to save the parameter.
Step2
Select “Rotate to Sample Position”, then “Execute Command”.
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Chapter 2 Installation and Update
Step 3
Select “Lower specified steps”, input value “10”, then “Execute Command”. Repeat
sending this command until you can observe easier.
Left Right
1) If the probe is on the left of wash well, plus 1 or 2 in “Configuration Parameters for
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Chapter 2 Installation and Update
Step4
Select “Vertical Reset”, then “Execute Command”.
Step5
Select “Rotary Reset”, then “Execute Command”.
Repeat Step 2- 5 until the probe is in the center of the reagent bottle
(Attention: it will be ok if the probe doesn’t collide, no need to make it 100% center)
Step 6
Click “Save Configuration” button to save the parameter.
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Chapter 2 Installation and Update
Step 2
Select “Rotate to Reagent Position”, input “2”, then “Execute Command”, send.
Step 3
Select “Lower specified steps”, input value “10”, then “Execute Command”. Repeat
sending this command until you can observe easier.
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Chapter 2 Installation and Update
Left Right
1) If the probe is on the left of wash well, plus 1 or 2 in “Configuration Parameters for
Rotating Counterclockwise to Outer Ring Reagent Position”
2) If the probe is on the Right of wash well, minus 1 or 2 in “Configuration Parameters for
Rotating Counterclockwise to Outer Ring Reagent Position”
Step 4
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Chapter 2 Installation and Update
Step 5
Select “Rotary Reset”, then “Execute Command”.
Repeat Step 2- 5 until the probe is in the center of the reagent bottle
(Attention: it will be ok if the probe doesn’t collide, no need to make it 100% center)
Step 6
Click “Save Configuration” button to save the parameter.
Step 2
Select “Rotate to Reagent Position”, input “1”, then “Execute Command”.
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Chapter 2 Installation and Update
Step 3
Select “Lower specified steps”, input value “10”, then “Execute Command”. Repeat
sending this command until you can observe easier.
Left Right
1) If the probe is on the left of wash well, plus 1 or 2 in “Configuration Parameters for
Rotating Counterclockwise to Inner Ring Reagent Position”
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Chapter 2 Installation and Update
2) If the probe is on the Right of wash well, minus 1 or 2 in “Configuration Parameters for
Rotating Counterclockwise to Inner Ring Reagent Position”
Then Click “Effectuate configuration” buttons.
Step 4
Select “Vertical Reset”, then “Execute Command”.
Step 5
Select “Rotary Reset”, then “Execute Command”.
Repeat Step 2- 5 until the probe is in the center of the reagent bottle
(Attention: it will be ok if the probe doesn’t collide, no need to make it 100% center)
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Chapter 2 Installation and Update
If the mixer in any of these positions are not in center, please adjust its parameters, the
detail procedure is listed below.
Step 1
In tab “Sample probe parameters”, select “Reaction Disk Rotary Reset”, then choose
“Execute Command” button, click it to send command.
Step 2
In tab “Mixing bar parameters”, select “Rotate to Reaction Disk” command, then “Execute
Command”.
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Chapter 2 Installation and Update
Step 3
Select “Lower specified steps”, input value “10”, then “Execute Command”.
Normally mixer will be above No. 42 cuvette position, repeat sending this command until
the mixer reach the surface of the cuvette so that you can observe easier.
Left Right
Step 4
1) If the mixer is on the left of No. 1 cuvette center, minus 1 or 2 in “Configuration
Parameters for Mixing bar rotating Clockwise to Reaction Disk Position”
2) If the mixer is on the Right of No. 1 cuvette center, plus 1 or 2 in “Configuration
Parameters for Mixing bar rotating Clockwise to Reaction Disk Position”
Then “Save configuration”, “Effectuate configuration”
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Chapter 2 Installation and Update
Step 5
Select “Vertical Reset”, then “Execute Command”.
Step 6
Select “Rotary Reset”, then “Execute Command”.
Step 1
Select mixer “Rotary Reset”, then “Execute Command”.
Step 2
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Chapter 2 Installation and Update
Select “Lower specified step”, input value “10”, then “Execute Command”. Repeat sending
this command until the mixer reach the surface of the cuvette so that you can observe
easier.
Left Right
Step 3
1) If the mixer is on the left of wash well, minus 1 or 2 in “Configuration Parameters for
Mixing Bar Rotating Clockwise to wash well position”
2) If the mixer is on the Right of wash well, plus 1 or 2 in “Configuration Parameters for
Mixing Bar Rotating Clockwise to wash well position”
Then “Save configuration”, “Effectuate configuration”
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Chapter 2 Installation and Update
Step 4
Select “Vertical Reset”, then “Execute Command”.
Step 5
Select “Rotary Reset”, then “Execute Command”.
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Chapter 2 Installation and Update
3. Select command “Liquid perfusion” from the list on the left side and click “Send” button.
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Chapter 2 Installation and Update
4. Wait for a while until water from probe wash well, probe interior and mixer wash well can
be seen. For analyzer with auto wash unit, the auto wash unit will wash cuvettes several
times, make sure water can be seen inside the cuvettes during washing.
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Chapter 2 Installation and Update
5.3 For analyzer with auto wash unit, please find tube No.12, cut the tie and use a small cup to
save the water that coming out from the tube. Once you see water coming out from the tube, in
software send command “Close the pump/valve”, water will stop. Tie this tube and make sure no
more water coming out from it. In software send command “Liquid perfusion”, check and confirm
no liquid leakage from this tube.
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Chapter 2 Installation and Update
5.4 Remove air bubble by knocking the side wall of the syringe module with a rubber hammer.
5.5 Select command “Close the pump/valve” from the list on the left side and click “Send”
button.
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Chapter 2 Installation and Update
Power on the main power supply and the keep the power supply of analyzing unit is off.
Measure the no-loads output voltage (not connect to the lamp) of lamp power supply
module with multimeter and adjust the photentiometer to make the voltage of lamp
terminal in the range of 11.93V-12.03V.
2.9 Test
Restart the analyzer, log on software then it is ready to test.
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Chapter 4 Fluid Path and Temperature Control System
The analyzer consists of main board, driver board, sensor board, liquid level detection
board, serial port board, photoelectric board, temperature control board of reagent
refrigeration, etc.
Main board controls the modules to run properly. Driver board receives the control
signals of main board to drive the stepper motor and sensor signals of integrated position to
locate the subassemblies precisely, also receives the control signals of main board to turn
on/off the pump/valve for the liquid system. Photoelectric board converts the light signal into
digital signal that can be processed by computer. Temperature control board of reagent
refrigeration controls the reagent refrigeration temperature to refrigerate the reagent.
NOTE
1. Turn off the main power before replacing any circuit board.
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Chapter 4 Fluid Path and Temperature Control System
40
Chapter 4 Fluid Path and Temperature Control System
41
Chapter 4 Fluid Path and Temperature Control System
42
Chapter 4 Fluid Path and Temperature Control System
43
Chapter 4 Fluid Path and Temperature Control System
Sensor board collects sensor signals, such as motor initial position signal, coder signal
of motors, and then converts the signals to main board by a signal cable. This prevents the
connection between the sensor cable and main board being in a mess and also prevents the
signal cables from interfering each other. Senor board cooperates with motor driving circuit
to control the driving units of analyzer precisely.
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Chapter 4 Fluid Path and Temperature Control System
U2
J1
5V
Inverter
Signal
...
Main
board
Inverter
GND
U1
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Chapter 4 Fluid Path and Temperature Control System
46
Chapter 4 Fluid Path and Temperature Control System
Liquid level detection board has the functions of liquid level detection and anti-collision
signal detection. The single chip microcomputer and digitally controlled potentiometers (DCP)
on the board can adjust the DCP resistance automatically when powering on to make the
liquid level detection board work at proper position.
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Chapter 4 Fluid Path and Temperature Control System
NOTE
Power off the liquid level detection board after programming and you can work
properly only after powering on again. Press the reset button if you want to
replace the probe when still powering on. And reset again after adjusting.
Phenomena Description
D5 is off. It occurs when there is no collision or liquid level detection.
D4 is off.
The board is abnormal if the light is off when there is collision or
liquid level detection. Do the troubleshooting.
D5 is on constantly. There is collision.
D5 glitter alone. It means that the probe replacing and adjusting is finished.
Power off again or press reset button S2 on the board.
It may be because the detecting probe is in the liquid or the
removing of other parts causes DCP re-adjustment. Press reset
button S2 or power on again to adjust DCP automatically and
check.
D4 glitters for one It occurs when detects the liquid level. (The on-time depends on
time and then will the liquid volume. If the liquid volume is more, the on-time will be
be off. longer.)
D4 glitters alone. Do not power off when adjusting automatically after replacing the
probe. The adjusting time is less than 20 seconds. If D5 glitters
alone for a long time, there may be other problems.
D5 and D4 glitter in It may be because the detecting probe is abnormal. Detecting
turns. probe capacitance is beyond the proper range. Replace the
detecting probe.
The working position cannot be adjusted because of DCP
problems.
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Chapter 4 Fluid Path and Temperature Control System
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Chapter 4 Fluid Path and Temperature Control System
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Chapter 4 Fluid Path and Temperature Control System
Power supply boards supply power to all the boards and parts that need power to work.
Function: AC input and DC output of 5V, 12V and 24V
51
Chapter 4 Fluid Path and Temperature Control System
• Power supply B is 12V, when the main power switch is on, B is working, output power
to the temperature control board (cooling reagent) and the cooling pump & fan.
• After switching on analyzing unit power, A (24V) and C (5V) are working together with
• After logging in software and finishing the initialization, driver board J14 output 12V
to Relay E, so the Relay E works to enable D (12V) start to work, thus the lamp is
turned on.
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Chapter 4 Fluid Path and Temperature Control System
Mixer wash
It consists of one liquid pump and wash pool.
Working procedure: The liquid pump provides water to wash mixer exterior when flowing
through water inlet of wash pool. And then the waste liquid is drained out through water
outlet of wash pool and corresponding tubes to waste bucket.
Water cooling
It consists of a water coolant pump, cooling fan.
Working procedure: The water coolant pump provides antifreeze water, water flows
through the socket of water-cooling light source and the heat side of peltier under the
reagent disk pot and then go into a radiator which the fan can cool down the temperature of
the water, the cooled water return back into the coolant pump and repeat the cycle.
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Chapter 4 Fluid Path and Temperature Control System
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Chapter 4 Fluid Path and Temperature Control System
55
Chapter 5 Removing Subassemblies
56
Chapter 5 Removing Subassemblies
The heating and cooling system can be divided into reaction disk temperature control
module, reagent disk refrigeration module, analyzer heat-diffusion module, etc.
1 Reaction disk temperature control effect: The temperature of the liquid in the reaction
cuvette rises to and keeps at 37℃ in the temperature control chamber.
2 When there is sensor failure or hardware board failure, the configuration temperature
protection switch of reaction disk temperature control module prevents from the
overheating of the device.
3 The reagent disk uses the semiconductor (Peltier) refrigeration technology and
water-cooling and heat-diffusion method. The reagent disk temperature lowers down
quickly after startup, the temperature of the bottom close to peltier keeps at 4~12℃.
4 The refrigeration module diffuses heat by heat-diffusion tube, water-cooling pump and
fan.
5 Circulating water is also used for heat-diffusion of lamp to prevent the heat of light
source module from effecting other modules.
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1. Functions
2. Specifications
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You need to adjust the lamp AD value after a new lamp is installed, or if the AD value of any
wavelength is not within the correct range, “Photoelectric Adjustment Assistant” tool is
provided to adjust the AD value.
Please make sure that the lamp has been turned on for at least 30 minutes to ensure
stable light intensity before doing this adjustment procedure.
4.1 Exit the Chemistry analyzer software, keep both the main power switch and analyzing
unit power switch of the Chemistry analyzer on, and run “Photoelectric Adjustment
Assistant”. You can find in in desktop, or go to folder
“D:\AutoClient\Tools\PhotoelectricAdjustmentAssistant” and double click it to run.
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4.3 Take out the cuvette from the reaction disk, let the light from the lamp go directly to the
photoelectric board.
4.4 In “Channel list”, select the channels that have abnormal AD values. For new lamp,
please select all channels.
Channel 1 2 3 4 5 6 7 8
Wavelength 340nm 405nm 450nm 510nm 546nm 578nm 630nm 670nm
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compartment.
Wash pool: providing the reagent probe, sample probe and mixer with interior/exterior
wash site.
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4 Back door
Unscrew screws to move away the back door.
5 Panel
The panel consists of left panel, right panel, sample disk cover, reagent disk cover,
and reaction disk cover.
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Note:
Protect the sample probes and reagent probes and rotate the probe rocker to
a safe location when installing and removing the panel.
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Composition
Reaction disk and temperature control unit consists of reaction disk subassembly,
reaction disk driving subassembly, coder sensor subassembly, and temperature control
subassembly.
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The temperature control subassembly is used for keeping the reaction cuvette constant
temperature.
Structure
Reaction disk temperature control subassembly structure figure:
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Chapter 5 Removing Subassemblies
Reaction disk subassembly consists of 50 plastic reaction cuvettes, plastic disk, and
sensor baffle plate. Press the reaction cuvettes into the reaction disk.
Note:
The light-penetration surface cannot be touched by hands or other dirty
things and it is vertical to the disk radial direction when installing.
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The reaction driving subassembly is tightened to the backplane by six screws M3x12.
And the motor bracket is tightened to the backplane by four screws M3x8. Locate the
raised part under the pedestal to the corresponding installation hole of the large backplane,
and then tighten the screws.
Reaction disk driving subassembly rotation structure figure:
The bearing and bushing are connected by shaft and tightened with socket head screws
M3x16. The pedestal is tightened by six socket head screws M3x12 on the backplane.
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The distance between the bottom of the pinion and the top of the motor is 3mm.
Align the M3x4 lock screw to the rotating shaft facet and tighten the screw.
There are long slot holes on bracket 1 and 2 and located by two pins. When the
reaction disk gear and sensor baffle plate are intervened by photoelectric sensor,
or adjusting the corresponding positions of the reaction disk and wash system,
loosen the screws to move the brackets. Tighten the screws until they are not
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intervened.
The reagent/sample disk subassembly holds the reagent/sample cuvettes and drives the
reagent/sample disk to rotate to the specified position. It helps the reagent probes aspirate
reagent/sample and dispense sample to reaction cuvettes. And the reaction disk has the
function of refrigeration to ensure the stability of the reagents and reducing volatilization, it
also can input the reagent information automatically. Three loops, 40 reagent/sample
positions. It rotates clockwise/counterclockwise.
Composition and structure
Reagent/sample disk unit position figure:
Composition
Reagent/sample disk subassembly:
The reagent/sample disk subassembly holds the reagent cuvettes and is driven by the
driving subassembly to rotate. It provides sample probe with reagent/sample and consists
of handle, reagent cuvette base, reagent disk bracket, center canister, and center canister
cover.
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The reagent/sample disk subassembly consists of handle, reagent cuvette base, reagent
cuvette, reagent disk bracket, center canister cover, center canister, and screws.
Reagent/sample disk subassembly figure:
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Install the rotating shaft subassembly to the large backplane position hole, tighten it with
six socket head screws M3x12. Install the motor subassembly to the position hole, strain
the synchronous belt, tighten it with four socket head screws M3x8.
Tighten the sensor subassembly with the socket head screws M3x6 according to the
positions of sensor baffle plate and coder adjustment sensor subassembly.
Install the connector after installing the reagent refrigeration pot with three socket head
screws M4x20. Align the connector to the position pin when installing
.
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Sample probe subassembly includes sample probe. Sample probe is used for
dispensing sample and reagent to reaction cuvettes. Driving subassembly drives the
circulation motion of the sample probe on the reagent/sample disk (electrolyte),
reaction disk, and wash pool.
The sample probe has the functions of detecting liquid level, preventing from being
collided in vertical motion and rotary motion.
Sample probe subassembly figure:
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Chapter 5 Removing Subassemblies
The sample probe driving subassembly can drive the rocker subassembly to do the
speedy vertical motion and rotary motion respectively.
The sample probe driving subassembly consists of pedestal subassembly, linear motion
subassembly, and rotary motion.
The pedestal subassembly consists of chassis and bracket and is used for supporting
and fixing the motors and moving system.
The linear motion subassembly consists of stepper motor, belt pulley, belt pulley axle,
synchronous belt, guide shaft, driving block, axletree, briquetting, sensor baffle plate, and
photoelectric sensor.
The rotary motion subassembly consists of stepper motor, belt pulley, belt pulley axle,
synchronous belt, axle, axletree, rotating rocker, position coder, and photoelectric sensor.
The position coder of every driving subassembly is different because the trajectory of
every probe is different and the components are the same except the coder.
The sample probe driving subassembly figure:
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Install the driving subassembly to the large backplane with six socket head screws
M3x16 and unplug the motor connection and sensor connection before removing it.
Sample probe rocker subassembly consists of upper cover, lower cover, sample probe
subassembly, sliding cover, liquid level detection board, supporting pedestal of liquid level
detection board, platen, and fixed axis.
1 The rocker subassembly is connected by fixed axis and driving subassembly and
tightened by a socket head screw M3x8. Loosen the screw to remove rocker
subassembly or adjust the rocker position. Notice that protect the connection when
removing and protect the probe when adjusting.
2 Extrude two sides of lower cover to separate from the pothook and then open the
upper cover. Fix the fixed axis and lower cover with two socket head screws M3X8 and
gasket. There is a long slot on the lower cover. Loosen the screws to move about
1.5mm to adjust the position of the lower cover.
3 Sample probe (reagent probe) is limited by the sliding cover in the copper hole. Loose
two cross head screws M2.5x4 and undraw the sliding cover to take out the sample
probe (reagent probe). Check the vertical motion of the probe and anti-collision
function when installing.
Sample probe rocker subassembly figure:
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The mixer driving subassembly drives the mixer roc k, axletree, briquetting, sensor
baffle plate, photoelectric sensor, and linear motion stop block.
The rotary motion subassembly consists of stepper motor, belt pulley, belt pulley axle,
synchronous belt, axle, axletree, rotating rocker, position coder, and photoelectric
sensor.
Mixer driving subassembly figure:
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Install the driving subassembly to the large backplane with six socket head screws M3x16
and unplug the motor connection and sensor connection before removing it. Mind the
whole direction of the driving subassembly.
Mixer rocker subassembly consists of upper cover, lower cover, motor, mixer, and fixed
axis.
1 The rocker subassembly is connected by fixed axis and driving subassembly and
tightened by a socket head screw M3x8. Loosen the screw to remove rocker
subassembly or adjust the rocker position. Notice to protect the connection when
removing and protect the probe when adjusting.
2 Extrude two sides of lower cover to separate from the pothook and then open the
upper cover. Fix the fixed axis and lower cover with two socket head screws M3X8 and
gasket. There is a long slot on the lower cover. Loosen the screws to move about
1.5mm to adjust the position of the lower cover.
3 The mixer motor is tightened by three socket head screws M3x6 and gasket. There is
a long slot on the motor connection board to adjust the motor position according to the
requirements.
4 The mixer and motor axis are connected and tightened by two socket head screws
M3x4. The two sides should be symmetrical and tightened gradually. The mixer should
be clenched upwards to the panel of the motor axis in order to prevent the mixer too
long.
Mixer rocker subassembly figure:
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The wash probe subassembly consists of the pedestal and six auto-wash probe
subassemblies from left to right.
Loose the 4 lock screws which used to fix the motor with the bracket if there is position
excursion when washing reaction cuvettes, adjust the wash probes to a good position and
then tight these 4 screws back.
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Chapter 6 System Maintenance
Probe-collision Failure
Make sure the position of probe –collision, the probe –collision may occur in reaction
disk, wash pool, reagent disk/sample disk, and acid/alkali wash solution position.
1 If the failure occurs in wash pool or acid/alkali wash solution position and the panel is
proper, it may be the problem of vertical position parameters of sample probe itself
and solve the problem by editing the parameters.
2 If the failure occurs in reaction disk, reagent disk, or sample disk, make sure if it is pot
locating failure or probe locating failure. If the trajectory is at the cuvette port, it is the
probe problem. And if the probe-collision occurs in the trajectory of the cuvette port, it
is disk location problem, check the disk driving motor. Check the tightness degree of
strap of reagent/sample disk. Check the gear of the reaction disk (Gear failure is
seldom).
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If the position of wash pool is still improper after adjusting the position of mixer, adjust the
position of wash pool. Open the left panel, and adjust the position of wash pool bracket.
There are long holes on the bracket in two directions, and then loosen the screws to
adjust the position of wash pool.
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1 2 3
Sample tube Cuvette Wash pool
1 2 3
Reagent bottle Cuvette Wash pool
Do the fine tuning for the sample probe rocker if there is sample probe excursion
relative to reaction disk, sample tube, and reagent bottle. Loosen two socket head screws
M3x8 of the fixed axis and rotate the rocker to adjust the position. Open the upper cover of
the rocker and loosen three socket head screws M3x8 to adjust the extended length of the
rocker.
See the figures below:
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The Leakage
1 The leakage may occur at the left side frequently and the reason is that the water
supply system is on the left. Open the left side door to check the leakage and reasons
are as follows:
a) The joint between the exhauster connectors/pump outlets and the tubes falls off
or loosens. Resect a short tube, connect again and tighten with the belt and nip
with soft clip.
b) The sample probe interior wash pump passes by the filter (The problem may be
caused by the high pressure, pull and insert several times.) Resect a short tube,
connect again and tighten with the belt.
2 The leakage occurs in the analyzer, check the following points:
a) Check whether the reaction cuvettes overflow or not.
b) Check whether it is the reason that the waste liquid is full or other reason if the
liquid overflows from the wash pool.
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Reaction Cuvette Overflows and Other Failures (only for analyzers with auto wash
system):
Reaction cuvette overflows:
1 Check whether the draining pump (concentrated waste pump) is working or not if only
the 1 wash probe of auto-wash system overflows. If it continue overflow, needs to
replace the tube of peristaltic pump.
2 Check whether all the draining pumps are working proper or not.
3 Check the waste tank, make sure it is not full and the waste outlet tube is above the
waste liquid level.
4 Restart the analyzer and the reaction cuvette does not overflow in several hours.
Judge whether it is caused by software control or not.
Liquid level in reaction cuvettes exit serious inequalities (only for analyzers with auto
wash system):
It may because there is impurity in certain wash probe. Unclog the wash probe with
a soldering tin line. If the problem remains, adjust the one-way valve to check.
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Chapter 6 System Maintenance
1 Check water the probe tubing is too dirty. Wash it with cloth dipped by the enthal
2 Check for leakage on the connection.
3 If the water hangs on the first phase, check for the abrasion of the peristaltic pump
tubing.
Fluctuation Alarm
The fluctuation alarm of the reaction disk may occur about 15 minutes after startup.
Check the sensor connection and heater power supply socket. Check the actual
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temperature in maintenance, record for a time, collect the data, and send the data to
the engineer.
Please send this file to manufacturer. At the same time, please check:
1. Make sure the light source lamp lights power supply is 12V.
2. Make sure the lamp has been turned on automatically after log in start up.
Operation Methods
1 If user wants to keep the history data, please run the new program and install this
new version program into the same folder.
2 If user doesn’t want to keep the history data, please remove the old version of pc
program, and then manually delete the installation folder. And then do a new
installation of new version software.
1. Keep both the main power switch and analyzing unit power switch of the Chemistry
analyzer on, and run “ISPUnitProcess.exe”. You can find in the software installation folder:
D:\AutoClient\Tools\ISPUnitProcess
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2. Click the pull-down arrowhead on the upper-right corner of screen to configure the
“Communication setup”, Port: COM1, and the others are the default settings. (The
other settings cannot be changed, Baud rate:19200, Data bit:8, Parity bit: None, Stop
bit: One).
3. Click the sign behind each unit in “Unit list” to display the dialog box: select
corresponding hex file according to corresponding unit, and then click “Open”.
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If the programming is finished, the letters are green. If the programming is going on,
the letters are blue. If the letters are black, it means that the programming is not
started. And if the letters are red, it means that the programming fails.
It will take about 8 minutes to program all the files, please wait patiently.
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If there is failure prompt in programming results (The letters are red.), program the
corresponding unit again. Power on main board again if “Cancel programming” appears in
programming procedure, click “Program”, and programming still fails. And then repeat
above operations. If the programming is finished, the letters are green.
The SCM (single chip micyoco) programming of main board is suitable for on-line
programming mode, you can program the file with computer chassis closed.
Note:
1. The software will back up the database daily during startup.
2. The software has manual backup function, manual backup can be
done as required, but the name of the manual backup is the same with
the auto backup, if you do not change the path, the autobackup data
might be overridden.
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3. Select the Backup path and use Manual Backup, click the Backup Button to start the
backup.
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5. Click Ok, and close the window to return to the login screen, manual backup is
completed.
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2. Select the data to be restored, if you would like to restore the autobackup data,
select the autobackup set path, if you would like to restore the manual backup data,
please select manual backup path. Then Click “Restore” button.
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Chapter 7 Troubleshooting
Chapter 7 Troubleshooting
7.1 Overview
occurs, it identifies the alarm level and handles it with one of the 7 solutions and then
reminds you of the alarm with bright red bar displayed at the bottom of the screen. By
clicking the read bar, you can see the error message, probable causes and corrective
actions.
1. Testing forbidden
2. Testing stopped
All current tests are terminated; the system enters standby mode, waiting for
operation.
All unstarted tests are terminated, while the tests with sample and reagent
6. Warning
7. Prompt
This chapter presents all alarm messages that may occur when the system is running
and recommended corrective actions. When an alarm occurs, find it through the following
table and handle it with its corresponding corrective actions. If the alarm remains, please
contact manufacturer.
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The error message table of the analyzer please refer to the User Manual.
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P0 1 . 9 1 . 3 0 0 3 1 0 - 0 2